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Tag Content
UUCD2 ID IUUC-Xtr-132972
UUCD1 version UUC-XeT-00837
Ensembl Protein ID ENSXETP00000016718.2
UniProt Accession F7EP40; ZNRF1_XENTR
Genbank Protein ID ENSXETP00000016718
Protein Name E3 ubiquitin-protein ligase ZNRF1; RING-type E3 ubiquitin transferase ZNRF1; Zinc/RING finger protein 1
Genbank Nucleotide ID AAMC01003501
Gene Name znrf1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000007681.2 ENSXETT00000016718.2 ENSXETP00000016718.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 63.88 3.00e-61 231.00 IUUC-Hsa-046894
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase that plays a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity.
 E3 ubiquitin-protein ligase that plays a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity.
Protein Sequence
(Fasta)
MGGKQSSASR SRAPFPGVSS DDSAVPPSSN FGHFRAGGAM GLRSRSVSSV SGLDPPAPGL 60
PFGLYRAGPD TERGGSSGSE DSRGDLYLGS RASLADTLQI APRWIGAHSG FRCPICSKSV 120
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Protein Fasta Sequence


>IUUC-Xtr-132972|E3,RING|Xenopus tropicalis
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Nucleotide Sequence
(Fasta)
TCTCTATCCA CCAAACGCGC ACACAGTGCC TAATTCTAGC GCTGTGTGCC CCATGGGGGG 60
GAAGCAGAGC TCAGCCTCCC GCTCTCGGGC TCCCTTCCCG GGGGTTTCCT CGGATGACAG 120
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Nucleotide Fasta Sequence


>IUUC-Xtr-132972|E3,RING|Xenopus tropicalis
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0449--Lipoprotein
KW-0458--Lysosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
Gene Ontology

GO:0005768--C:endosome
GO:0005764--C:lysosome
GO:0016020--C:membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
KEGG xtr:549731
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002006 Ailuropoda melanoleuca 70.10 9.00e-40 154.00
IUUC-Apl-004093 Anas platyrhynchos 89.09 2.00e-53 200.00
IUUC-Aca-004497 Anolis carolinensis 70.10 6.00e-41 160.00
IUUC-Acl-008261 Aspergillus clavatus 50.00 5.00e-09 55.80
IUUC-Afl-008724 Aspergillus flavus 52.27 1.00e-09 57.80
IUUC-Afu-008835 Aspergillus fumigatus 46.15 1.00e-08 55.10
IUUC-Ang-009666 Aspergillus niger 46.30 4.00e-10 59.30
IUUC-Ate-010331 Aspergillus terreus 50.00 7.00e-09 55.10
IUUC-Ame-011041 Astyanax mexicanus 69.07 3.00e-41 160.00
IUUC-Bgr-012049 Blumeria graminis 45.95 1.00e-06 47.80
IUUC-Bta-012934 Bos taurus 70.04 6.00e-74 270.00
IUUC-Cel-018347 Caenorhabditis elegans 60.00 3.00e-31 127.00
IUUC-Cja-019419 Callithrix jacchus 69.60 6.00e-74 270.00
IUUC-Cfa-020388 Canis familiaris 69.41 2.00e-59 221.00
IUUC-Cpo-021584 Cavia porcellus 70.04 2.00e-74 271.00
IUUC-Csa-023094 Chlorocebus sabaeus 70.10 4.00e-40 157.00
IUUC-Cin-025162 Ciona intestinalis 44.03 2.00e-31 128.00
IUUC-Csv-026373 Ciona savignyi 45.52 5.00e-32 130.00
IUUC-Cgl-026728 Colletotrichum gloeosporioides 54.00 6.00e-09 55.50
IUUC-Dre-027713 Danio rerio 67.91 7.00e-73 266.00
IUUC-Dno-029420 Dasypus novemcinctus 70.10 4.00e-40 157.00
IUUC-Dse-031322 Dothistroma septosporum 44.68 3.00e-08 53.50
IUUC-Dme-031584 Drosophila melanogaster 69.15 1.00e-37 149.00
IUUC-Eca-033414 Equus caballus 88.39 8.00e-56 207.00
IUUC-Fca-036570 Felis catus 70.48 8.00e-75 272.00
IUUC-Fal-037096 Ficedula albicollis 77.44 5.00e-55 206.00
IUUC-Fox-038020 Fusarium oxysporum 63.89 1.00e-09 58.20
IUUC-Fso-038176 Fusarium solani 51.02 2.00e-08 54.30
IUUC-Gmo-039148 Gadus morhua 64.95 6.00e-39 153.00
IUUC-Ggr-039766 Gaeumannomyces graminis 46.77 1.00e-08 54.70
IUUC-Gga-041242 Gallus gallus 62.67 5.00e-64 236.00
IUUC-Gac-041711 Gasterosteus aculeatus 68.04 5.00e-39 153.00
IUUC-Hsa-046894 Homo sapiens 70.04 2.00e-74 271.00
IUUC-Itr-048339 Ictidomys tridecemlineatus 92.94 6.00e-45 171.00
IUUC-Lch-049870 Latimeria chalumnae 65.38 5.00e-29 120.00
IUUC-Loc-052268 Lepisosteus oculatus 67.74 1.00e-72 265.00
IUUC-Lma-053072 Leptosphaeria maculans 42.59 1.00e-07 51.60
IUUC-Laf-054263 Loxodonta africana 70.04 3.00e-74 270.00
IUUC-Mcc-055078 Macaca mulatta 70.10 4.00e-40 157.00
IUUC-Mpo-057355 Magnaporthe poae 46.77 1.00e-08 54.70
IUUC-Mga-059226 Meleagris gallopavo 94.12 3.00e-45 172.00
IUUC-Mmr-061658 Microcebus murinus 76.74 1.00e-39 153.00
IUUC-Mdo-062052 Monodelphis domestica 57.04 5.00e-40 157.00
IUUC-Mmu-064275 Mus musculus 69.60 1.00e-73 269.00
IUUC-Mpu-066334 Mustela putorius furo 70.48 8.00e-75 272.00
IUUC-Mlu-067491 Myotis lucifugus 68.86 9.00e-74 269.00
IUUC-Nfi-068593 Neosartorya fischeri 46.15 6.00e-09 55.50
IUUC-Ncr-068662 Neurospora crassa 48.98 1.00e-08 54.70
IUUC-Nle-069306 Nomascus leucogenys 70.10 6.00e-39 153.00
IUUC-Ont-071907 Oreochromis niloticus 65.90 7.00e-70 256.00
IUUC-Oan-072941 Ornithorhynchus anatinus 85.19 4.00e-36 141.00
IUUC-Ocu-074256 Oryctolagus cuniculus 68.28 1.00e-72 265.00
IUUC-Ola-087551 Oryzias latipes 89.66 4.00e-45 171.00
IUUC-Oga-088009 Otolemur garnettii 70.10 3.00e-40 157.00
IUUC-Ptr-091609 Pan troglodytes 69.07 6.00e-40 157.00
IUUC-Pan-092598 Papio anubis 70.10 4.00e-40 157.00
IUUC-Psi-093749 Pelodiscus sinensis 75.29 5.00e-39 151.00
IUUC-Pma-094361 Petromyzon marinus 72.41 5.00e-37 144.00
IUUC-Pfo-097234 Poecilia formosa 66.97 4.00e-72 263.00
IUUC-Pab-098719 Pongo abelii 70.04 2.00e-74 271.00
IUUC-Pva-102216 Pteropus vampyrus 76.47 5.00e-39 154.00
IUUC-Pte-104063 Pyrenophora teres 46.67 2.00e-07 50.80
IUUC-Pyt-104423 Pyrenophora triticirepentis 46.67 1.00e-07 50.80
IUUC-Rno-105985 Rattus norvegicus 69.16 2.00e-73 268.00
IUUC-Sja-107832 Schizosaccharomyces japonicus 31.48 3.00e-08 52.00
IUUC-Ssl-108602 Sclerotinia sclerotiorum 48.00 2.00e-07 50.80
IUUC-Ssc-116023 Sus scrofa 76.74 2.00e-39 152.00
IUUC-Tgu-116682 Taeniopygia guttata 82.79 3.00e-56 210.00
IUUC-Tru-117571 Takifugu rubripes 54.86 2.00e-41 161.00
IUUC-Tni-120337 Tetraodon nigroviridis 63.92 1.00e-37 149.00
IUUC-Tre-122233 Trichoderma reesei 55.88 4.00e-06 46.60
IUUC-Tvi-122664 Trichoderma virens 54.00 1.00e-08 55.10
IUUC-Tme-127002 Tuber melanosporum 58.33 3.00e-10 60.10
IUUC-Tbe-127983 Tupaia belangeri 70.10 1.00e-39 155.00
IUUC-Ttr-129090 Tursiops truncatus 70.10 3.00e-40 157.00
IUUC-Vda-129847 Verticillium dahliae 54.00 3.00e-09 56.60
IUUC-Xma-134213 Xiphophorus maculatus 66.82 4.00e-71 260.00
IUUC-Yli-134502 Yarrowia lipolytica 36.36 2.00e-11 62.80
Created Date 25-Jun-2017

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