iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	miRNAMap	RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
CPLM	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-61	204.9	1092	1144

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy+a+n+deL++ kG  + v+  ++ d +W++g  e++g  GlfP+n+v+ 
   Q: 1092 QVIAMYDYMANNEDELNFSKGQLINVM--NKDDPDWWQG--ETNGLTGLFPSNYVKM 1144
           6899**********************9..8899******..9*************85 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MMAQFPTAMN GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCTGCGGA GGCCGCGGCC GCCATGTTGT TGTGGGGCTG AGGCGGCGCC GGCTGAGAGC 60
CCAGCAGCCG TGACAGGCTG CGCAACAGGT TCGCTGCGGC CGGCCTGACG ACTGACCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	86.49	0.00e+00	2091.00
IUUC-Apl-004205	Anas platyrhynchos	79.44	0.00e+00	2447.00
IUUC-Aca-004287	Anolis carolinensis	81.75	0.00e+00	1643.00
IUUC-Ame-011759	Astyanax mexicanus	64.43	0.00e+00	1244.00
IUUC-Bta-013248	Bos taurus	87.49	0.00e+00	2038.00
IUUC-Cel-018490	Caenorhabditis elegans	27.57	8.00e-54	206.00
IUUC-Cfa-020628	Canis familiaris	87.26	0.00e+00	2110.00
IUUC-Cpo-022427	Cavia porcellus	81.46	0.00e+00	2631.00
IUUC-Csa-023122	Chlorocebus sabaeus	89.10	0.00e+00	2100.00
IUUC-Cne-026918	Cryptococcus neoformans	35.31	2.00e-38	155.00
IUUC-Dre-027849	Danio rerio	63.47	0.00e+00	1196.00
IUUC-Dno-029419	Dasypus novemcinctus	89.00	0.00e+00	2115.00
IUUC-Dor-030504	Dipodomys ordii	74.49	0.00e+00	1699.00
IUUC-Dme-032099	Drosophila melanogaster	28.08	9.00e-66	245.00
IUUC-Eca-034196	Equus caballus	85.05	0.00e+00	1991.00
IUUC-Eeu-034972	Erinaceus europaeus	64.50	2.00e-174	607.00
IUUC-Fca-035757	Felis catus	87.15	0.00e+00	2098.00
IUUC-Fal-037531	Ficedula albicollis	85.31	0.00e+00	1722.00
IUUC-Gga-041012	Gallus gallus	79.40	0.00e+00	1901.00
IUUC-Ggo-045405	Gorilla gorilla	86.35	0.00e+00	2054.00
IUUC-Hsa-046833	Homo sapiens	88.40	0.00e+00	2078.00
IUUC-Lch-050094	Latimeria chalumnae	69.59	0.00e+00	1662.00
IUUC-Loc-052646	Lepisosteus oculatus	70.99	0.00e+00	1428.00
IUUC-Laf-053798	Loxodonta africana	87.77	0.00e+00	1439.00
IUUC-Mcc-054709	Macaca mulatta	88.00	0.00e+00	2098.00
IUUC-Meu-056396	Macropus eugenii	78.95	0.00e+00	1524.00
IUUC-Mla-059128	Melampsora laricipopulina	35.93	2.00e-40	162.00
IUUC-Mga-059997	Meleagris gallopavo	79.58	0.00e+00	1994.00
IUUC-Mvi-060268	Microbotryum violaceum	31.17	6.00e-47	184.00
IUUC-Mmr-060891	Microcebus murinus	89.82	0.00e+00	2146.00
IUUC-Mpu-066431	Mustela putorius furo	88.01	0.00e+00	2089.00
IUUC-Mlu-068190	Myotis lucifugus	87.25	0.00e+00	2092.00
IUUC-Nle-070116	Nomascus leucogenys	84.60	0.00e+00	1644.00
IUUC-Opr-070815	Ochotona princeps	76.80	0.00e+00	1753.00
IUUC-Ont-072464	Oreochromis niloticus	63.53	0.00e+00	1227.00
IUUC-Ola-087489	Oryzias latipes	54.27	0.00e+00	1290.00
IUUC-Oga-088449	Otolemur garnettii	86.34	0.00e+00	2031.00
IUUC-Oar-090275	Ovis aries	87.65	0.00e+00	2072.00
IUUC-Ptr-091667	Pan troglodytes	88.15	0.00e+00	2064.00
IUUC-Pan-091723	Papio anubis	90.15	0.00e+00	1820.00
IUUC-Psi-093136	Pelodiscus sinensis	77.84	0.00e+00	1901.00
IUUC-Pab-098755	Pongo abelii	86.13	0.00e+00	2004.00
IUUC-Pca-101134	Procavia capensis	82.46	0.00e+00	1456.00
IUUC-Pva-102433	Pteropus vampyrus	78.25	0.00e+00	1836.00
IUUC-Pgr-103473	Puccinia graminis	29.97	3.00e-37	152.00
IUUC-Rno-105691	Rattus norvegicus	92.20	0.00e+00	2249.00
IUUC-Sar-112978	Sorex araneus	81.13	0.00e+00	1348.00
IUUC-Sre-115028	Sporisorium reilianum	37.00	5.00e-33	137.00
IUUC-Ssc-115562	Sus scrofa	83.63	0.00e+00	1920.00
IUUC-Tgu-116758	Taeniopygia guttata	78.93	0.00e+00	1974.00
IUUC-Tru-117714	Takifugu rubripes	63.75	0.00e+00	1211.00
IUUC-Tni-119752	Tetraodon nigroviridis	57.21	0.00e+00	1316.00
IUUC-Tbe-127477	Tupaia belangeri	87.47	0.00e+00	736.00
IUUC-Ttr-129196	Tursiops truncatus	85.34	0.00e+00	1998.00
IUUC-Uma-129456	Ustilago maydis	32.68	1.00e-32	136.00
IUUC-Vpa-130035	Vicugna pacos	78.04	1.00e-177	617.00
IUUC-Xma-133300	Xiphophorus maculatus	59.21	0.00e+00	1335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence