iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000038022.11	ENSMUST00000204842.2	ENSMUSP00000145151.1
ENSMUSG00000038022.11	ENSMUST00000053094.7	ENSMUSP00000061221.7

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	RAID2
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/MIU	73.79	0.00e+00	1045.00	IUUC-Hsa-136748
DUB/MINDY	73.79	0.00e+00	1045.00	IUUC-Hsa-136748

Active Site

Position(s)	Description	Evidence
443	Nucleophile	{ECO:0000250\|UniProtKB:Q8N5J2}
664	Proton acceptor	{ECO:0000250\|UniProtKB:Q8N5J2}

Organism

Mus musculus

Functional Description
(View)

Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

Protein Sequence
(Fasta)

MDSLYVEEVA ASLVREFLSR KGLNKTFVTM DQERPRCELS INSRNDLRKV LHLEFLYKEN 60
KAKEKPLRTN LELITRYFLD NVGNTDNSES QEVPIPAIPV PKKNNKLPLR HSETTLVNIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAGGAGT TCTTCCTGGC GCGGATGCCA CCGTCGCCAC GGCAACGCCG CTTTACTGGG 60
CCCAACGGAT TAAGGGGCCT GGGGCTGCAG GCGGCCGCGT GGCCTCGTGG GCAGCGCTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR025257--DUF4205

Pfam

PF13898--DUF4205

SMART

SM01174--DUF4205

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity

KEGG

mmu:330323

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-136380	Ailuropoda melanoleuca	72.77	0.00e+00	1079.00
IUUC-Apl-136386	Anas platyrhynchos	53.66	6.00e-175	607.00
IUUC-Aca-136390	Anolis carolinensis	69.67	7.00e-147	514.00
IUUC-Ame-136408	Astyanax mexicanus	46.15	2.00e-129	456.00
IUUC-Bta-136412	Bos taurus	72.12	0.00e+00	963.00
IUUC-Cja-136425	Callithrix jacchus	66.04	0.00e+00	691.00
IUUC-Cfa-136429	Canis familiaris	71.73	0.00e+00	1052.00
IUUC-Cpo-136433	Cavia porcellus	72.32	0.00e+00	1028.00
IUUC-Cre-136436	Chlamydomonas reinhardtii	46.15	3.00e-43	167.00
IUUC-Csa-136439	Chlorocebus sabaeus	74.05	0.00e+00	1031.00
IUUC-Cho-136443	Choloepus hoffmanni	35.92	7.00e-47	181.00
IUUC-Dre-136453	Danio rerio	48.81	5.00e-135	474.00
IUUC-Dno-136457	Dasypus novemcinctus	83.42	0.00e+00	650.00
IUUC-Dor-136462	Dipodomys ordii	71.31	0.00e+00	1009.00
IUUC-Dme-136465	Drosophila melanogaster	31.00	3.00e-30	126.00
IUUC-Ete-136468	Echinops telfairi	58.45	5.00e-81	295.00
IUUC-Eca-136472	Equus caballus	73.88	0.00e+00	1038.00
IUUC-Fca-136478	Felis catus	72.58	0.00e+00	992.00
IUUC-Fal-136482	Ficedula albicollis	49.32	0.00e+00	656.00
IUUC-Gmo-136487	Gadus morhua	55.59	7.00e-108	384.00
IUUC-Gga-136492	Gallus gallus	55.54	2.00e-172	599.00
IUUC-Gac-136496	Gasterosteus aculeatus	59.50	3.00e-126	446.00
IUUC-Gma-136501	Glycine max	33.13	1.00e-40	160.00
IUUC-Ggo-136503	Gorilla gorilla	73.95	0.00e+00	1029.00
IUUC-Hsa-136748	Homo sapiens	73.79	0.00e+00	1073.00
IUUC-Itr-136511	Ictidomys tridecemlineatus	90.57	1.00e-85	307.00
IUUC-Lch-136514	Latimeria chalumnae	75.88	7.00e-92	329.00
IUUC-Loc-136522	Lepisosteus oculatus	48.45	0.00e+00	654.00
IUUC-Laf-136526	Loxodonta africana	35.01	2.00e-54	206.00
IUUC-Mcc-136531	Macaca mulatta	74.31	0.00e+00	1026.00
IUUC-Meu-136535	Macropus eugenii	69.21	7.00e-138	484.00
IUUC-Mtr-136540	Medicago truncatula	33.84	3.00e-42	166.00
IUUC-Mla-136541	Melampsora laricipopulina	38.71	5.80e-02	31.20
IUUC-Mga-136544	Meleagris gallopavo	51.45	0.00e+00	627.00
IUUC-Mmr-136548	Microcebus murinus	74.48	0.00e+00	1081.00
IUUC-Mdo-136552	Monodelphis domestica	53.07	0.00e+00	693.00
IUUC-Mac-136559	Musa acuminata	33.33	1.00e-38	154.00
IUUC-Mpu-136562	Mustela putorius furo	72.38	0.00e+00	1036.00
IUUC-Mlu-136566	Myotis lucifugus	68.88	0.00e+00	933.00
IUUC-Nle-136573	Nomascus leucogenys	73.27	0.00e+00	1038.00
IUUC-Opr-136577	Ochotona princeps	64.10	0.00e+00	691.00
IUUC-Ont-136580	Oreochromis niloticus	59.83	1.00e-126	447.00
IUUC-Oan-136583	Ornithorhynchus anatinus	65.99	1.00e-149	522.00
IUUC-Ocu-136586	Oryctolagus cuniculus	71.24	0.00e+00	1012.00
IUUC-Oga-136615	Otolemur garnettii	73.46	0.00e+00	1065.00
IUUC-Oar-136620	Ovis aries	35.56	5.00e-56	211.00
IUUC-Ptr-136624	Pan troglodytes	73.79	0.00e+00	1060.00
IUUC-Pan-136628	Papio anubis	74.44	0.00e+00	1030.00
IUUC-Psi-136632	Pelodiscus sinensis	64.34	8.00e-168	583.00
IUUC-Ppa-136638	Physcomitrella patens	36.39	1.00e-42	167.00
IUUC-Pfo-136642	Poecilia formosa	39.64	1.00e-138	486.00
IUUC-Pab-136646	Pongo abelii	73.66	0.00e+00	1050.00
IUUC-Pca-136653	Procavia capensis	59.75	6.00e-139	488.00
IUUC-Pva-136660	Pteropus vampyrus	68.76	0.00e+00	963.00
IUUC-Rno-136666	Rattus norvegicus	91.14	0.00e+00	1269.00
IUUC-Sha-136672	Sarcophilus harrisii	47.29	2.00e-120	426.00
IUUC-Sar-136686	Sorex araneus	57.10	0.00e+00	786.00
IUUC-Ssc-136692	Sus scrofa	56.80	0.00e+00	643.00
IUUC-Tgu-136695	Taeniopygia guttata	69.74	3.00e-163	568.00
IUUC-Tru-136699	Takifugu rubripes	59.55	2.00e-127	449.00
IUUC-Tsy-136702	Tarsius syrichta	54.82	8.00e-175	607.00
IUUC-Tni-136707	Tetraodon nigroviridis	50.79	2.00e-114	406.00
IUUC-Tbe-136720	Tupaia belangeri	66.56	2.00e-120	426.00
IUUC-Ttr-136723	Tursiops truncatus	68.34	0.00e+00	889.00
IUUC-Vpa-136730	Vicugna pacos	59.73	4.00e-112	399.00
IUUC-Xtr-136735	Xenopus tropicalis	47.27	1.00e-165	576.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence