iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094134

UUCD1 version

UUC-PeM-00028

Ensembl Protein ID

ENSPMAP00000005655.1

UniProt Accession

S4RKC2; S4RKC2_PETMA

Protein Name

Uncharacterized protein

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000005106.1	ENSPMAT00000005679.1	ENSPMAP00000005655.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-18	66.4	12	75
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-11	43.6	111	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v++  f+ah+ivLaa+S++F a+f++el+e++ k++v+++++ +  ++ ll+F+Yt ++
   Q: 12   CDVTLRVDEMDFPAHRIVLAACSDYFCAMFTNELSEKD-KPCVDLQGLTAATMEILLDFVYTETV 75
           9************************************9.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi+ fA++++c dL +aa+ f lkhF+
   Q: 111  PSNCLGIREFAEAHSCMDLQQAAELFSLKHFP 142
           89*****************************6 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

AMNALRKSNT LCDVTLRVDE MDFPAHRIVL AACSDYFCAM FTNELSEKDK PCVDLQGLTA 60
ATMEILLDFV YTETVHVTVE NVQELLPAAC LLQLKGVKQA CCEFLESQLD PSNCLGIREF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCATGAACG CACTGCGCAA GAGCAACACG CTGTGCGACG TGACGCTCCG CGTTGACGAG 60
ATGGACTTCC CTGCTCACCG GATCGTCCTG GCCGCCTGCA GCGACTACTT CTGCGCCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0880--Kelch repeat
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00225--BTB
SM00612--Kelch

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000721	Aegilops tauschii	30.62	3.00e-32	132.00
IUUC-Aml-002301	Ailuropoda melanoleuca	74.23	0.00e+00	805.00
IUUC-Apl-003339	Anas platyrhynchos	74.00	0.00e+00	759.00
IUUC-Aca-004418	Anolis carolinensis	74.36	0.00e+00	808.00
IUUC-Aly-005957	Arabidopsis lyrata	30.84	7.00e-40	157.00
IUUC-Ath-007066	Arabidopsis thaliana	31.03	3.00e-40	158.00
IUUC-Ame-011906	Astyanax mexicanus	60.11	5.00e-180	622.00
IUUC-Bta-012979	Bos taurus	73.27	0.00e+00	791.00
IUUC-Cja-019582	Callithrix jacchus	74.18	0.00e+00	805.00
IUUC-Cfa-020716	Canis familiaris	74.36	0.00e+00	807.00
IUUC-Cpo-022013	Cavia porcellus	74.36	0.00e+00	808.00
IUUC-Csa-023424	Chlorocebus sabaeus	72.85	0.00e+00	731.00
IUUC-Cho-024586	Choloepus hoffmanni	87.89	4.00e-151	526.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	29.27	7.00e-22	96.30
IUUC-Dno-028854	Dasypus novemcinctus	74.36	0.00e+00	808.00
IUUC-Dor-030403	Dipodomys ordii	74.18	0.00e+00	803.00
IUUC-Ete-032963	Echinops telfairi	71.34	0.00e+00	699.00
IUUC-Eca-033282	Equus caballus	74.55	0.00e+00	808.00
IUUC-Eeu-034933	Erinaceus europaeus	88.10	3.00e-130	457.00
IUUC-Fca-035487	Felis catus	74.36	0.00e+00	808.00
IUUC-Fal-037059	Ficedula albicollis	75.09	0.00e+00	815.00
IUUC-Gmo-039564	Gadus morhua	72.41	0.00e+00	803.00
IUUC-Gga-040629	Gallus gallus	74.91	0.00e+00	812.00
IUUC-Gac-042526	Gasterosteus aculeatus	72.60	0.00e+00	802.00
IUUC-Ggo-044839	Gorilla gorilla	74.36	0.00e+00	808.00
IUUC-Hsa-046742	Homo sapiens	74.36	0.00e+00	808.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	74.18	0.00e+00	805.00
IUUC-Lch-049540	Latimeria chalumnae	73.68	0.00e+00	830.00
IUUC-Loc-051923	Lepisosteus oculatus	73.87	0.00e+00	801.00
IUUC-Laf-054370	Loxodonta africana	74.00	0.00e+00	806.00
IUUC-Mcc-054852	Macaca mulatta	74.36	0.00e+00	808.00
IUUC-Mor-057181	Magnaporthe oryzae	27.97	3.00e-12	64.30
IUUC-Mga-059486	Meleagris gallopavo	72.23	0.00e+00	746.00
IUUC-Mvi-060512	Microbotryum violaceum	23.98	3.00e-06	46.20
IUUC-Mmr-061777	Microcebus murinus	74.23	0.00e+00	807.00
IUUC-Mdo-061990	Monodelphis domestica	73.82	0.00e+00	802.00
IUUC-Mmu-064053	Mus musculus	74.36	0.00e+00	808.00
IUUC-Mpu-066623	Mustela putorius furo	59.66	1.00e-144	505.00
IUUC-Mlu-067648	Myotis lucifugus	74.05	0.00e+00	829.00
IUUC-Nle-069714	Nomascus leucogenys	74.36	0.00e+00	808.00
IUUC-Opr-071143	Ochotona princeps	68.18	0.00e+00	714.00
IUUC-Ont-071848	Oreochromis niloticus	72.60	0.00e+00	805.00
IUUC-Ocu-074379	Oryctolagus cuniculus	74.36	0.00e+00	807.00
IUUC-Ola-087469	Oryzias latipes	72.41	0.00e+00	804.00
IUUC-Oar-090144	Ovis aries	73.87	0.00e+00	801.00
IUUC-Ptr-091406	Pan troglodytes	74.36	0.00e+00	808.00
IUUC-Pan-092762	Papio anubis	73.19	0.00e+00	788.00
IUUC-Psi-093391	Pelodiscus sinensis	74.18	0.00e+00	807.00
IUUC-Pfo-096404	Poecilia formosa	72.96	0.00e+00	806.00
IUUC-Pab-098425	Pongo abelii	73.45	0.00e+00	799.00
IUUC-Pca-101093	Procavia capensis	62.50	4.00e-96	343.00
IUUC-Pva-102239	Pteropus vampyrus	66.18	0.00e+00	705.00
IUUC-Rno-104921	Rattus norvegicus	74.18	0.00e+00	808.00
IUUC-Sha-106625	Sarcophilus harrisii	74.73	0.00e+00	810.00
IUUC-Ssc-116106	Sus scrofa	74.55	0.00e+00	806.00
IUUC-Tgu-117402	Taeniopygia guttata	55.43	1.00e-147	514.00
IUUC-Tru-117546	Takifugu rubripes	72.60	0.00e+00	806.00
IUUC-Tsy-118802	Tarsius syrichta	65.21	0.00e+00	671.00
IUUC-Tni-119999	Tetraodon nigroviridis	72.96	0.00e+00	806.00
IUUC-Tca-121074	Theobroma cacao	30.11	3.00e-36	145.00
IUUC-Tbe-127987	Tupaia belangeri	71.27	0.00e+00	640.00
IUUC-Ttr-128613	Tursiops truncatus	88.50	1.00e-152	531.00
IUUC-Uma-129385	Ustilago maydis	30.77	1.90e-02	34.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence