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Tag Content
iUUCD ID IUUC-Fca-036013
Ensembl Protein ID ENSFCAP00000019634.1
UniProt Accession M3WZ44; M3WZ44_FELCA
Genbank Protein ID ENSFCAP00000019634
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AANG02151257
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000023180.1 ENSFCAT00000029357.1 ENSFCAP00000019634.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.60e-114 381.9 186 715
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+
   Q: 186  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGGLARTDKKPAICKSYLKLMTELWhKSRPGSVVPTTLFQGIKTVNPTFRGYS 269
           7******************************.....999999*******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde........................................ 129
           qqDaqEfl++l+d l+eelk+         ++ ++ee++eedks+++ +                                        
   Q: 270  QQDAQEFLRCLMDLLHEELKEqvmeveedPQTITTEETMEEDKSQSDVDfqscescsssdkaenengskvfsednnettmliqddenns 358
           *******************8899998887777777777788877777779*************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 359  emskdwqkekmcnkinkvnsegeldkdrdsvsetvdlnnqetvkvqihsraseyitdvhlndlstsqilpsnegvnprlsasppksgnl 447
           ***************************************************************************************** PP
   S: 130  ................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke................. 185
                           +eek++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+                 
   Q: 448  wpglapthkkgrsfsySEEKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhssshptsivkagscge 536
           *******************************************************************99888***************** PP
   S: 186  ................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfsee 242
                                           +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L++hLkRf  ++e
   Q: 537  ayapqgwiaffmeyvkrfvvscvpswfwgpvvTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF--RHE 623
           ************************************************************************************..999 PP
   S: 243  qksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgst 329
            ++++ki+++v+fple Ldl+pf+++++  q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v++   ++
   Q: 624  LMFSTKISTHVSFPLEgLDLQPFLAKDSPVQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEVSESTVQN---AE 707
           9*************************77776..9**************************88889*******************...** PP
   S: 330  aYvlfYkr 337
           aYvlfY++
   Q: 708  AYVLFYRK 715
           ******98 PP
   
Organism Felis catus
Protein Sequence
(Fasta)
LMGERVHYAS LLLEVLPHLE ILGRQEKVTN KMSPFQNHCP HLDSVGEITK EDLMQKSHSF 60
SKSLNIYIHI YIYICIYNRC SYVGCGESQV DHSTIHSQET KHYLTVNLTT LRVWCYACSK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fca-036013|DUB,USP|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCATGGGAG AGAGAGGTAT GAGACCTTAC TGGTCATCTA AAAAGAAGTA CATAAAGGGA 60
TGCTGCAGAG TGCCTAATAA AATTATATGG ATATGTGTAG TACTATGTGT GTGTATGTAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-036013|DUB,USP|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001742 Ailuropoda melanoleuca 94.50 0.00e+00 1767.00
IUUC-Apl-003987 Anas platyrhynchos 80.48 0.00e+00 1434.00
IUUC-Aca-004713 Anolis carolinensis 75.55 0.00e+00 1365.00
IUUC-Bta-013132 Bos taurus 94.75 0.00e+00 1715.00
IUUC-Cja-018811 Callithrix jacchus 93.69 0.00e+00 1743.00
IUUC-Cfa-021158 Canis familiaris 93.67 0.00e+00 1762.00
IUUC-Cpo-021910 Cavia porcellus 86.76 0.00e+00 1518.00
IUUC-Csa-023130 Chlorocebus sabaeus 94.53 0.00e+00 1715.00
IUUC-Cho-024383 Choloepus hoffmanni 74.07 5.00e-176 611.00
IUUC-Dre-028639 Danio rerio 68.57 0.00e+00 1196.00
IUUC-Dno-029416 Dasypus novemcinctus 92.02 0.00e+00 1659.00
IUUC-Ete-032994 Echinops telfairi 77.66 0.00e+00 842.00
IUUC-Eca-034248 Equus caballus 93.88 0.00e+00 1739.00
IUUC-Eeu-035357 Erinaceus europaeus 80.22 0.00e+00 1212.00
IUUC-Fal-037509 Ficedula albicollis 80.22 0.00e+00 1430.00
IUUC-Gmo-038944 Gadus morhua 64.28 0.00e+00 1135.00
IUUC-Gga-040647 Gallus gallus 79.69 0.00e+00 1408.00
IUUC-Gac-041752 Gasterosteus aculeatus 67.86 0.00e+00 1200.00
IUUC-Hsa-045694 Homo sapiens 93.02 0.00e+00 1742.00
IUUC-Itr-049041 Ictidomys tridecemlineatus 93.88 0.00e+00 1690.00
IUUC-Kpa-049198 Komagataella pastoris 32.67 4.00e-27 116.00
IUUC-Lch-050400 Latimeria chalumnae 69.27 0.00e+00 1228.00
IUUC-Loc-052616 Lepisosteus oculatus 69.03 0.00e+00 1284.00
IUUC-Laf-053493 Loxodonta africana 93.11 0.00e+00 1696.00
IUUC-Mcc-055542 Macaca mulatta 94.21 0.00e+00 1747.00
IUUC-Meu-056645 Macropus eugenii 72.89 0.00e+00 1282.00
IUUC-Mga-060019 Meleagris gallopavo 82.38 0.00e+00 1253.00
IUUC-Mmr-061241 Microcebus murinus 90.33 0.00e+00 1688.00
IUUC-Mmu-063786 Mus musculus 90.48 0.00e+00 1623.00
IUUC-Mpu-065772 Mustela putorius furo 96.93 0.00e+00 1468.00
IUUC-Mlu-067732 Myotis lucifugus 91.42 0.00e+00 1704.00
IUUC-Nle-069528 Nomascus leucogenys 93.33 0.00e+00 1721.00
IUUC-Opr-070606 Ochotona princeps 87.76 0.00e+00 1529.00
IUUC-Ont-071495 Oreochromis niloticus 69.00 0.00e+00 1208.00
IUUC-Oan-073695 Ornithorhynchus anatinus 82.09 0.00e+00 984.00
IUUC-Ocu-074457 Oryctolagus cuniculus 90.78 0.00e+00 1651.00
IUUC-Ola-086739 Oryzias latipes 67.88 0.00e+00 1252.00
IUUC-Oga-088720 Otolemur garnettii 91.85 0.00e+00 1732.00
IUUC-Oar-089921 Ovis aries 93.68 0.00e+00 1737.00
IUUC-Ptr-090526 Pan troglodytes 93.90 0.00e+00 1741.00
IUUC-Pan-092396 Papio anubis 93.60 0.00e+00 1737.00
IUUC-Psi-092971 Pelodiscus sinensis 81.13 0.00e+00 1498.00
IUUC-Pfo-097415 Poecilia formosa 67.65 0.00e+00 1207.00
IUUC-Pab-098740 Pongo abelii 94.42 0.00e+00 1738.00
IUUC-Pca-100598 Procavia capensis 83.90 0.00e+00 908.00
IUUC-Pva-102820 Pteropus vampyrus 89.65 0.00e+00 1450.00
IUUC-Rno-104894 Rattus norvegicus 90.05 0.00e+00 1633.00
IUUC-Sha-107244 Sarcophilus harrisii 75.16 0.00e+00 1330.00
IUUC-Sar-113665 Sorex araneus 90.77 0.00e+00 1702.00
IUUC-Ssc-115793 Sus scrofa 91.59 0.00e+00 1631.00
IUUC-Tgu-117487 Taeniopygia guttata 81.17 0.00e+00 1402.00
IUUC-Tru-117694 Takifugu rubripes 67.24 0.00e+00 1220.00
IUUC-Tsy-119598 Tarsius syrichta 81.55 0.00e+00 1425.00
IUUC-Tni-120189 Tetraodon nigroviridis 64.57 0.00e+00 1154.00
IUUC-Tbe-128125 Tupaia belangeri 77.43 9.00e-103 368.00
IUUC-Ttr-128269 Tursiops truncatus 90.33 0.00e+00 1602.00
IUUC-Vpa-130598 Vicugna pacos 91.21 0.00e+00 1675.00
IUUC-Xtr-132044 Xenopus tropicalis 72.96 0.00e+00 1262.00
Created Date 25-Jun-2017

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