iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067416

Ensembl Protein ID

ENSMLUP00000005728.2

UniProt Accession

G1P6M6; G1P6M6_MYOLU

Genbank Protein ID

ENSMLUP00000005728

Protein Name

Protein kinase C

Genbank Nucleotide ID

AAPE02018150

Gene Name

PRKCI

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006267.2	ENSMLUT00000006273.2	ENSMLUP00000005728.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	95.31	0.00e+00	1118.00	IUUC-Hsa-046991

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

CWVPRRGRGG GGRGRWEEPR GSGCPGEATL GSAPRAGAQG EERRAAAPGR LRQPSPPARP 60
QPPRPPASRR GSQEMPTQRD STTMSHPIAG GGFGDHAHQV RVKAYYRGDI MITHFEPSIS 120

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Nucleotide Sequence
(Fasta)

TGCTGGGTTC CGCGCCGCGG TAGAGGCGGT GGTGGCCGCG GGCGGTGGGA GGAGCCGCGT 60
GGTTCCGGCT GCCCGGGCGA GGCGACCCTT GGGTCCGCGC CGCGGGCAGG AGCGCAGGGA 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR034661--aPKC_iota
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005634--C:nucleus
GO:0043220--C:Schmidt-Lanterman incisure
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0005543--F:phospholipid binding
GO:0004697--F:protein kinase C activity
GO:0007015--P:actin filament organization
GO:0045216--P:cell-cell junction organization
GO:0032869--P:cellular response to insulin stimulus
GO:0035089--P:establishment of apical/basal cell polarity
GO:0042462--P:eye photoreceptor cell development
GO:0035556--P:intracellular signal transduction
GO:0034351--P:negative regulation of glial cell apoptotic process
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0018105--P:peptidyl-serine phosphorylation
GO:2000353--P:positive regulation of endothelial cell apoptotic process
GO:0090004--P:positive regulation of establishment of protein localization to plasma membrane
GO:0060252--P:positive regulation of glial cell proliferation
GO:0046326--P:positive regulation of glucose import
GO:0010976--P:positive regulation of neuron projection development
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	95.80	0.00e+00	987.00
IUUC-Apl-003711	Anas platyrhynchos	92.74	0.00e+00	1028.00
IUUC-Aca-005142	Anolis carolinensis	91.83	0.00e+00	1052.00
IUUC-Ame-010977	Astyanax mexicanus	85.09	0.00e+00	983.00
IUUC-Bta-013414	Bos taurus	91.76	0.00e+00	1160.00
IUUC-Bol-015169	Brassica oleracea	35.29	6.00e-51	196.00
IUUC-Cel-018340	Caenorhabditis elegans	56.29	0.00e+00	668.00
IUUC-Cja-019802	Callithrix jacchus	96.45	0.00e+00	1077.00
IUUC-Cfa-021236	Canis familiaris	94.98	0.00e+00	1115.00
IUUC-Cpo-022127	Cavia porcellus	94.36	0.00e+00	1039.00
IUUC-Csa-023332	Chlorocebus sabaeus	99.17	0.00e+00	944.00
IUUC-Cho-025054	Choloepus hoffmanni	99.19	6.00e-70	258.00
IUUC-Cin-025740	Ciona intestinalis	57.21	0.00e+00	661.00
IUUC-Csv-026145	Ciona savignyi	78.36	2.00e-174	605.00
IUUC-Dre-028444	Danio rerio	86.10	0.00e+00	1002.00
IUUC-Dno-029228	Dasypus novemcinctus	99.68	0.00e+00	643.00
IUUC-Dme-031630	Drosophila melanogaster	79.31	3.00e-171	595.00
IUUC-Ete-032633	Echinops telfairi	73.17	0.00e+00	646.00
IUUC-Eca-033572	Equus caballus	96.09	0.00e+00	1068.00
IUUC-Eeu-035110	Erinaceus europaeus	94.90	0.00e+00	1108.00
IUUC-Fca-035559	Felis catus	95.48	0.00e+00	1134.00
IUUC-Fal-036953	Ficedula albicollis	93.43	0.00e+00	1039.00
IUUC-Gmo-039334	Gadus morhua	84.92	0.00e+00	1001.00
IUUC-Gga-040223	Gallus gallus	91.17	0.00e+00	1068.00
IUUC-Gac-042113	Gasterosteus aculeatus	84.92	0.00e+00	1007.00
IUUC-Ggo-044520	Gorilla gorilla	88.96	0.00e+00	1013.00
IUUC-Hsa-046991	Homo sapiens	95.31	0.00e+00	1135.00
IUUC-Lch-050263	Latimeria chalumnae	85.59	0.00e+00	1020.00
IUUC-Loc-052221	Lepisosteus oculatus	86.10	0.00e+00	1003.00
IUUC-Laf-053591	Loxodonta africana	94.97	0.00e+00	1128.00
IUUC-Mcc-055118	Macaca mulatta	92.63	0.00e+00	1105.00
IUUC-Mga-059886	Meleagris gallopavo	92.57	0.00e+00	1028.00
IUUC-Mmr-060926	Microcebus murinus	95.48	0.00e+00	1134.00
IUUC-Mdo-062698	Monodelphis domestica	90.59	0.00e+00	1060.00
IUUC-Mmu-063689	Mus musculus	94.47	0.00e+00	1114.00
IUUC-Mpu-066630	Mustela putorius furo	95.54	0.00e+00	1103.00
IUUC-Nle-069811	Nomascus leucogenys	95.48	0.00e+00	1134.00
IUUC-Opr-070466	Ochotona princeps	86.35	0.00e+00	738.00
IUUC-Ont-072278	Oreochromis niloticus	83.62	0.00e+00	950.00
IUUC-Oan-073651	Ornithorhynchus anatinus	98.07	0.00e+00	739.00
IUUC-Ocu-074383	Oryctolagus cuniculus	95.14	0.00e+00	1130.00
IUUC-Ola-087283	Oryzias latipes	74.87	0.00e+00	767.00
IUUC-Oga-088337	Otolemur garnettii	86.61	0.00e+00	1011.00
IUUC-Oar-089954	Ovis aries	96.10	0.00e+00	1075.00
IUUC-Ptr-091673	Pan troglodytes	95.31	0.00e+00	1135.00
IUUC-Pan-092494	Papio anubis	89.15	0.00e+00	1155.00
IUUC-Psi-094044	Pelodiscus sinensis	90.62	0.00e+00	1066.00
IUUC-Pfo-096661	Poecilia formosa	83.53	0.00e+00	976.00
IUUC-Pab-097659	Pongo abelii	91.06	0.00e+00	1151.00
IUUC-Pca-101107	Procavia capensis	98.21	0.00e+00	786.00
IUUC-Rno-105790	Rattus norvegicus	94.81	0.00e+00	1121.00
IUUC-Sha-106895	Sarcophilus harrisii	93.83	0.00e+00	1028.00
IUUC-Sar-113513	Sorex araneus	93.46	1.00e-163	570.00
IUUC-Ssc-115835	Sus scrofa	95.41	0.00e+00	978.00
IUUC-Tgu-116874	Taeniopygia guttata	90.86	0.00e+00	1070.00
IUUC-Tru-117823	Takifugu rubripes	84.23	0.00e+00	980.00
IUUC-Tsy-119154	Tarsius syrichta	95.74	0.00e+00	1066.00
IUUC-Tni-119968	Tetraodon nigroviridis	83.33	0.00e+00	969.00
IUUC-Tbe-127238	Tupaia belangeri	79.23	0.00e+00	731.00
IUUC-Ttr-129208	Tursiops truncatus	95.65	0.00e+00	1131.00
IUUC-Vpa-130363	Vicugna pacos	85.31	0.00e+00	965.00
IUUC-Xtr-132652	Xenopus tropicalis	83.33	0.00e+00	1002.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence