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Tag Content
iUUCD ID IUUC-Cja-019138
Ensembl Protein ID ENSCJAP00000018765.2
UniProt Accession F7EBF4; F7EBF4_CALJA
Genbank Protein ID ENSCJAP00000018765
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID ACFV01135672
Gene Name KMT2B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000010126.3 ENSCJAT00000019666.2 ENSCJAP00000018617.2
ENSCJAG00000010126.3 ENSCJAT00000019796.2 ENSCJAP00000018740.2
ENSCJAG00000010126.3 ENSCJAT00000019821.2 ENSCJAP00000018765.2
ENSCJAG00000010126.3 ENSCJAT00000019671.2 ENSCJAP00000018622.2
ENSCJAG00000010126.3 ENSCJAT00000019847.3 ENSCJAP00000018789.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.10e-29 103.3 1119 1172
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1119 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1172
           58********************************.88888877777******876 PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
FTQASDGDAL PSPHRASGSR GPRPRHPGSG SPRGRRGNGA ERVRVALRRG GGATGPGGAE 60
PGEDTALLRL LGLRRGLRRL RRLWAGPRVQ LEEESSDGES DEEEFQGFHS DEDVAPSSLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-019138|E3,PHD|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGACTCCCC TGGCACCTGA GGTCTCCCAC GCTCCACCTG CGCGCCCACC GCTCCCTCCG 60
CCGCCCCTTC CCCAGCCCTA CCCCGCAGAC TCCCCCTGCC TCCCAGATTT CCAATAAAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-019138|E3,PHD|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002367 Ailuropoda melanoleuca 94.80 0.00e+00 3031.00
IUUC-Aca-004718 Anolis carolinensis 57.26 0.00e+00 1476.00
IUUC-Ame-011927 Astyanax mexicanus 43.30 0.00e+00 848.00
IUUC-Bta-013578 Bos taurus 93.49 0.00e+00 2915.00
IUUC-Bdi-014882 Brachypodium distachyon 33.50 2.00e-27 117.00
IUUC-Bra-017422 Brassica rapa 32.07 4.00e-28 119.00
IUUC-Cfa-020020 Canis familiaris 91.12 0.00e+00 3136.00
IUUC-Cpo-021552 Cavia porcellus 88.27 0.00e+00 3335.00
IUUC-Csa-024216 Chlorocebus sabaeus 94.64 0.00e+00 3361.00
IUUC-Dre-027440 Danio rerio 44.90 0.00e+00 905.00
IUUC-Dno-029583 Dasypus novemcinctus 94.04 0.00e+00 3028.00
IUUC-Dor-030903 Dipodomys ordii 86.30 0.00e+00 2136.00
IUUC-Dme-032023 Drosophila melanogaster 47.43 3.00e-93 338.00
IUUC-Eca-034026 Equus caballus 94.21 0.00e+00 1954.00
IUUC-Eeu-034687 Erinaceus europaeus 93.01 0.00e+00 1121.00
IUUC-Fca-036311 Felis catus 90.38 0.00e+00 3216.00
IUUC-Gmo-039265 Gadus morhua 44.77 0.00e+00 810.00
IUUC-Gac-042202 Gasterosteus aculeatus 47.77 0.00e+00 738.00
IUUC-Ggo-044791 Gorilla gorilla 96.87 0.00e+00 2210.00
IUUC-Hsa-046988 Homo sapiens 94.73 0.00e+00 3273.00
IUUC-Hvu-047762 Hordeum vulgare 36.57 4.00e-20 92.80
IUUC-Itr-048907 Ictidomys tridecemlineatus 88.90 0.00e+00 3304.00
IUUC-Lpe-051476 Leersia perrieri 31.51 4.00e-24 107.00
IUUC-Loc-052252 Lepisosteus oculatus 53.59 0.00e+00 778.00
IUUC-Laf-053703 Loxodonta africana 92.75 0.00e+00 2189.00
IUUC-Mcc-054782 Macaca mulatta 92.76 0.00e+00 2556.00
IUUC-Meu-056046 Macropus eugenii 78.59 0.00e+00 1868.00
IUUC-Mmr-061316 Microcebus murinus 91.45 0.00e+00 2837.00
IUUC-Mdo-062648 Monodelphis domestica 81.24 0.00e+00 2745.00
IUUC-Mmu-063579 Mus musculus 87.42 0.00e+00 3193.00
IUUC-Mac-064935 Musa acuminata 32.41 2.00e-30 127.00
IUUC-Mpu-066710 Mustela putorius furo 91.39 0.00e+00 3201.00
IUUC-Mlu-067559 Myotis lucifugus 88.63 0.00e+00 2425.00
IUUC-Nle-070085 Nomascus leucogenys 92.26 0.00e+00 2241.00
IUUC-Opr-071148 Ochotona princeps 87.08 0.00e+00 3180.00
IUUC-Ont-071626 Oreochromis niloticus 48.48 0.00e+00 782.00
IUUC-Ocu-074475 Oryctolagus cuniculus 89.81 0.00e+00 3281.00
IUUC-Obr-076458 Oryza brachyantha 34.48 4.00e-28 119.00
IUUC-Ogl-077851 Oryza glaberrima 36.26 4.00e-28 119.00
IUUC-Ogu-078706 Oryza glumaepatula 36.26 2.00e-28 121.00
IUUC-Oin-079802 Oryza indica 31.43 3.00e-23 103.00
IUUC-Osa-085421 Oryza sativa 36.26 5.00e-28 119.00
IUUC-Ola-086609 Oryzias latipes 51.19 0.00e+00 753.00
IUUC-Oga-088140 Otolemur garnettii 91.42 0.00e+00 3210.00
IUUC-Oar-089447 Ovis aries 92.31 0.00e+00 2028.00
IUUC-Ptr-090902 Pan troglodytes 94.64 0.00e+00 3297.00
IUUC-Pan-091930 Papio anubis 94.64 0.00e+00 3364.00
IUUC-Ppa-095221 Physcomitrella patens 36.54 8.00e-31 128.00
IUUC-Pfo-096884 Poecilia formosa 45.09 0.00e+00 875.00
IUUC-Pab-098404 Pongo abelii 97.29 0.00e+00 1894.00
IUUC-Pop-099585 Populus trichocarpa 33.50 3.00e-27 117.00
IUUC-Pca-100949 Procavia capensis 82.53 0.00e+00 1244.00
IUUC-Ppe-101920 Prunus persica 32.29 5.00e-28 119.00
IUUC-Pva-102634 Pteropus vampyrus 90.52 0.00e+00 3241.00
IUUC-Rno-105870 Rattus norvegicus 87.06 0.00e+00 3250.00
IUUC-Sit-110552 Setaria italica 34.33 7.00e-29 122.00
IUUC-Sar-113289 Sorex araneus 89.59 0.00e+00 1781.00
IUUC-Ssc-115509 Sus scrofa 91.03 0.00e+00 3212.00
IUUC-Tru-118413 Takifugu rubripes 52.31 0.00e+00 784.00
IUUC-Tca-121624 Theobroma cacao 32.11 6.00e-28 119.00
IUUC-Tae-125629 Triticum aestivum 36.57 3.00e-20 93.20
IUUC-Tbe-127825 Tupaia belangeri 84.19 0.00e+00 1420.00
IUUC-Ttr-128754 Tursiops truncatus 94.11 0.00e+00 1228.00
IUUC-Xtr-132838 Xenopus tropicalis 48.70 0.00e+00 993.00
IUUC-Xma-133119 Xiphophorus maculatus 42.82 0.00e+00 972.00
Created Date 25-Jun-2017

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