iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059997

Ensembl Protein ID

ENSMGAP00000014876.2

UniProt Accession

G1NMQ1; G1NMQ1_MELGA

Protein Name

Uncharacterized protein

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000014061.2	ENSMGAT00000015817.2	ENSMGAP00000014876.2
ENSMGAG00000014061.2	ENSMGAT00000020385.1	ENSMGAP00000019155.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.30e-62	206.6	1127	1179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+n+deL++ kG  + v+   + d++W++g  el+g  GlfP+n+v+ 
   Q: 1127 QVIAMYDYMANNEDELSFSKGQLINVL--SKDDADWWQG--ELNGVTGLFPSNYVKM 1179
           6899***********************..8899******..9*************85 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QSLSFCVVVS GGPNIWAITA EERAKHDKQF DSLKPTGGYI TGDQARTFFL QSGLPSSVLA 60
DIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQHLPMVLP PVMKQTPVLS PLMSARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGCTC AGTTTCCCAC GGCTGTGAAT GGTGAGTAGC TCAGTTCTGG TTGCTAAGGT 60
AGGGGTGGGA GCATTTGTTT TTATTTTTTG TTGAAATGGC CCTATGAAAA AGCAGCTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	84.00	0.00e+00	1961.00
IUUC-Apl-004205	Anas platyrhynchos	91.53	0.00e+00	2236.00
IUUC-Aca-004287	Anolis carolinensis	85.34	0.00e+00	1705.00
IUUC-Ago-007935	Ashbya gossypii	32.33	5.00e-13	69.30
IUUC-Ame-011759	Astyanax mexicanus	65.77	0.00e+00	1255.00
IUUC-Bta-013248	Bos taurus	82.41	0.00e+00	1892.00
IUUC-Cel-018490	Caenorhabditis elegans	32.66	2.00e-55	210.00
IUUC-Cja-019012	Callithrix jacchus	58.38	0.00e+00	1446.00
IUUC-Cfa-020628	Canis familiaris	83.67	0.00e+00	1965.00
IUUC-Cpo-022427	Cavia porcellus	75.59	0.00e+00	1873.00
IUUC-Csa-023122	Chlorocebus sabaeus	82.11	0.00e+00	1949.00
IUUC-Cho-024969	Choloepus hoffmanni	59.94	0.00e+00	1174.00
IUUC-Cin-025435	Ciona intestinalis	43.98	0.00e+00	937.00
IUUC-Csv-026290	Ciona savignyi	54.89	0.00e+00	738.00
IUUC-Cgl-026765	Colletotrichum gloeosporioides	46.88	3.00e-13	69.30
IUUC-Cne-026918	Cryptococcus neoformans	36.07	9.00e-39	156.00
IUUC-Cme-027247	Cyanidioschyzon merolae	28.90	2.00e-11	63.50
IUUC-Dre-028623	Danio rerio	69.27	0.00e+00	1246.00
IUUC-Dno-029419	Dasypus novemcinctus	84.29	0.00e+00	1977.00
IUUC-Dor-030504	Dipodomys ordii	71.30	0.00e+00	1599.00
IUUC-Dme-032099	Drosophila melanogaster	33.05	8.00e-57	215.00
IUUC-Eca-034196	Equus caballus	80.98	0.00e+00	1870.00
IUUC-Eeu-034972	Erinaceus europaeus	63.33	4.00e-166	578.00
IUUC-Fca-035757	Felis catus	83.61	0.00e+00	1971.00
IUUC-Fal-037531	Ficedula albicollis	94.75	0.00e+00	1911.00
IUUC-Gmo-039632	Gadus morhua	53.43	0.00e+00	1273.00
IUUC-Gga-041012	Gallus gallus	93.45	0.00e+00	2202.00
IUUC-Gac-041948	Gasterosteus aculeatus	55.05	0.00e+00	1349.00
IUUC-Ggo-045405	Gorilla gorilla	79.79	0.00e+00	2377.00
IUUC-Hsa-046833	Homo sapiens	84.18	0.00e+00	1942.00
IUUC-Itr-048773	Ictidomys tridecemlineatus	55.67	0.00e+00	1360.00
IUUC-Kpa-049215	Komagataella pastoris	35.46	4.00e-15	75.90
IUUC-Lch-050094	Latimeria chalumnae	75.58	0.00e+00	1737.00
IUUC-Loc-052646	Lepisosteus oculatus	72.73	0.00e+00	1471.00
IUUC-Laf-053608	Loxodonta africana	58.15	0.00e+00	1453.00
IUUC-Mcc-054709	Macaca mulatta	83.77	0.00e+00	1956.00
IUUC-Meu-056396	Macropus eugenii	78.99	0.00e+00	1511.00
IUUC-Mvi-060268	Microbotryum violaceum	29.09	5.00e-43	170.00
IUUC-Mmr-060891	Microcebus murinus	82.24	0.00e+00	2003.00
IUUC-Mdo-062019	Monodelphis domestica	57.70	0.00e+00	1407.00
IUUC-Mmu-064226	Mus musculus	78.93	0.00e+00	1964.00
IUUC-Mpu-066431	Mustela putorius furo	81.51	0.00e+00	1947.00
IUUC-Mlu-068190	Myotis lucifugus	83.66	0.00e+00	1980.00
IUUC-Nle-070116	Nomascus leucogenys	79.96	0.00e+00	1526.00
IUUC-Opr-070815	Ochotona princeps	70.81	0.00e+00	1632.00
IUUC-Ont-071752	Oreochromis niloticus	54.81	0.00e+00	1330.00
IUUC-Oan-073390	Ornithorhynchus anatinus	56.62	0.00e+00	1354.00
IUUC-Ocu-073753	Oryctolagus cuniculus	57.59	0.00e+00	1447.00
IUUC-Ola-086482	Oryzias latipes	61.76	0.00e+00	1245.00
IUUC-Oga-088449	Otolemur garnettii	82.19	0.00e+00	1918.00
IUUC-Oar-090275	Ovis aries	82.49	0.00e+00	1923.00
IUUC-Ptr-091667	Pan troglodytes	83.76	0.00e+00	1931.00
IUUC-Pan-091723	Papio anubis	78.20	0.00e+00	1639.00
IUUC-Psi-093136	Pelodiscus sinensis	86.03	0.00e+00	2054.00
IUUC-Pfo-097486	Poecilia formosa	64.01	0.00e+00	1300.00
IUUC-Pab-098755	Pongo abelii	81.65	0.00e+00	1867.00
IUUC-Pca-101134	Procavia capensis	79.41	0.00e+00	1383.00
IUUC-Pva-102433	Pteropus vampyrus	76.19	0.00e+00	1718.00
IUUC-Pgr-103473	Puccinia graminis	30.84	2.00e-37	152.00
IUUC-Rno-105691	Rattus norvegicus	83.22	0.00e+00	2025.00
IUUC-Sha-106851	Sarcophilus harrisii	65.56	0.00e+00	1344.00
IUUC-Sar-112978	Sorex araneus	80.05	0.00e+00	1277.00
IUUC-Sre-115028	Sporisorium reilianum	35.27	4.00e-32	134.00
IUUC-Ssc-115562	Sus scrofa	74.26	0.00e+00	1741.00
IUUC-Tgu-116758	Taeniopygia guttata	91.84	0.00e+00	2212.00
IUUC-Tru-117789	Takifugu rubripes	63.71	0.00e+00	1286.00
IUUC-Tsy-119039	Tarsius syrichta	71.01	0.00e+00	1091.00
IUUC-Tni-119752	Tetraodon nigroviridis	59.33	0.00e+00	1349.00
IUUC-Ttr-129196	Tursiops truncatus	81.11	0.00e+00	1864.00
IUUC-Uma-129456	Ustilago maydis	34.98	6.00e-30	127.00
IUUC-Xtr-132905	Xenopus tropicalis	58.96	0.00e+00	1459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence