iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116311

Ensembl Protein ID

ENSSSCP00000012323.2

UniProt Accession

F1SQC5; F1SQC5_PIG

Genbank Protein ID

ENSSSCP00000012323

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU464019

Gene Name

FANCD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011563.2	ENSSSCT00000012655.2	ENSSSCP00000012323.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/CUE	1.10e-08	35.2	191	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFP.nldysviqvvLeantgsleaavnnLLegs 43
           dl+t+++qL++i+P  l+++ i +++e++++s++a+v+++L+++
   Q: 191  DLTTKIMQLISIAPvYLQHDFIISLPEILGDSQHADVGKELSDL 234
           79***************************************986 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MVSKRRQSRS EDKESLTEDA SETRKQPLSK KTKKFHVHNE VEENDSVFVK LLKTAGLILK 60
TGESQNQLAV DQIVFQKKLF QTLRKHPSYP KIIEEFVSGL ESYIEDQGSF RNCLLSCERL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCGCTCC GGTGGCGTTG GCGTGGCGGC GTGCGGGGCG GGAAAGTCGA AACCTAGGGC 60
GGTGACTTCT TGGCGGGTAA GTGGAGCAGC GGTCATTGTC CCTCGAGGTC CCTTGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR029448--FANCD2

Pfam

PF14631--FancD2

Gene Ontology

GO:0000793--C:condensed chromosome
GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0070182--F:DNA polymerase binding
GO:0048854--P:brain morphogenesis
GO:0034599--P:cellular response to oxidative stress
GO:0006281--P:DNA repair
GO:0007276--P:gamete generation
GO:0097150--P:neuronal stem cell population maintenance
GO:2000348--P:regulation of CD40 signaling pathway
GO:0050727--P:regulation of inflammatory response
GO:0045589--P:regulation of regulatory T cell differentiation
GO:0051090--P:regulation of sequence-specific DNA binding transcription factor activity
GO:0010332--P:response to gamma radiation
GO:0007129--P:synapsis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000432	Aegilops tauschii	30.98	5.00e-64	239.00
IUUC-Aml-001335	Ailuropoda melanoleuca	87.21	0.00e+00	2420.00
IUUC-Atr-002827	Amborella trichopoda	30.77	8.80e-01	28.10
IUUC-Apl-004194	Anas platyrhynchos	54.07	0.00e+00	1441.00
IUUC-Aca-004342	Anolis carolinensis	56.47	0.00e+00	1529.00
IUUC-Aly-005786	Arabidopsis lyrata	26.43	2.00e-62	234.00
IUUC-Ath-007464	Arabidopsis thaliana	27.86	5.00e-77	283.00
IUUC-Ame-011928	Astyanax mexicanus	53.93	0.00e+00	713.00
IUUC-Bta-012694	Bos taurus	84.01	0.00e+00	2336.00
IUUC-Bdi-014978	Brachypodium distachyon	28.88	2.00e-70	261.00
IUUC-Cel-018414	Caenorhabditis elegans	24.75	9.00e-07	49.70
IUUC-Cja-018718	Callithrix jacchus	81.55	0.00e+00	2343.00
IUUC-Cfa-020099	Canis familiaris	86.53	0.00e+00	2392.00
IUUC-Cpo-022409	Cavia porcellus	76.66	0.00e+00	2060.00
IUUC-Csa-023529	Chlorocebus sabaeus	81.21	0.00e+00	2310.00
IUUC-Cho-024646	Choloepus hoffmanni	77.91	0.00e+00	877.00
IUUC-Cin-025320	Ciona intestinalis	25.90	3.00e-60	227.00
IUUC-Csv-025936	Ciona savignyi	36.92	3.00e-05	40.80
IUUC-Cme-027121	Cyanidioschyzon merolae	31.08	4.00e-15	77.40
IUUC-Dre-027518	Danio rerio	53.51	0.00e+00	1382.00
IUUC-Dno-029719	Dasypus novemcinctus	81.86	0.00e+00	2268.00
IUUC-Dme-032205	Drosophila melanogaster	23.59	6.00e-56	213.00
IUUC-Ete-032735	Echinops telfairi	59.42	0.00e+00	1079.00
IUUC-Eca-033657	Equus caballus	86.35	0.00e+00	2378.00
IUUC-Eeu-035133	Erinaceus europaeus	64.83	0.00e+00	1704.00
IUUC-Fca-035880	Felis catus	80.29	0.00e+00	2246.00
IUUC-Fal-037013	Ficedula albicollis	53.16	0.00e+00	1285.00
IUUC-Gmo-039371	Gadus morhua	48.99	0.00e+00	711.00
IUUC-Gga-040720	Gallus gallus	55.71	0.00e+00	1464.00
IUUC-Gac-042331	Gasterosteus aculeatus	52.00	0.00e+00	1292.00
IUUC-Ggo-045657	Gorilla gorilla	76.79	0.00e+00	2161.00
IUUC-Hsa-046759	Homo sapiens	83.95	0.00e+00	2397.00
IUUC-Hvu-047390	Hordeum vulgare	29.74	9.00e-69	255.00
IUUC-Itr-048885	Ictidomys tridecemlineatus	79.51	0.00e+00	2274.00
IUUC-Lch-049711	Latimeria chalumnae	55.75	0.00e+00	1484.00
IUUC-Lpe-050891	Leersia perrieri	25.75	7.00e-94	338.00
IUUC-Loc-051888	Lepisosteus oculatus	53.43	0.00e+00	1387.00
IUUC-Laf-053492	Loxodonta africana	82.16	0.00e+00	2312.00
IUUC-Mcc-055632	Macaca mulatta	81.19	0.00e+00	2311.00
IUUC-Mga-059769	Meleagris gallopavo	53.95	0.00e+00	1420.00
IUUC-Mmr-061234	Microcebus murinus	84.28	0.00e+00	2413.00
IUUC-Mdo-062903	Monodelphis domestica	69.97	0.00e+00	1941.00
IUUC-Mmu-063676	Mus musculus	73.27	0.00e+00	1975.00
IUUC-Mpu-066421	Mustela putorius furo	85.28	0.00e+00	2056.00
IUUC-Mlu-067851	Myotis lucifugus	81.45	0.00e+00	2277.00
IUUC-Nle-069694	Nomascus leucogenys	84.39	0.00e+00	1106.00
IUUC-Opr-071174	Ochotona princeps	66.77	0.00e+00	1137.00
IUUC-Ont-071414	Oreochromis niloticus	51.87	0.00e+00	1331.00
IUUC-Oan-072704	Ornithorhynchus anatinus	54.28	4.00e-82	297.00
IUUC-Ocu-073877	Oryctolagus cuniculus	77.88	0.00e+00	2183.00
IUUC-Obr-076418	Oryza brachyantha	25.55	6.00e-94	339.00
IUUC-Ogl-077563	Oryza glaberrima	25.17	8.00e-58	218.00
IUUC-Ogu-077998	Oryza glumaepatula	25.33	7.00e-97	348.00
IUUC-Olo-080953	Oryza longistaminata	24.35	7.00e-83	302.00
IUUC-Ome-081590	Oryza meridionalis	25.60	1.00e-98	354.00
IUUC-Opu-083761	Oryza punctata	25.65	3.00e-96	346.00
IUUC-Oru-084791	Oryza rufipogon	25.52	6.00e-97	349.00
IUUC-Osa-085771	Oryza sativa	25.49	4.00e-67	249.00
IUUC-Ola-086402	Oryzias latipes	50.64	0.00e+00	1329.00
IUUC-Oga-088325	Otolemur garnettii	79.97	0.00e+00	2170.00
IUUC-Oar-089492	Ovis aries	85.42	0.00e+00	2402.00
IUUC-Ptr-091257	Pan troglodytes	84.41	0.00e+00	2400.00
IUUC-Pan-091710	Papio anubis	89.00	0.00e+00	762.00
IUUC-Psi-093960	Pelodiscus sinensis	55.93	0.00e+00	1217.00
IUUC-Pma-094600	Petromyzon marinus	47.68	0.00e+00	1186.00
IUUC-Ppa-095666	Physcomitrella patens	27.76	4.00e-82	300.00
IUUC-Pfo-096345	Poecilia formosa	51.97	0.00e+00	1340.00
IUUC-Pab-098684	Pongo abelii	79.71	0.00e+00	2301.00
IUUC-Pca-100659	Procavia capensis	64.02	0.00e+00	1210.00
IUUC-Pva-102653	Pteropus vampyrus	82.73	0.00e+00	2316.00
IUUC-Pte-104328	Pyrenophora teres	30.00	3.60e-01	28.90
IUUC-Rno-105830	Rattus norvegicus	73.14	0.00e+00	2030.00
IUUC-Sha-106852	Sarcophilus harrisii	70.15	0.00e+00	1882.00
IUUC-Sit-110198	Setaria italica	24.04	2.00e-85	311.00
IUUC-Sar-113565	Sorex araneus	59.27	0.00e+00	930.00
IUUC-Tgu-116706	Taeniopygia guttata	53.94	0.00e+00	1419.00
IUUC-Tru-118512	Takifugu rubripes	50.67	0.00e+00	1268.00
IUUC-Tni-120565	Tetraodon nigroviridis	51.47	0.00e+00	1319.00
IUUC-Tca-121195	Theobroma cacao	29.07	2.00e-78	287.00
IUUC-Tbe-127657	Tupaia belangeri	73.63	0.00e+00	1139.00
IUUC-Ttr-128431	Tursiops truncatus	84.69	0.00e+00	2346.00
IUUC-Vpa-130299	Vicugna pacos	79.66	0.00e+00	1225.00
IUUC-Vvi-131258	Vitis vinifera	28.95	7.00e-39	155.00
IUUC-Xtr-132684	Xenopus tropicalis	56.88	0.00e+00	1535.00
IUUC-Xma-133655	Xiphophorus maculatus	52.52	0.00e+00	1301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence