iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033759

UUCD1 version

UUC-EqC-00476

Ensembl Protein ID

ENSECAP00000002145.1

UniProt Accession

F6XQV6; F6XQV6_HORSE

Protein Name

Uncharacterized protein

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000003151.1	ENSECAT00000002995.1	ENSECAP00000002145.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.70e-10	39.5	14	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadClqkw.....pglknssskefrCPlCr 46
           C++C+e f        ++l+CgH+f++dCl k+     ++ +   ++++ CP+Cr
   Q: 14   CPVCYEKFrdleG-ASRTLSCGHMFCHDCLVKYllstrVDGQ--VQRTIVCPICR 65
           ********55532.3899************999888665555..889999****8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSEGESKDSL GSECPVCYEK FRDLEGASRT LSCGHMFCHD CLVKYLLSTR VDGQVQRTIV 60
CPICRYVTFL SKKSSRWPSM LDKSSQSLAV PMGLPTVPPL DTMGHTNPLA ISQPVWRPSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGAAG GGGAGAGCAA GGACAGCTTG GGCAGCGAGT GCCCCGTGTG CTACGAGAAG 60
TTCCGAGATC TGGAGGGCGC CAGCCGGACA CTGAGCTGTG GCCATATGTT CTGCCATGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

ecb:100062634

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	81.48	2.00e-48	184.00
IUUC-Atr-002488	Amborella trichopoda	33.33	2.00e-06	46.20
IUUC-Apl-003509	Anas platyrhynchos	45.83	9.00e-35	139.00
IUUC-Aca-004916	Anolis carolinensis	36.60	3.00e-23	101.00
IUUC-Ath-007395	Arabidopsis thaliana	32.35	6.00e-07	47.80
IUUC-Bta-013443	Bos taurus	85.29	2.00e-71	261.00
IUUC-Cja-019637	Callithrix jacchus	82.93	2.00e-66	244.00
IUUC-Cfa-020737	Canis familiaris	81.76	2.00e-66	244.00
IUUC-Cpo-022224	Cavia porcellus	86.50	2.00e-67	248.00
IUUC-Csa-024175	Chlorocebus sabaeus	82.68	9.00e-77	279.00
IUUC-Dre-028060	Danio rerio	37.14	1.00e-22	99.40
IUUC-Dno-030024	Dasypus novemcinctus	83.44	6.00e-69	253.00
IUUC-Dor-030936	Dipodomys ordii	86.47	2.00e-75	274.00
IUUC-Fal-037142	Ficedula albicollis	43.65	3.00e-28	117.00
IUUC-Gmo-039196	Gadus morhua	40.14	1.00e-21	96.30
IUUC-Gga-041189	Gallus gallus	47.10	4.00e-33	134.00
IUUC-Gac-041497	Gasterosteus aculeatus	37.50	5.00e-22	97.10
IUUC-Ggo-045020	Gorilla gorilla	85.45	2.00e-73	268.00
IUUC-Hsa-046317	Homo sapiens	83.64	5.00e-67	246.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	89.41	3.00e-80	290.00
IUUC-Lch-049885	Latimeria chalumnae	39.52	3.00e-23	101.00
IUUC-Laf-053457	Loxodonta africana	81.56	3.00e-71	260.00
IUUC-Mcc-054653	Macaca mulatta	82.28	1.00e-66	245.00
IUUC-Mga-059753	Meleagris gallopavo	46.37	2.00e-35	141.00
IUUC-Mdo-062993	Monodelphis domestica	73.15	4.00e-70	257.00
IUUC-Mmu-063225	Mus musculus	86.47	1.00e-69	255.00
IUUC-Mpu-066299	Mustela putorius furo	84.71	3.00e-68	250.00
IUUC-Mlu-066988	Myotis lucifugus	85.47	2.00e-69	255.00
IUUC-Nle-069011	Nomascus leucogenys	83.54	1.00e-68	252.00
IUUC-Opr-070258	Ochotona princeps	86.59	1.00e-70	258.00
IUUC-Ont-071886	Oreochromis niloticus	40.24	2.00e-23	101.00
IUUC-Ocu-074282	Oryctolagus cuniculus	91.18	7.00e-74	269.00
IUUC-Oga-088403	Otolemur garnettii	78.21	1.00e-70	258.00
IUUC-Oar-089665	Ovis aries	81.63	5.00e-20	88.60
IUUC-Ptr-090580	Pan troglodytes	84.24	2.00e-68	251.00
IUUC-Pan-092447	Papio anubis	82.91	2.00e-67	248.00
IUUC-Psi-093673	Pelodiscus sinensis	45.21	4.00e-37	147.00
IUUC-Ppa-095340	Physcomitrella patens	36.49	1.00e-07	50.40
IUUC-Pfo-096933	Poecilia formosa	37.18	2.00e-20	92.00
IUUC-Pab-097867	Pongo abelii	83.54	2.00e-64	238.00
IUUC-Pva-102146	Pteropus vampyrus	94.12	9.00e-81	292.00
IUUC-Rno-105897	Rattus norvegicus	88.82	3.00e-71	260.00
IUUC-Sha-107282	Sarcophilus harrisii	69.50	2.00e-55	208.00
IUUC-Sar-113260	Sorex araneus	91.18	3.00e-83	300.00
IUUC-Ssc-115449	Sus scrofa	84.71	5.00e-57	213.00
IUUC-Tgu-117349	Taeniopygia guttata	42.22	1.00e-28	119.00
IUUC-Xtr-132180	Xenopus tropicalis	38.46	8.00e-24	103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence