iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074766

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02004444

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015135.3	ENSOCUT00000022951.2	ENSOCUP00000023654.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-24	85.5	405	476
E3 adaptor/Cullin RING/DCX/DWD	4.60e-36	121.3	11	42
UBD/Beta-Prp	5.10e-56	190.1	4	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+ef+CpI+ elM++Pv++++G++y+++++e w++++++t+P+t+  l++  l+Pn tl+  i++w+e+++
   Q: 405  IPDEFICPITRELMKEPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLSSVVLTPNRTLKMAINRWLETHQ 476
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtg 33
           H d+v+c+afs+ ll+++s D++i++++l ++
   Q: 11   HGDDVSCCAFSSSLLATCSLDKSIRLYSLGDF 42
           99********548**************98666 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcle 130
           ll++l  h + v+++ fs++  +l+t+s D+ i++++l   t  + + lk h++ v ++ fspsg++l+s s d t  +w++++gq l 
   Q: 4    LLHTLAHHGDDVSCCAFSSS--LLATCSLDKSIRLYSLGdfTELPHSPLKFHSYAVHCCCFSPSGHVLASCSTDGTTVLWNTQNGQTLA 90
           7899****************..9*************999444445566899*************************************9 PP
   S: 131  etlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++++  + v++ +++pd+ +l+sG++D+tv lW+ ++ kl r  +  +++s    +f++ng +lv+gs  g++++wd +   c+++ +
   Q: 91   VMEQPSGSPVRVCRFSPDSTCLASGAADGTVVLWNAQSHKLHRCGSV-KDGSLVACAFSPNGSFLVTGSSCGDLTVWDDKMR-CLHSEK 177
           999999999*************************9988888777665.999999************************9655.****** PP
   S: 220  ghtdnvksvrfspnderl 237
           +h+  +++ +fs      
   Q: 178  AHDLGITCCDFS---SQP 192
           *********999...444 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MVTLLHTLAH HGDDVSCCAF SSSLLATCSL DKSIRLYSLG DFTELPHSPL KFHSYAVHCC 60
CFSPSGHVLA SCSTDGTTVL WNTQNGQTLA VMEQPSGSPV RVCRFSPDST CLASGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATTAACTA GACCTTGGAA CTTGTGCTTC CTCAGCTGAG AGAAAACTGC AGCGAAGATA 60
CTCACGTCGG AACTCCTGAT TCTCCGAGGG CCTTAATTCC TAGACCTTCC GACCCCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000753	Aegilops tauschii	52.11	6.00e-18	85.90
IUUC-Aml-001614	Ailuropoda melanoleuca	81.88	0.00e+00	797.00
IUUC-Apl-003529	Anas platyrhynchos	68.18	0.00e+00	660.00
IUUC-Aca-004257	Anolis carolinensis	64.56	3.00e-180	624.00
IUUC-Ame-011357	Astyanax mexicanus	47.19	2.00e-102	365.00
IUUC-Bta-013032	Bos taurus	79.63	0.00e+00	778.00
IUUC-Cja-018743	Callithrix jacchus	83.33	0.00e+00	803.00
IUUC-Cfa-021197	Canis familiaris	81.88	0.00e+00	801.00
IUUC-Cpo-022279	Cavia porcellus	80.42	0.00e+00	784.00
IUUC-Csa-023954	Chlorocebus sabaeus	83.75	0.00e+00	805.00
IUUC-Cho-025083	Choloepus hoffmanni	64.04	4.00e-128	450.00
IUUC-Cin-025786	Ciona intestinalis	31.70	5.00e-67	248.00
IUUC-Dre-028087	Danio rerio	52.04	2.00e-129	456.00
IUUC-Dno-028919	Dasypus novemcinctus	82.92	0.00e+00	804.00
IUUC-Dor-031112	Dipodomys ordii	80.21	0.00e+00	777.00
IUUC-Ete-032405	Echinops telfairi	76.95	2.00e-152	531.00
IUUC-Eca-033254	Equus caballus	80.00	0.00e+00	776.00
IUUC-Eeu-034545	Erinaceus europaeus	78.54	0.00e+00	738.00
IUUC-Fca-035482	Felis catus	81.67	0.00e+00	795.00
IUUC-Fal-036976	Ficedula albicollis	54.41	3.00e-132	464.00
IUUC-Gmo-039213	Gadus morhua	51.36	9.00e-123	433.00
IUUC-Gga-040561	Gallus gallus	65.90	0.00e+00	645.00
IUUC-Gac-041471	Gasterosteus aculeatus	53.14	1.00e-128	452.00
IUUC-Ggo-045503	Gorilla gorilla	84.38	0.00e+00	815.00
IUUC-Hsa-045910	Homo sapiens	84.58	0.00e+00	817.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	79.42	6.00e-173	599.00
IUUC-Loc-052307	Lepisosteus oculatus	53.54	1.00e-146	513.00
IUUC-Laf-053587	Loxodonta africana	82.71	0.00e+00	802.00
IUUC-Mcc-055679	Macaca mulatta	83.96	0.00e+00	812.00
IUUC-Meu-055962	Macropus eugenii	64.58	2.00e-163	568.00
IUUC-Mga-059652	Meleagris gallopavo	66.11	0.00e+00	648.00
IUUC-Mmr-060943	Microcebus murinus	80.29	0.00e+00	778.00
IUUC-Mdo-062592	Monodelphis domestica	73.91	0.00e+00	723.00
IUUC-Mmu-063577	Mus musculus	74.53	0.00e+00	724.00
IUUC-Mpu-066422	Mustela putorius furo	81.21	0.00e+00	793.00
IUUC-Mlu-067250	Myotis lucifugus	81.25	0.00e+00	787.00
IUUC-Nle-069517	Nomascus leucogenys	84.17	0.00e+00	812.00
IUUC-Opr-070776	Ochotona princeps	83.30	0.00e+00	806.00
IUUC-Ont-071821	Oreochromis niloticus	53.73	7.00e-135	473.00
IUUC-Oan-073706	Ornithorhynchus anatinus	74.32	0.00e+00	721.00
IUUC-Obr-076354	Oryza brachyantha	50.00	9.00e-18	84.70
IUUC-Ola-086531	Oryzias latipes	52.82	3.00e-129	454.00
IUUC-Oga-088388	Otolemur garnettii	80.42	0.00e+00	779.00
IUUC-Oar-089748	Ovis aries	80.00	0.00e+00	779.00
IUUC-Ptr-090616	Pan troglodytes	84.28	0.00e+00	809.00
IUUC-Pan-091769	Papio anubis	81.90	1.00e-160	558.00
IUUC-Psi-093334	Pelodiscus sinensis	69.94	0.00e+00	646.00
IUUC-Pma-094383	Petromyzon marinus	46.20	7.00e-122	430.00
IUUC-Pfo-096801	Poecilia formosa	51.76	4.00e-128	451.00
IUUC-Pab-098139	Pongo abelii	83.67	0.00e+00	653.00
IUUC-Pca-100523	Procavia capensis	84.23	1.00e-158	552.00
IUUC-Pva-102286	Pteropus vampyrus	80.42	0.00e+00	756.00
IUUC-Rno-104831	Rattus norvegicus	77.45	0.00e+00	752.00
IUUC-Sha-107499	Sarcophilus harrisii	76.04	0.00e+00	741.00
IUUC-Sar-113389	Sorex araneus	77.29	0.00e+00	730.00
IUUC-Tgu-116769	Taeniopygia guttata	64.58	7.00e-178	616.00
IUUC-Tru-118774	Takifugu rubripes	49.59	2.00e-123	435.00
IUUC-Tsy-119595	Tarsius syrichta	75.00	6.00e-173	599.00
IUUC-Tni-119850	Tetraodon nigroviridis	50.95	1.00e-126	446.00
IUUC-Tbe-127938	Tupaia belangeri	68.93	1.00e-115	409.00
IUUC-Ttr-128193	Tursiops truncatus	79.21	0.00e+00	649.00
IUUC-Vpa-130275	Vicugna pacos	81.46	0.00e+00	789.00
IUUC-Xtr-131982	Xenopus tropicalis	55.97	5.00e-149	520.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence