iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	21389113

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Non-SCF-type F-box protein involved in the endocytic with the vacuolar sorting pathway. Acts as a repressor of YPT52 by inhibiting the formation of active, GTP-bound, YPT52. Involved in the defense mechanism against methylmercury toxicity.

Protein Sequence
(Fasta)

MAFQDQDIFI VFSHASLFLN QNDLLSLSLT SKKMHDMIAI PRLYSNIHIT KNPVLRTNKW 60
FLDGGKTYVS GYRSVLKTGD KNDIFLYDRI ERLLETSHLK CIKQLTIDED LFHNREEGLQ 120

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Nucleotide Sequence
(Fasta)

ATGGCATTCC AAGATCAAGA TATATTCATA GTGTTCTCGC ATGCCTCCTT ATTTCTTAAT 60
CAAAATGATT TATTAAGCCT AAGTCTAACA TCCAAAAAAA TGCATGACAT GATTGCAATC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0472--Membrane
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR032675--L_dom-like

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0005634--C:nucleus
GO:0005095--F:GTPase inhibitor activity
GO:0006897--P:endocytosis
GO:0034260--P:negative regulation of GTPase activity
GO:0006623--P:protein targeting to vacuole

KEGG

sce:YMR258C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001756	Ailuropoda melanoleuca	31.03	8.70e-02	28.90
IUUC-Ago-007928	Ashbya gossypii	42.67	3.00e-124	436.00
IUUC-Ang-009506	Aspergillus niger	23.61	1.60e-02	32.00
IUUC-Bci-013870	Botrytis cinerea	33.33	8.00e-03	33.50
IUUC-Cel-018173	Caenorhabditis elegans	29.79	1.00e-02	30.80
IUUC-Cre-022814	Chlamydomonas reinhardtii	24.07	8.80e-01	27.70
IUUC-Cgl-026622	Colletotrichum gloeosporioides	43.75	9.00e-03	32.30
IUUC-Dre-027695	Danio rerio	30.10	6.00e-03	36.60
IUUC-Eca-034099	Equus caballus	29.03	6.00e-03	30.80
IUUC-Gga-040250	Gallus gallus	40.91	9.00e-03	31.20
IUUC-Gma-042886	Glycine max	32.20	2.80e-02	30.80
IUUC-Itr-048772	Ictidomys tridecemlineatus	24.44	1.00e-01	30.80
IUUC-Kpa-049303	Komagataella pastoris	42.26	2.00e-57	214.00
IUUC-Mor-057162	Magnaporthe oryzae	30.51	3.70e-02	31.20
IUUC-Oba-075207	Oryza barthii	31.82	6.00e-03	34.70
IUUC-Ogl-077488	Oryza glaberrima	30.88	5.00e-03	33.50
IUUC-Ogu-078768	Oryza glumaepatula	31.82	5.00e-03	33.50
IUUC-Oni-082058	Oryza nivara	31.82	4.00e-03	33.90
IUUC-Oru-084574	Oryza rufipogon	31.82	5.00e-03	33.50
IUUC-Osa-086099	Oryza sativa	31.82	5.00e-03	33.50
IUUC-Oga-088716	Otolemur garnettii	55.00	1.10e-02	30.80
IUUC-Pop-100074	Populus trichocarpa	38.89	4.00e-03	33.10
IUUC-Pgr-103265	Puccinia graminis	29.85	2.30e-02	30.00
IUUC-Pyt-104651	Pyrenophora triticirepentis	38.24	2.50e-02	32.70
IUUC-Sly-111044	Solanum lycopersicum	40.82	2.30e-02	31.20
IUUC-Tni-120484	Tetraodon nigroviridis	32.81	9.00e-03	31.20
IUUC-Vda-129808	Verticillium dahliae	46.43	5.50e-01	28.10
IUUC-Xtr-132338	Xenopus tropicalis	33.33	2.00e-03	32.30
IUUC-Xma-133196	Xiphophorus maculatus	44.12	5.70e-02	30.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence