iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105978

Ensembl Protein ID

ENSRNOP00000035859.4

UniProt Accession

B1WBS3; ZBT42_RAT

Genbank Protein ID

AAI61864.1

Protein Name

Zinc finger and BTB domain-containing protein 42

Genbank Nucleotide ID

BC161864

Gene Name

Zbtb42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000037562.2	ENSRNOT00000030879.4	ENSRNOP00000035859.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.70e-14	53.6	24	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgklde 67
           +D+++ vg+ +f+ah++vLaa+S +F+ lf+ + + s  +++v ++ d v   +f+ ll+F+Y g+ld+
   Q: 24   CDCTVLVGDARFPAHRAVLAACSVYFH-LFYRDQPASS-RDTVRLNgDiVTVPAFSRLLDFMYEGRLDL 90
           8*************************8.7778888775.9******87*******************97 PP

Organism

Rattus norvegicus

Functional Description
(View)

Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes.

Protein Sequence
(Fasta)

MEFPEHGVRL LGRLRQQREL GFLCDCTVLV GDARFPAHRA VLAACSVYFH LFYRDQPASS 60
RDTVRLNGDI VTVPAFSRLL DFMYEGRLDL HSLPVEDVLA AASYLHMYDI VKVCKGRLRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCCTCC CGGCCGGGGC GCGCCACCCG TAGCTCGGTG AGGTCCGAGC TGCACGGGAA 60
AGCTTGCAGA ACGAGCGGAG AGCCGCGCGT GCGGCGGAGG TGAGCACAGG GGCGGGTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0007517--P:muscle organ development
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

KEGG

rno:691556

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001524	Ailuropoda melanoleuca	59.20	7.00e-123	433.00
IUUC-Bta-012405	Bos taurus	64.81	3.00e-121	428.00
IUUC-Cpo-022380	Cavia porcellus	66.92	3.00e-138	484.00
IUUC-Csa-023915	Chlorocebus sabaeus	74.23	2.00e-158	551.00
IUUC-Dre-027378	Danio rerio	51.69	6.00e-108	384.00
IUUC-Hsa-046421	Homo sapiens	74.70	1.00e-158	552.00
IUUC-Itr-049050	Ictidomys tridecemlineatus	77.54	1.00e-172	599.00
IUUC-Kpa-049380	Komagataella pastoris	30.51	1.50e+00	27.70
IUUC-Mcc-055433	Macaca mulatta	72.58	1.00e-154	539.00
IUUC-Mdo-062104	Monodelphis domestica	54.33	2.00e-108	385.00
IUUC-Mmu-063333	Mus musculus	94.05	0.00e+00	740.00
IUUC-Oga-088319	Otolemur garnettii	61.36	5.00e-117	414.00
IUUC-Ptr-090524	Pan troglodytes	74.94	2.00e-159	555.00
IUUC-Pan-092721	Papio anubis	63.47	6.00e-121	427.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence