iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116822

Ensembl Protein ID

ENSTGUP00000009109.1

UniProt Accession

H0ZEU7; H0ZEU7_TAEGU

Genbank Protein ID

ENSTGUP00000009109

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ABQF01012705

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000008851.1	ENSTGUT00000009207.1	ENSTGUP00000009109.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.70e-09	36.5	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MLSPANGDQL HLVNYVEDYL DSIESMPFDL QRNVSLMREI DAKYQEILKD LDDYYEKFKR 60
ETDAVQKRRM LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFETCQETN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGTC CTGCAAACGG AGACCAGCTT CACCTAGTGA ACTATGTGGA GGATTATCTG 60
GACTCCATCG AGTCTATGCC CTTCGATCTG CAGAGAAATG TCTCCTTGAT GAGGGAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	93.19	5.00e-129	452.00
IUUC-Apl-003910	Anas platyrhynchos	99.28	3.00e-137	480.00
IUUC-Aca-004874	Anolis carolinensis	94.64	6.00e-130	456.00
IUUC-Ame-011262	Astyanax mexicanus	66.55	2.00e-96	344.00
IUUC-Bta-013507	Bos taurus	89.32	3.00e-93	333.00
IUUC-Cja-018925	Callithrix jacchus	90.68	2.00e-124	438.00
IUUC-Cfa-020947	Canis familiaris	93.19	1.00e-128	451.00
IUUC-Cpo-022286	Cavia porcellus	90.68	2.00e-99	355.00
IUUC-Csa-023825	Chlorocebus sabaeus	90.32	5.00e-124	436.00
IUUC-Cho-024577	Choloepus hoffmanni	93.56	1.00e-100	358.00
IUUC-Cne-027005	Cryptococcus neoformans	47.76	6.00e-16	77.80
IUUC-Dre-028562	Danio rerio	58.09	4.00e-74	270.00
IUUC-Dno-029834	Dasypus novemcinctus	94.27	5.00e-130	456.00
IUUC-Dor-030315	Dipodomys ordii	89.74	3.00e-109	388.00
IUUC-Ete-032408	Echinops telfairi	90.64	6.00e-96	343.00
IUUC-Eca-034244	Equus caballus	93.16	1.00e-102	364.00
IUUC-Fca-035391	Felis catus	87.64	7.00e-109	385.00
IUUC-Fal-036838	Ficedula albicollis	98.92	3.00e-137	480.00
IUUC-Gmo-038748	Gadus morhua	54.51	2.00e-76	278.00
IUUC-Gga-040619	Gallus gallus	97.85	6.00e-136	476.00
IUUC-Gac-041996	Gasterosteus aculeatus	64.31	1.00e-97	348.00
IUUC-Ggo-045481	Gorilla gorilla	88.14	2.00e-97	349.00
IUUC-Hsa-046170	Homo sapiens	88.14	1.00e-97	349.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	95.30	5.00e-104	369.00
IUUC-Lch-050397	Latimeria chalumnae	89.61	4.00e-126	443.00
IUUC-Loc-052038	Lepisosteus oculatus	79.07	1.00e-99	355.00
IUUC-Laf-054126	Loxodonta africana	94.62	1.00e-130	457.00
IUUC-Mcc-055031	Macaca mulatta	88.51	4.00e-97	347.00
IUUC-Meu-056248	Macropus eugenii	94.54	5.00e-106	377.00
IUUC-Mga-059217	Meleagris gallopavo	97.00	1.00e-106	378.00
IUUC-Mmr-061581	Microcebus murinus	94.24	4.00e-108	383.00
IUUC-Mdo-062452	Monodelphis domestica	95.34	2.00e-132	464.00
IUUC-Mmu-063412	Mus musculus	92.47	2.00e-127	447.00
IUUC-Mpu-066479	Mustela putorius furo	93.16	2.00e-102	365.00
IUUC-Mlu-067586	Myotis lucifugus	79.36	8.00e-118	415.00
IUUC-Nle-069122	Nomascus leucogenys	89.96	2.00e-123	434.00
IUUC-Opr-070835	Ochotona princeps	83.26	6.00e-83	299.00
IUUC-Ont-071606	Oreochromis niloticus	61.11	1.00e-91	329.00
IUUC-Oan-073023	Ornithorhynchus anatinus	92.47	7.00e-126	442.00
IUUC-Ocu-073779	Oryctolagus cuniculus	87.08	3.00e-93	333.00
IUUC-Ola-086891	Oryzias latipes	65.71	3.00e-98	350.00
IUUC-Olu-087851	Ostreococcus lucimarinus	69.23	1.00e-19	89.40
IUUC-Oga-087954	Otolemur garnettii	91.40	5.00e-126	442.00
IUUC-Oar-090006	Ovis aries	89.96	1.00e-123	435.00
IUUC-Ptr-090589	Pan troglodytes	90.32	4.00e-124	436.00
IUUC-Pan-091896	Papio anubis	88.51	3.00e-97	348.00
IUUC-Psi-093266	Pelodiscus sinensis	96.06	3.00e-133	467.00
IUUC-Pma-094265	Petromyzon marinus	71.95	1.00e-34	138.00
IUUC-Pfo-096633	Poecilia formosa	56.44	3.00e-71	261.00
IUUC-Pab-098253	Pongo abelii	90.32	6.00e-124	436.00
IUUC-Pva-102753	Pteropus vampyrus	82.63	2.00e-91	329.00
IUUC-Rno-105964	Rattus norvegicus	91.88	1.00e-91	328.00
IUUC-Sha-107270	Sarcophilus harrisii	94.98	2.00e-131	460.00
IUUC-Tru-118262	Takifugu rubripes	56.82	2.00e-78	285.00
IUUC-Tni-119980	Tetraodon nigroviridis	58.31	6.00e-85	306.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.50
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	90.64	2.00e-99	354.00
IUUC-Xtr-132200	Xenopus tropicalis	86.38	3.00e-119	420.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence