iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059676

UUCD1 version

UUC-MeG-00363

Ensembl Protein ID

ENSMGAP00000007772.1

UniProt Accession

G1N6N8; G1N6N8_MELGA

Protein Name

Uncharacterized protein

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007610.1	ENSMGAT00000008554.1	ENSMGAP00000007772.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-17	62.6	64	129
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.60e-09	35.2	163	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 64   CDVTLKVGTKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 129
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 163  PSNCLAVRSFAESHNRIDLMDMADQYACEHFT 194
           89*****************************7 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MASESMVPEQ GKQHPVKGKR RPQQQQTRSS SGDGEDDIFV FEANEAWKDF HSSLLHFFEA 60
GELCDVTLKV GTKLISCHKL VLACVIPYFR AMFLSEMAEA KQTLIEIRDF DGDAIEDLVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG AATCCATGGT CCCAGAGCAG GGAAAACAAC ATCCAGTGAA GGGAAAAAGG 60
CGGCCACAGC AGCAGCAAAC TCGATCTTCC AGCGGTGATG GTGAAGATGA TATCTTTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mgp:100542470

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	90.31	0.00e+00	1156.00
IUUC-Atr-002726	Amborella trichopoda	35.80	2.00e-42	167.00
IUUC-Apl-003978	Anas platyrhynchos	96.76	0.00e+00	1229.00
IUUC-Aca-004958	Anolis carolinensis	87.88	0.00e+00	1114.00
IUUC-Ame-011139	Astyanax mexicanus	83.17	0.00e+00	1083.00
IUUC-Bta-013142	Bos taurus	90.13	0.00e+00	1149.00
IUUC-Bdi-014143	Brachypodium distachyon	38.59	2.00e-42	167.00
IUUC-Cel-018551	Caenorhabditis elegans	40.07	2.00e-129	456.00
IUUC-Cja-019650	Callithrix jacchus	89.53	0.00e+00	1174.00
IUUC-Cfa-021046	Canis familiaris	90.61	0.00e+00	1158.00
IUUC-Cpo-022445	Cavia porcellus	88.85	0.00e+00	1105.00
IUUC-Csa-023642	Chlorocebus sabaeus	89.69	0.00e+00	1176.00
IUUC-Cho-025012	Choloepus hoffmanni	75.22	0.00e+00	852.00
IUUC-Dre-027723	Danio rerio	81.05	0.00e+00	1062.00
IUUC-Dno-028964	Dasypus novemcinctus	90.62	0.00e+00	966.00
IUUC-Dor-030899	Dipodomys ordii	78.15	7.00e-130	457.00
IUUC-Ete-032815	Echinops telfairi	87.72	0.00e+00	1135.00
IUUC-Eca-034162	Equus caballus	90.48	0.00e+00	1139.00
IUUC-Eeu-034660	Erinaceus europaeus	89.32	0.00e+00	1142.00
IUUC-Fca-035659	Felis catus	90.63	0.00e+00	1156.00
IUUC-Fal-037619	Ficedula albicollis	94.33	0.00e+00	1225.00
IUUC-Fox-037999	Fusarium oxysporum	31.17	7.00e-08	50.10
IUUC-Gmo-038546	Gadus morhua	84.54	0.00e+00	1050.00
IUUC-Ggr-040041	Gaeumannomyces graminis	32.19	3.00e-08	52.00
IUUC-Gga-040770	Gallus gallus	99.35	0.00e+00	1228.00
IUUC-Gac-042557	Gasterosteus aculeatus	79.94	0.00e+00	1046.00
IUUC-Gma-043533	Glycine max	30.98	5.00e-37	149.00
IUUC-Ggo-044741	Gorilla gorilla	89.69	0.00e+00	1177.00
IUUC-Hsa-046025	Homo sapiens	89.69	0.00e+00	1177.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	93.44	0.00e+00	1065.00
IUUC-Lpe-051276	Leersia perrieri	32.26	5.00e-38	152.00
IUUC-Loc-052834	Lepisosteus oculatus	82.98	0.00e+00	1019.00
IUUC-Laf-054513	Loxodonta africana	89.50	0.00e+00	1155.00
IUUC-Mcc-054707	Macaca mulatta	89.53	0.00e+00	1173.00
IUUC-Meu-056779	Macropus eugenii	90.03	0.00e+00	1166.00
IUUC-Mmr-061359	Microcebus murinus	89.68	0.00e+00	1138.00
IUUC-Mdo-062527	Monodelphis domestica	88.76	0.00e+00	1152.00
IUUC-Mmu-063112	Mus musculus	86.65	0.00e+00	1141.00
IUUC-Mac-064682	Musa acuminata	34.62	2.00e-41	163.00
IUUC-Mpu-065800	Mustela putorius furo	89.82	0.00e+00	1149.00
IUUC-Mlu-067536	Myotis lucifugus	88.29	0.00e+00	1103.00
IUUC-Nle-069397	Nomascus leucogenys	89.69	0.00e+00	1176.00
IUUC-Opr-070599	Ochotona princeps	89.82	0.00e+00	958.00
IUUC-Ont-072580	Oreochromis niloticus	80.88	0.00e+00	1061.00
IUUC-Oan-073180	Ornithorhynchus anatinus	90.63	0.00e+00	1169.00
IUUC-Ocu-074026	Oryctolagus cuniculus	89.66	0.00e+00	1135.00
IUUC-Obr-076181	Oryza brachyantha	30.74	2.00e-34	140.00
IUUC-Ola-086776	Oryzias latipes	80.16	0.00e+00	1016.00
IUUC-Oga-088651	Otolemur garnettii	90.18	0.00e+00	1146.00
IUUC-Oar-089567	Ovis aries	89.00	0.00e+00	1123.00
IUUC-Ptr-091564	Pan troglodytes	89.69	0.00e+00	1177.00
IUUC-Pan-092578	Papio anubis	89.69	0.00e+00	1176.00
IUUC-Psi-093635	Pelodiscus sinensis	90.24	0.00e+00	1122.00
IUUC-Pma-094660	Petromyzon marinus	61.82	0.00e+00	761.00
IUUC-Pfo-097507	Poecilia formosa	80.45	0.00e+00	991.00
IUUC-Pab-098025	Pongo abelii	89.69	0.00e+00	1177.00
IUUC-Pca-101046	Procavia capensis	82.47	1.00e-174	605.00
IUUC-Ppe-101154	Prunus persica	32.81	5.00e-38	152.00
IUUC-Pva-102359	Pteropus vampyrus	93.41	0.00e+00	875.00
IUUC-Rno-105750	Rattus norvegicus	87.62	0.00e+00	1130.00
IUUC-Sha-107513	Sarcophilus harrisii	90.97	0.00e+00	1180.00
IUUC-Sly-111482	Solanum lycopersicum	33.07	5.00e-42	165.00
IUUC-Stu-112032	Solanum tuberosum	33.46	9.00e-43	167.00
IUUC-Sar-113616	Sorex araneus	69.18	4.00e-115	408.00
IUUC-Ssc-116205	Sus scrofa	90.23	0.00e+00	971.00
IUUC-Tgu-117435	Taeniopygia guttata	94.33	0.00e+00	1214.00
IUUC-Tru-118709	Takifugu rubripes	80.55	0.00e+00	1056.00
IUUC-Tsy-119466	Tarsius syrichta	93.80	0.00e+00	1069.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.29	0.00e+00	1051.00
IUUC-Tbe-127704	Tupaia belangeri	91.61	0.00e+00	1023.00
IUUC-Ttr-128892	Tursiops truncatus	92.44	0.00e+00	886.00
IUUC-Vpa-130545	Vicugna pacos	90.22	0.00e+00	969.00
IUUC-Xtr-132289	Xenopus tropicalis	83.77	0.00e+00	1040.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence