iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013118

Ensembl Protein ID

ENSBTAP00000025375.5

UniProt Accession

E1BA85; E1BA85_BOVIN

Genbank Protein ID

ENSBTAP00000025375

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02041019

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000019059.5	ENSBTAT00000025375.5	ENSBTAP00000025375.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-27	95.1	332	365
UBD/Beta-Prp	5.60e-46	157.2	330	615

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H ++v++++f ++  ll++G+ D  i +W++  g
   Q: 332  HLSEVSAVRFgPNsSLLATGGADRLILLWNVVGG 365
           99*********7779***************8665 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v f p++sllatg++d+ i +w+v  g l   ++l+g  + +t+v+f+p+g+ l+ +   +++++w +   +   tl+gh
   Q: 330  DAHLSEVSAVRFGPNSSLLATGGADRLILLWNVVGGHLkaNQTLEGAGGSITSVDFDPSGSQLLAATYNKAAQLWKVGEAQSKETLSGH 418
           67889999****************************9988899********************************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 419  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLCRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPRCTQVIP--VQGR 501
           ************************************9.666655...5555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iW++++g+l ++l +++s 
   Q: 502  VTSLSLSHDQLHLLSCSRDDTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSWDGALYIWNVDTGKLESSLRGPHSA 589
           ****************************888833334444555556666.8899*********************************99 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   ++++++n++v++++  kv +w
   Q: 590  AVNAVAWCYSGNHVVSVDQARKVVLW 615
           999999*************99*9999 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MEGPGVLGAP AARWKRHIVR QLRQRDRTQK ALFLELVPAY NRLLEKAELL ARFSEELQPE 60
PDDVTLSVHQ GPWEKESHQG LSPAALRVKW QEEVEGLRLV CGEMAYQVVE KSATLGTLES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAGGGCG GCCATGGAGG GGCCCGGCGT CCTCGGCGCC CCCGCCGCCC GCTGGAAGCG 60
CCACATCGTG CGGCAGCTTC GACAGCGGGA TCGAACGCAA AAGGCCCTAT TCCTGGAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR013829--Hemagglutn_stalk
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005654--C:nucleoplasm
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

KEGG

bta:511036

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	68.48	0.00e+00	759.00
IUUC-Atr-003073	Amborella trichopoda	32.34	8.00e-28	118.00
IUUC-Ame-011152	Astyanax mexicanus	42.57	7.00e-117	414.00
IUUC-Cja-020002	Callithrix jacchus	83.55	0.00e+00	915.00
IUUC-Cfa-020878	Canis familiaris	82.92	0.00e+00	913.00
IUUC-Cpo-022476	Cavia porcellus	80.68	0.00e+00	879.00
IUUC-Csa-024134	Chlorocebus sabaeus	84.54	0.00e+00	926.00
IUUC-Cho-024853	Choloepus hoffmanni	69.84	9.00e-176	609.00
IUUC-Dre-027949	Danio rerio	42.57	1.00e-127	450.00
IUUC-Dno-029683	Dasypus novemcinctus	84.69	0.00e+00	777.00
IUUC-Dor-030897	Dipodomys ordii	77.51	0.00e+00	909.00
IUUC-Ete-032957	Echinops telfairi	93.20	4.00e-130	458.00
IUUC-Eca-033303	Equus caballus	91.67	4.00e-166	577.00
IUUC-Eeu-035336	Erinaceus europaeus	75.43	2.00e-155	542.00
IUUC-Fca-036232	Felis catus	85.32	0.00e+00	999.00
IUUC-Gmo-038880	Gadus morhua	51.40	2.00e-71	263.00
IUUC-Gac-042500	Gasterosteus aculeatus	41.15	2.00e-90	327.00
IUUC-Ggo-045130	Gorilla gorilla	89.60	0.00e+00	684.00
IUUC-Hsa-046359	Homo sapiens	85.83	0.00e+00	903.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	81.97	0.00e+00	922.00
IUUC-Lch-050669	Latimeria chalumnae	51.96	2.00e-96	345.00
IUUC-Loc-052789	Lepisosteus oculatus	43.00	6.00e-116	411.00
IUUC-Laf-053699	Loxodonta africana	84.32	0.00e+00	922.00
IUUC-Mcc-055657	Macaca mulatta	80.13	0.00e+00	836.00
IUUC-Meu-056639	Macropus eugenii	50.39	4.00e-110	392.00
IUUC-Mmr-061314	Microcebus murinus	78.78	0.00e+00	835.00
IUUC-Mdo-061841	Monodelphis domestica	65.81	0.00e+00	703.00
IUUC-Mmu-064065	Mus musculus	80.59	0.00e+00	925.00
IUUC-Mac-065022	Musa acuminata	32.39	1.00e-40	160.00
IUUC-Mpu-066742	Mustela putorius furo	83.84	0.00e+00	913.00
IUUC-Mlu-067019	Myotis lucifugus	87.84	0.00e+00	676.00
IUUC-Nle-069037	Nomascus leucogenys	86.00	0.00e+00	941.00
IUUC-Opr-071039	Ochotona princeps	80.88	0.00e+00	892.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.60	1.00e-137	482.00
IUUC-Ocu-074772	Oryctolagus cuniculus	82.88	0.00e+00	828.00
IUUC-Ola-086964	Oryzias latipes	52.61	1.00e-83	302.00
IUUC-Oga-088188	Otolemur garnettii	81.91	0.00e+00	852.00
IUUC-Oar-090231	Ovis aries	89.09	0.00e+00	1056.00
IUUC-Ptr-091434	Pan troglodytes	83.09	0.00e+00	858.00
IUUC-Pan-091868	Papio anubis	85.14	0.00e+00	917.00
IUUC-Psi-093652	Pelodiscus sinensis	64.50	8.00e-166	576.00
IUUC-Pfo-096960	Poecilia formosa	42.48	3.00e-100	359.00
IUUC-Pab-097776	Pongo abelii	85.01	0.00e+00	856.00
IUUC-Pca-100220	Procavia capensis	65.27	1.00e-177	616.00
IUUC-Ppe-101790	Prunus persica	31.45	8.00e-45	174.00
IUUC-Pva-103135	Pteropus vampyrus	86.66	0.00e+00	877.00
IUUC-Rno-105529	Rattus norvegicus	79.45	0.00e+00	948.00
IUUC-Sha-107062	Sarcophilus harrisii	66.99	0.00e+00	745.00
IUUC-Sar-113109	Sorex araneus	66.75	4.00e-133	468.00
IUUC-Sbi-114819	Sorghum bicolor	33.45	1.00e-38	154.00
IUUC-Ssc-115271	Sus scrofa	87.44	0.00e+00	931.00
IUUC-Ttr-128267	Tursiops truncatus	84.81	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence