iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107062

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01120054

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005731.1	ENSSHAT00000006642.1	ENSSHAP00000006585.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-29	101.3	334	369
UBD/Beta-Prp	1.30e-50	172.4	329	618

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f s+  ll++G+ D  i++W++  g+l
   Q: 334  HRSEVNAVCFsSNsSLLATGGADRLIRLWNVVGGRL 369
           9*********96669***************987765 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
            ++++h s +++v+fs ++sllatg++d+ i++w+v  g l   + l+g  + vt+++f+p+g +l+ +   +++++w +  ++   tl
   Q: 329  DIQEAHRSEVNAVCFSSNSSLLATGGADRLIRLWNVVGGRLeaDQMLEGAGGSVTSLEFEPSGCYLLAATYNKAAQLWKVGESQSKETL 417
           689**************************************6445679999************************************** PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           +gh+d+v++ +f  +++  v+Gs+drt++ wdl++ +c++      dgv  c  v + + l++sG++D+++r+Wd++  ++++      
   Q: 418  SGHTDKVTAAKFKLTRQQAVTGSRDRTVKEWDLNKVSCSR----TIDGVSYCNDVVCGDHLIISGHNDQKIRFWDSRVPRCIQVIP--V 500
           ***************************************8....6677777888888778*************************6..5 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           +++v+sls++s++ +l+s+s+d  +k+ dl+++++ + +++       d++k   fsp++++ + gs+Dg ++iW+l+sg+l ++l ++
   Q: 501  EGRVTSLSISSDQLHLLSCSRDDALKVIDLRANNIRQVFRADGfkcgsDWTK-AVFSPDKNFALAGSADGGLYIWNLDSGKLETSLYGP 588
           99*****************************999955555544555526666.8899******************************** PP
   S: 264  nssvisvavlsfgdnvlvlgsedskvniwk 293
           +s +i   +++  + ++v++++ +k+ +w+
   Q: 589  HSVSINAVAWCCAGTHVVSVDQGKKAVLWS 618
           *999999999************99999995 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MPGPGTLAPR SPLPSSCRWK LHIIRQLQQR DRRQKALFLD LVEAYHRLLE KSDLLAHITE 60
KLPPEPPSEL VHLPSGEEEK ARPVLDSAQS PEDLRRKWEE EVDKVKLVCG EMAYQVVEKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCCGTC CCTCAGGCCT TGGTCGGCGA AGCTTTTGTG CCTGTTGGGC GGGCGGGCGG 60
AGGGAGCGAA TCGGTGCCTT TGGGAGCGCG GGCCGCCATG CCAGGACCCG GGACTCTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

KEGG

shr:100926478

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	55.56	2.00e-170	592.00
IUUC-Ame-011152	Astyanax mexicanus	41.67	8.00e-115	407.00
IUUC-Bta-013118	Bos taurus	66.99	0.00e+00	710.00
IUUC-Cja-020002	Callithrix jacchus	64.75	0.00e+00	695.00
IUUC-Cfa-020878	Canis familiaris	60.99	0.00e+00	669.00
IUUC-Cpo-022476	Cavia porcellus	64.02	0.00e+00	686.00
IUUC-Csa-024134	Chlorocebus sabaeus	63.29	0.00e+00	680.00
IUUC-Cho-024853	Choloepus hoffmanni	56.92	2.00e-148	518.00
IUUC-Dre-027949	Danio rerio	42.69	7.00e-126	444.00
IUUC-Dno-029683	Dasypus novemcinctus	66.41	0.00e+00	656.00
IUUC-Dor-030897	Dipodomys ordii	60.78	0.00e+00	688.00
IUUC-Ete-032957	Echinops telfairi	80.00	1.00e-112	400.00
IUUC-Eca-033303	Equus caballus	77.40	1.00e-139	489.00
IUUC-Eeu-035336	Erinaceus europaeus	61.19	3.00e-128	451.00
IUUC-Fca-036232	Felis catus	64.75	0.00e+00	729.00
IUUC-Gmo-038880	Gadus morhua	54.01	1.00e-72	267.00
IUUC-Gac-042500	Gasterosteus aculeatus	45.45	4.00e-87	315.00
IUUC-Ggo-045130	Gorilla gorilla	68.38	3.00e-163	568.00
IUUC-Hsa-046359	Homo sapiens	64.31	0.00e+00	671.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	64.75	0.00e+00	703.00
IUUC-Lch-050669	Latimeria chalumnae	54.52	3.00e-95	341.00
IUUC-Loc-052789	Lepisosteus oculatus	44.08	9.00e-117	413.00
IUUC-Laf-053699	Loxodonta africana	65.18	0.00e+00	695.00
IUUC-Mcc-055657	Macaca mulatta	59.84	2.00e-176	611.00
IUUC-Meu-056639	Macropus eugenii	65.89	7.00e-166	577.00
IUUC-Mmr-061314	Microcebus murinus	60.93	9.00e-179	619.00
IUUC-Mdo-061841	Monodelphis domestica	84.49	0.00e+00	940.00
IUUC-Mmu-064065	Mus musculus	65.25	0.00e+00	740.00
IUUC-Mpu-066742	Mustela putorius furo	64.43	0.00e+00	697.00
IUUC-Mlu-067019	Myotis lucifugus	72.28	3.00e-159	555.00
IUUC-Nle-069037	Nomascus leucogenys	64.14	0.00e+00	698.00
IUUC-Opr-071039	Ochotona princeps	65.38	0.00e+00	717.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.92	5.00e-139	486.00
IUUC-Ocu-074772	Oryctolagus cuniculus	65.01	0.00e+00	673.00
IUUC-Ola-086964	Oryzias latipes	50.00	4.00e-82	297.00
IUUC-Oga-088188	Otolemur garnettii	65.58	0.00e+00	684.00
IUUC-Oar-090231	Ovis aries	64.07	0.00e+00	701.00
IUUC-Ptr-091434	Pan troglodytes	60.98	0.00e+00	647.00
IUUC-Pan-091868	Papio anubis	63.04	0.00e+00	681.00
IUUC-Psi-093652	Pelodiscus sinensis	63.51	2.00e-162	565.00
IUUC-Pfo-096960	Poecilia formosa	40.03	6.00e-94	338.00
IUUC-Pab-097776	Pongo abelii	64.91	0.00e+00	639.00
IUUC-Pca-100220	Procavia capensis	48.64	5.00e-124	437.00
IUUC-Pva-103135	Pteropus vampyrus	65.75	0.00e+00	654.00
IUUC-Rno-105529	Rattus norvegicus	63.75	0.00e+00	753.00
IUUC-Sar-113109	Sorex araneus	58.25	3.00e-114	405.00
IUUC-Ssc-115271	Sus scrofa	65.97	0.00e+00	703.00
IUUC-Ttr-128267	Tursiops truncatus	63.86	0.00e+00	644.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence