iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035482

Ensembl Protein ID

ENSFCAP00000021057.1

UniProt Accession

M3X357; M3X357_FELCA

Genbank Protein ID

ENSFCAP00000021057

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02067540

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000030479.1	ENSFCAT00000024811.1	ENSFCAP00000021057.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.80e-25	87.2	404	475
E3 adaptor/Cullin RING/DCX/DWD	5.60e-41	136.8	11	43
UBD/Beta-Prp	5.00e-55	186.8	7	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFLCPITRELMKDPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLPSVVLTPNRTLKMAISRWLETHQ 475
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l++++
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLSDFT 43
           9*********548***************98876 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  ++sllat s d+ti+++++++ +    + l+ h+ +v +++fsp+g il+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SSSLLATCSLDKTIRLYSLSDFTElpHSPLKLHTYAVHCCCFSPSGHILASCSTDGTTVLWNTQNGEPLAVM 92
           566666655.55899..9********************666667889****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  lvsG +d t+ +w+ ++++ ++ + s++dg+    +++pdgnl+v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCQFSPDSTCLVSGAADGTVVLWNAQSYKLYR-CGSVKDGSLVACAFSPDGNLFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           *765267*********************************9.**********************************8.6678888877. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+           ++l+s+++d ++k+w ++
   Q: 179  HDLGITCCDFSSQPvsdgeqglqyFRLASCGQDCQIKIWVVS 220
           *********9998899999********************776 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLS DFTELPHSPL KLHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTQNGEPLA VMEQPSGSPV RVCQFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAAACATG GTGAAACTAA TCCACACATT AGCTGATCAT GGTGATGATG TCAACTGCTG 60
TGCATTCTCC TCTTCCCTCT TGGCCACTTG CTCTTTGGAC AAAACAATTC GCCTGTACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

fca:101093126

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000612	Aegilops tauschii	53.73	3.00e-17	84.00
IUUC-Aml-001614	Ailuropoda melanoleuca	96.64	0.00e+00	959.00
IUUC-Apl-003529	Anas platyrhynchos	76.47	0.00e+00	771.00
IUUC-Aca-004257	Anolis carolinensis	71.05	0.00e+00	704.00
IUUC-Ame-011357	Astyanax mexicanus	53.01	2.00e-118	418.00
IUUC-Bta-013032	Bos taurus	89.73	0.00e+00	888.00
IUUC-Cja-018743	Callithrix jacchus	92.65	0.00e+00	921.00
IUUC-Cfa-021197	Canis familiaris	94.96	0.00e+00	948.00
IUUC-Cpo-022279	Cavia porcellus	89.29	0.00e+00	896.00
IUUC-Csa-023954	Chlorocebus sabaeus	93.28	0.00e+00	926.00
IUUC-Cho-025083	Choloepus hoffmanni	74.60	8.00e-160	556.00
IUUC-Cin-025786	Ciona intestinalis	34.88	2.00e-79	289.00
IUUC-Dre-028087	Danio rerio	57.00	1.00e-143	503.00
IUUC-Dno-028919	Dasypus novemcinctus	92.44	0.00e+00	921.00
IUUC-Dor-031112	Dipodomys ordii	87.82	0.00e+00	877.00
IUUC-Ete-032405	Echinops telfairi	89.21	0.00e+00	642.00
IUUC-Eca-033254	Equus caballus	92.02	0.00e+00	912.00
IUUC-Eeu-034545	Erinaceus europaeus	85.71	0.00e+00	833.00
IUUC-Fal-036976	Ficedula albicollis	62.35	3.00e-166	578.00
IUUC-Gmo-039213	Gadus morhua	54.83	1.00e-137	482.00
IUUC-Gga-040561	Gallus gallus	75.26	0.00e+00	756.00
IUUC-Gac-041471	Gasterosteus aculeatus	58.19	8.00e-142	496.00
IUUC-Ggo-045503	Gorilla gorilla	93.28	0.00e+00	929.00
IUUC-Hsa-045910	Homo sapiens	93.28	0.00e+00	929.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	89.92	0.00e+00	711.00
IUUC-Loc-052307	Lepisosteus oculatus	59.52	1.00e-167	582.00
IUUC-Laf-053587	Loxodonta africana	91.60	0.00e+00	914.00
IUUC-Mcc-055679	Macaca mulatta	93.49	0.00e+00	930.00
IUUC-Meu-055962	Macropus eugenii	71.85	0.00e+00	660.00
IUUC-Mga-059652	Meleagris gallopavo	75.05	0.00e+00	759.00
IUUC-Mmr-060943	Microcebus murinus	89.96	0.00e+00	894.00
IUUC-Mdo-062592	Monodelphis domestica	83.51	0.00e+00	832.00
IUUC-Mmu-063577	Mus musculus	81.72	0.00e+00	818.00
IUUC-Mpu-066422	Mustela putorius furo	94.75	0.00e+00	939.00
IUUC-Mlu-067250	Myotis lucifugus	92.23	0.00e+00	910.00
IUUC-Nle-069517	Nomascus leucogenys	93.07	0.00e+00	928.00
IUUC-Opr-070776	Ochotona princeps	89.29	0.00e+00	881.00
IUUC-Ont-071821	Oreochromis niloticus	57.74	3.00e-151	528.00
IUUC-Oan-073706	Ornithorhynchus anatinus	83.58	0.00e+00	837.00
IUUC-Ocu-074766	Oryctolagus cuniculus	81.67	0.00e+00	795.00
IUUC-Ola-086531	Oryzias latipes	56.63	5.00e-146	510.00
IUUC-Oga-088388	Otolemur garnettii	89.71	0.00e+00	897.00
IUUC-Oar-089748	Ovis aries	89.94	0.00e+00	886.00
IUUC-Ptr-090616	Pan troglodytes	93.02	0.00e+00	921.00
IUUC-Pan-091769	Papio anubis	92.73	0.00e+00	666.00
IUUC-Psi-093334	Pelodiscus sinensis	79.41	0.00e+00	744.00
IUUC-Pma-094383	Petromyzon marinus	48.44	3.00e-132	464.00
IUUC-Pfo-096801	Poecilia formosa	56.58	7.00e-148	516.00
IUUC-Pab-098139	Pongo abelii	92.27	0.00e+00	749.00
IUUC-Pca-100523	Procavia capensis	76.26	0.00e+00	734.00
IUUC-Pva-102286	Pteropus vampyrus	91.18	0.00e+00	875.00
IUUC-Rno-104831	Rattus norvegicus	83.82	0.00e+00	837.00
IUUC-Sha-107499	Sarcophilus harrisii	84.66	0.00e+00	845.00
IUUC-Sar-113389	Sorex araneus	86.55	0.00e+00	840.00
IUUC-Tgu-116769	Taeniopygia guttata	74.37	0.00e+00	740.00
IUUC-Tru-118774	Takifugu rubripes	54.12	1.00e-139	489.00
IUUC-Tsy-119595	Tarsius syrichta	80.58	0.00e+00	648.00
IUUC-Tni-119850	Tetraodon nigroviridis	57.42	1.00e-147	516.00
IUUC-Tur-126683	Triticum urartu	53.03	4.00e-17	83.60
IUUC-Tbe-127938	Tupaia belangeri	81.97	6.00e-147	513.00
IUUC-Ttr-128193	Tursiops truncatus	91.75	0.00e+00	775.00
IUUC-Vpa-130275	Vicugna pacos	94.54	0.00e+00	933.00
IUUC-Xtr-131982	Xenopus tropicalis	61.68	3.00e-170	591.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence