iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033525

UUCD1 version

UUC-EqC-00623

Ensembl Protein ID

ENSECAP00000016789.1

UniProt Accession

F7A2I9; F7A2I9_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018938.1	ENSECAT00000020456.1	ENSECAP00000016789.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-18	67.4	213	280
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.10e-07	28.4	312	338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 213  CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 280
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 312  PSNCLGIRAFADAQGCIELMKVAHSYT 338
           89***********************95 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSGSGRKDFD VKHILRLRWK LFSHPSPSPG GPAGGGCLQQ DGSGSFEHWG PSQSRLLKSQ 60
EKGSMSAFWK KPSSSSSSSS SSPSCSSSSF NPLNGTLLPV STRLQQGAPG QRTQQPARTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGTGGGCT CCCCAACGCA GGTCCTGCGG ACCTGGCCGC GGCTGAGCCT CACGGCTCTG 60
CCGTCCGCGC TTCGGTCGTC GCCTGGCAGG GCGCGCAGCC TGCCTAGCCC CGTCTGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001478	Ailuropoda melanoleuca	97.20	0.00e+00	1362.00
IUUC-Apl-003408	Anas platyrhynchos	96.92	0.00e+00	1119.00
IUUC-Aca-004384	Anolis carolinensis	86.68	0.00e+00	1248.00
IUUC-Bta-012684	Bos taurus	99.14	0.00e+00	1140.00
IUUC-Cja-019103	Callithrix jacchus	96.66	0.00e+00	1351.00
IUUC-Cfa-020670	Canis familiaris	98.54	0.00e+00	1200.00
IUUC-Cpo-021951	Cavia porcellus	98.97	0.00e+00	1144.00
IUUC-Csa-023607	Chlorocebus sabaeus	98.63	0.00e+00	1137.00
IUUC-Cho-024648	Choloepus hoffmanni	87.67	0.00e+00	1139.00
IUUC-Dno-029854	Dasypus novemcinctus	96.26	0.00e+00	1320.00
IUUC-Dor-030497	Dipodomys ordii	79.35	0.00e+00	984.00
IUUC-Fca-035490	Felis catus	99.49	0.00e+00	1140.00
IUUC-Fal-037099	Ficedula albicollis	97.86	0.00e+00	1110.00
IUUC-Gga-041081	Gallus gallus	87.18	0.00e+00	1206.00
IUUC-Gma-043533	Glycine max	32.64	9.00e-39	155.00
IUUC-Ggo-044717	Gorilla gorilla	97.06	0.00e+00	1350.00
IUUC-Hsa-045726	Homo sapiens	97.06	0.00e+00	1350.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	97.33	0.00e+00	1355.00
IUUC-Loc-052321	Lepisosteus oculatus	76.80	0.00e+00	1087.00
IUUC-Laf-054378	Loxodonta africana	96.40	0.00e+00	1342.00
IUUC-Mcc-054985	Macaca mulatta	96.53	0.00e+00	1345.00
IUUC-Mmr-061255	Microcebus murinus	87.20	0.00e+00	1182.00
IUUC-Mdo-062369	Monodelphis domestica	94.26	0.00e+00	1343.00
IUUC-Mmu-063334	Mus musculus	94.94	0.00e+00	1330.00
IUUC-Nle-069856	Nomascus leucogenys	97.20	0.00e+00	1351.00
IUUC-Ocu-074469	Oryctolagus cuniculus	96.80	0.00e+00	1342.00
IUUC-Oin-080100	Oryza indica	29.51	2.00e-34	140.00
IUUC-Opu-083716	Oryza punctata	31.02	2.00e-32	134.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.36	7.00e-33	133.00
IUUC-Oga-088528	Otolemur garnettii	97.89	0.00e+00	1192.00
IUUC-Oar-089603	Ovis aries	98.97	0.00e+00	1137.00
IUUC-Ptr-090657	Pan troglodytes	96.80	0.00e+00	1347.00
IUUC-Psi-092962	Pelodiscus sinensis	96.91	0.00e+00	1122.00
IUUC-Pab-097812	Pongo abelii	96.40	0.00e+00	1319.00
IUUC-Pva-103042	Pteropus vampyrus	96.72	0.00e+00	1344.00
IUUC-Sbi-114612	Sorghum bicolor	28.81	9.00e-35	141.00
IUUC-Ssc-115880	Sus scrofa	99.66	0.00e+00	1145.00
IUUC-Tgu-116624	Taeniopygia guttata	94.98	0.00e+00	984.00
IUUC-Tsy-119339	Tarsius syrichta	89.45	0.00e+00	1211.00
IUUC-Tbe-127398	Tupaia belangeri	100.00	0.00e+00	682.00
IUUC-Ttr-129024	Tursiops truncatus	96.53	0.00e+00	1386.00
IUUC-Vpa-130515	Vicugna pacos	99.48	0.00e+00	1143.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence