iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059937

UUCD1 version

UUC-MeG-00043

Ensembl Protein ID

ENSMGAP00000000355.1

UniProt Accession

G1MQJ7; G1MQJ7_MELGA

Protein Name

Uncharacterized protein

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000000962.1	ENSMGAT00000000991.1	ENSMGAP00000000355.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.90e-09	35.8	275	313
UBD/Alpha-Helix/CUE	4.00e-12	45.6	390	431

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 275  CAICWDSMQS-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 313
           ********99.9*****************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y v+ ++L ++t s+e +++n+Leg 
   Q: 390  QLNAMAHQIQEMFPQVPYHVVLQDL-QLTRSVEITTDNILEGR 431
           5889*********************.***************95 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

PSLPERGGRS VADRFVSVQV LVNTACCVLM LVAKLIQRVV FGPLRVSERQ HLKDKFWNFI 60
FYKFIFIFGV LNVQTVEEVV MWCLWFSGLV FLHLMVQLCK DRFEYLSFSP TTPMSSHVRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTCCCTCC CGGAGCGGGG CGGGAGATCC GTCGCTGACC GCTTCGTTTC CGTGCAGGTG 60
CTGGTGAACA CGGCCTGCTG TGTCCTGATG CTGGTCGCTA AGCTGATCCA GCGCGTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	26.52	3.00e-25	109.00
IUUC-Aml-001300	Ailuropoda melanoleuca	87.34	0.00e+00	951.00
IUUC-Atr-002892	Amborella trichopoda	29.36	1.00e-34	140.00
IUUC-Apl-003404	Anas platyrhynchos	94.62	0.00e+00	993.00
IUUC-Aca-004559	Anolis carolinensis	87.57	0.00e+00	889.00
IUUC-Aly-005440	Arabidopsis lyrata	30.10	2.00e-32	132.00
IUUC-Ath-006702	Arabidopsis thaliana	33.10	2.00e-36	145.00
IUUC-Ame-011640	Astyanax mexicanus	75.90	0.00e+00	768.00
IUUC-Bta-012980	Bos taurus	87.90	0.00e+00	958.00
IUUC-Bdi-015070	Brachypodium distachyon	29.49	8.00e-37	147.00
IUUC-Bol-015593	Brassica oleracea	32.28	4.00e-36	145.00
IUUC-Bra-017516	Brassica rapa	34.15	1.00e-36	147.00
IUUC-Cel-018598	Caenorhabditis elegans	23.93	1.00e-29	124.00
IUUC-Cja-019577	Callithrix jacchus	86.47	0.00e+00	969.00
IUUC-Cfa-020793	Canis familiaris	87.86	0.00e+00	940.00
IUUC-Cpo-022387	Cavia porcellus	86.28	0.00e+00	951.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	24.44	4.00e-26	111.00
IUUC-Csa-023168	Chlorocebus sabaeus	86.37	0.00e+00	968.00
IUUC-Cho-024433	Choloepus hoffmanni	90.31	0.00e+00	782.00
IUUC-Cin-025215	Ciona intestinalis	49.07	2.00e-142	499.00
IUUC-Csv-026133	Ciona savignyi	48.21	5.00e-131	461.00
IUUC-Cne-027002	Cryptococcus neoformans	27.46	1.00e-26	114.00
IUUC-Cme-027285	Cyanidioschyzon merolae	29.66	4.00e-23	102.00
IUUC-Dre-027594	Danio rerio	75.64	0.00e+00	722.00
IUUC-Dno-029407	Dasypus novemcinctus	88.81	0.00e+00	935.00
IUUC-Dor-030961	Dipodomys ordii	88.89	0.00e+00	956.00
IUUC-Ete-032962	Echinops telfairi	81.00	0.00e+00	790.00
IUUC-Eca-033683	Equus caballus	86.94	0.00e+00	916.00
IUUC-Eeu-034515	Erinaceus europaeus	94.81	9.00e-77	280.00
IUUC-Fca-035398	Felis catus	90.62	0.00e+00	918.00
IUUC-Fal-036758	Ficedula albicollis	86.02	0.00e+00	920.00
IUUC-Gmo-039014	Gadus morhua	74.02	0.00e+00	721.00
IUUC-Gga-040575	Gallus gallus	98.57	0.00e+00	1063.00
IUUC-Gac-041414	Gasterosteus aculeatus	71.46	0.00e+00	693.00
IUUC-Gma-044123	Glycine max	27.63	4.00e-33	135.00
IUUC-Hsa-046272	Homo sapiens	88.93	0.00e+00	968.00
IUUC-Hvu-047279	Hordeum vulgare	30.74	2.00e-37	149.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	88.61	0.00e+00	954.00
IUUC-Lch-050491	Latimeria chalumnae	79.66	0.00e+00	816.00
IUUC-Loc-052758	Lepisosteus oculatus	80.27	0.00e+00	784.00
IUUC-Laf-053452	Loxodonta africana	88.93	0.00e+00	966.00
IUUC-Mcc-055820	Macaca mulatta	88.87	0.00e+00	943.00
IUUC-Meu-056726	Macropus eugenii	85.04	0.00e+00	741.00
IUUC-Mtr-058639	Medicago truncatula	28.21	2.00e-34	140.00
IUUC-Mla-059168	Melampsora laricipopulina	26.01	6.00e-26	112.00
IUUC-Mvi-060515	Microbotryum violaceum	25.74	2.00e-23	103.00
IUUC-Mmr-060730	Microcebus murinus	86.75	0.00e+00	952.00
IUUC-Mdo-062771	Monodelphis domestica	87.73	0.00e+00	955.00
IUUC-Mmu-064219	Mus musculus	87.00	0.00e+00	958.00
IUUC-Mac-064789	Musa acuminata	28.79	6.00e-35	141.00
IUUC-Mpu-066796	Mustela putorius furo	88.14	0.00e+00	935.00
IUUC-Mlu-068189	Myotis lucifugus	86.79	0.00e+00	904.00
IUUC-Nle-069239	Nomascus leucogenys	86.47	0.00e+00	969.00
IUUC-Opr-070702	Ochotona princeps	79.35	6.00e-123	434.00
IUUC-Ont-072033	Oreochromis niloticus	74.07	0.00e+00	752.00
IUUC-Oan-073717	Ornithorhynchus anatinus	83.72	0.00e+00	849.00
IUUC-Ocu-074145	Oryctolagus cuniculus	87.46	0.00e+00	966.00
IUUC-Oba-075221	Oryza barthii	28.52	1.00e-34	140.00
IUUC-Obr-076914	Oryza brachyantha	29.77	1.00e-36	147.00
IUUC-Ogl-077929	Oryza glaberrima	51.16	1.00e-11	62.00
IUUC-Ogu-078124	Oryza glumaepatula	28.52	1.00e-34	140.00
IUUC-Oin-080013	Oryza indica	28.38	2.00e-33	136.00
IUUC-Olo-080247	Oryza longistaminata	28.85	6.00e-31	128.00
IUUC-Ome-081769	Oryza meridionalis	29.39	3.00e-36	145.00
IUUC-Oni-082946	Oryza nivara	28.52	1.00e-34	140.00
IUUC-Opu-083268	Oryza punctata	27.76	1.00e-23	104.00
IUUC-Oru-085114	Oryza rufipogon	28.52	1.00e-34	140.00
IUUC-Osa-085829	Oryza sativa	29.05	1.00e-35	144.00
IUUC-Ola-087152	Oryzias latipes	73.00	0.00e+00	735.00
IUUC-Olu-087894	Ostreococcus lucimarinus	27.06	3.00e-27	115.00
IUUC-Oga-088486	Otolemur garnettii	89.27	0.00e+00	957.00
IUUC-Oar-089310	Ovis aries	87.86	0.00e+00	957.00
IUUC-Ptr-090649	Pan troglodytes	89.07	0.00e+00	967.00
IUUC-Pan-091692	Papio anubis	84.29	0.00e+00	902.00
IUUC-Psi-093064	Pelodiscus sinensis	96.98	0.00e+00	793.00
IUUC-Pma-094763	Petromyzon marinus	78.28	5.00e-98	349.00
IUUC-Ppa-095969	Physcomitrella patens	29.88	3.00e-38	152.00
IUUC-Pfo-096810	Poecilia formosa	72.68	0.00e+00	737.00
IUUC-Pab-097859	Pongo abelii	89.05	0.00e+00	946.00
IUUC-Pop-099576	Populus trichocarpa	26.76	1.00e-28	121.00
IUUC-Pca-100344	Procavia capensis	86.28	0.00e+00	924.00
IUUC-Ppe-101829	Prunus persica	28.33	1.00e-36	147.00
IUUC-Pva-103114	Pteropus vampyrus	61.07	3.00e-158	551.00
IUUC-Pgr-103286	Puccinia graminis	24.39	2.00e-22	100.00
IUUC-Ptt-103919	Puccinia triticina	23.87	1.00e-20	94.40
IUUC-Rno-105880	Rattus norvegicus	85.33	0.00e+00	931.00
IUUC-Sha-107015	Sarcophilus harrisii	90.02	0.00e+00	925.00
IUUC-Spo-108308	Schizosaccharomyces pombe	23.80	6.00e-21	95.50
IUUC-Smo-109223	Selaginella moellendorffii	31.21	4.00e-31	128.00
IUUC-Sit-110276	Setaria italica	29.39	2.00e-35	143.00
IUUC-Sly-111819	Solanum lycopersicum	29.86	4.00e-35	142.00
IUUC-Stu-112048	Solanum tuberosum	26.30	6.00e-31	128.00
IUUC-Sar-113397	Sorex araneus	95.42	0.00e+00	744.00
IUUC-Sbi-114192	Sorghum bicolor	29.61	1.00e-36	147.00
IUUC-Sre-115212	Sporisorium reilianum	25.97	4.00e-21	96.30
IUUC-Ssc-115988	Sus scrofa	80.56	2.00e-123	434.00
IUUC-Tgu-116717	Taeniopygia guttata	93.93	0.00e+00	959.00
IUUC-Tru-117805	Takifugu rubripes	73.13	0.00e+00	773.00
IUUC-Tsy-119442	Tarsius syrichta	82.97	0.00e+00	857.00
IUUC-Tni-119777	Tetraodon nigroviridis	70.69	1.00e-176	612.00
IUUC-Tca-121462	Theobroma cacao	28.67	1.00e-34	140.00
IUUC-Tae-124673	Triticum aestivum	29.81	2.00e-38	153.00
IUUC-Tur-126538	Triticum urartu	26.89	3.00e-25	109.00
IUUC-Tme-127197	Tuber melanosporum	28.20	5.00e-21	96.30
IUUC-Tbe-127322	Tupaia belangeri	65.96	6.00e-108	384.00
IUUC-Ttr-128181	Tursiops truncatus	87.63	0.00e+00	952.00
IUUC-Vpa-130483	Vicugna pacos	83.10	0.00e+00	642.00
IUUC-Vvi-130944	Vitis vinifera	28.76	1.00e-33	137.00
IUUC-Xtr-132614	Xenopus tropicalis	79.25	0.00e+00	763.00
IUUC-Xma-133943	Xiphophorus maculatus	72.52	0.00e+00	733.00
IUUC-Yli-134552	Yarrowia lipolytica	22.56	2.00e-11	63.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence