iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004533

UUCD1 version

UUC-AnC-00508

Ensembl Protein ID

ENSACAP00000003113.3

UniProt Accession

G1KBN2; G1KBN2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003203.3	ENSACAT00000003192.3	ENSACAP00000003113.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.30e-47	162.9	39	231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t l+ C+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv +++++ y++l++e++v+ d+ +
   Q: 39   CKLCLSEYSLDKMTSLQDCSCIFCTSCLKQYMQLAIREGCGSPITCPDMVCLSRgtLQETEISS-LVPADQFQLYQRLKFEREVHLDPLR 127
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekeaekleve..cekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+++e ++++l v+  c++c  +fC++Cke wH ++sC e +  +  +e   + a   + ++a +k+Cp C++ ie+neg
   Q: 128  TWCPSADCQTVCQIELSESELPVPvkCQACYLTFCSSCKEPWHLDRSCLESHLLVVPNE---QGALIRTDTDAPIKQCPICRIHIERNEG 214
           **************998876665555**********************99988888887...8899999********************* PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 215  CAQMMCKNCKHTFCWYC 231
           ***************** PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MMTTDLVKLM ASPGKICHSI MMTGISEVGE LSLEPLVTCK LCLSEYSLDK MTSLQDCSCI 60
FCTSCLKQYM QLAIREGCGS PITCPDMVCL SRGTLQETEI SSLVPADQFQ LYQRLKFERE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCGTTCTA AAGAGCCAAG GCAGTTGTGG TATAGATCAG CGAGGCTTGG GGAGGGTTAA 60
AAATAATCAC CTGCAGTTGA AATGAGACGT GGGAAGTAGG AAGTGCTGCA GCTTAAGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	76.90	2.00e-138	484.00
IUUC-Apl-004112	Anas platyrhynchos	80.07	5.00e-128	450.00
IUUC-Bta-012641	Bos taurus	77.05	1.00e-137	482.00
IUUC-Cja-019626	Callithrix jacchus	69.41	2.00e-117	414.00
IUUC-Cfa-020702	Canis familiaris	75.91	3.00e-136	477.00
IUUC-Cpo-022147	Cavia porcellus	76.90	1.00e-136	478.00
IUUC-Csa-023473	Chlorocebus sabaeus	75.91	8.00e-137	479.00
IUUC-Cho-024298	Choloepus hoffmanni	71.98	2.00e-110	391.00
IUUC-Dre-028099	Danio rerio	63.16	4.00e-93	333.00
IUUC-Dno-029122	Dasypus novemcinctus	73.20	1.00e-129	455.00
IUUC-Dor-030669	Dipodomys ordii	80.26	1.00e-111	395.00
IUUC-Ete-033141	Echinops telfairi	67.11	9.00e-104	369.00
IUUC-Eca-034360	Equus caballus	78.22	3.00e-140	490.00
IUUC-Eeu-034538	Erinaceus europaeus	66.20	2.00e-77	281.00
IUUC-Fca-036055	Felis catus	76.57	3.00e-136	477.00
IUUC-Fal-037339	Ficedula albicollis	79.57	2.00e-132	464.00
IUUC-Gmo-038780	Gadus morhua	61.99	4.00e-87	313.00
IUUC-Gga-040256	Gallus gallus	78.29	2.00e-129	454.00
IUUC-Gac-042127	Gasterosteus aculeatus	60.82	7.00e-93	333.00
IUUC-Ggo-044867	Gorilla gorilla	76.57	2.00e-137	481.00
IUUC-Hsa-046928	Homo sapiens	76.57	2.00e-137	481.00
IUUC-Hvu-047484	Hordeum vulgare	29.29	2.00e-18	86.70
IUUC-Itr-048250	Ictidomys tridecemlineatus	80.83	4.00e-92	329.00
IUUC-Lch-050168	Latimeria chalumnae	71.80	5.00e-131	459.00
IUUC-Lpe-051649	Leersia perrieri	27.94	5.00e-17	83.20
IUUC-Loc-052150	Lepisosteus oculatus	58.61	4.00e-85	307.00
IUUC-Laf-053967	Loxodonta africana	76.90	2.00e-138	484.00
IUUC-Mcc-055898	Macaca mulatta	75.91	8.00e-137	479.00
IUUC-Meu-056628	Macropus eugenii	89.74	2.00e-41	162.00
IUUC-Mga-059820	Meleagris gallopavo	77.94	2.00e-129	454.00
IUUC-Mmr-060680	Microcebus murinus	77.56	4.00e-137	480.00
IUUC-Mdo-062839	Monodelphis domestica	78.95	3.00e-142	497.00
IUUC-Mmu-063339	Mus musculus	79.93	3.00e-123	434.00
IUUC-Mac-065414	Musa acuminata	29.38	1.00e-17	84.00
IUUC-Mpu-065973	Mustela putorius furo	74.60	1.00e-137	482.00
IUUC-Mlu-067112	Myotis lucifugus	76.24	9.00e-128	449.00
IUUC-Nle-069795	Nomascus leucogenys	76.39	4.00e-138	483.00
IUUC-Opr-070390	Ochotona princeps	71.05	1.00e-120	425.00
IUUC-Ont-072329	Oreochromis niloticus	59.09	3.00e-89	321.00
IUUC-Oan-072980	Ornithorhynchus anatinus	72.73	8.00e-130	456.00
IUUC-Ocu-073845	Oryctolagus cuniculus	76.57	2.00e-136	477.00
IUUC-Ola-086872	Oryzias latipes	61.42	1.00e-85	308.00
IUUC-Oga-088954	Otolemur garnettii	75.58	4.00e-136	476.00
IUUC-Oar-089879	Ovis aries	76.39	9.00e-137	479.00
IUUC-Ptr-090685	Pan troglodytes	76.57	2.00e-137	481.00
IUUC-Pan-092086	Papio anubis	76.24	6.00e-137	479.00
IUUC-Psi-093481	Pelodiscus sinensis	78.55	1.00e-134	471.00
IUUC-Pfo-096065	Poecilia formosa	62.50	7.00e-90	323.00
IUUC-Pab-098031	Pongo abelii	76.24	2.00e-136	478.00
IUUC-Pca-100936	Procavia capensis	77.30	4.00e-137	480.00
IUUC-Pva-102864	Pteropus vampyrus	66.67	2.00e-114	405.00
IUUC-Rno-105503	Rattus norvegicus	79.23	1.00e-122	432.00
IUUC-Sha-107425	Sarcophilus harrisii	79.61	2.00e-142	498.00
IUUC-Ssc-115458	Sus scrofa	76.30	2.00e-125	441.00
IUUC-Tgu-117226	Taeniopygia guttata	78.85	1.00e-131	461.00
IUUC-Tru-118362	Takifugu rubripes	60.29	1.00e-90	326.00
IUUC-Tsy-119255	Tarsius syrichta	77.63	4.00e-138	483.00
IUUC-Tni-120140	Tetraodon nigroviridis	58.61	8.00e-86	309.00
IUUC-Tae-124420	Triticum aestivum	29.80	2.00e-19	90.50
IUUC-Tbe-127306	Tupaia belangeri	76.97	1.00e-136	478.00
IUUC-Ttr-128923	Tursiops truncatus	76.39	2.00e-124	438.00
IUUC-Vpa-130148	Vicugna pacos	76.64	7.00e-136	476.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence