iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091374

UUCD1 version

UUC-PaT-00840

Ensembl Protein ID

ENSPTRP00000045260.2

UniProt Accession

H2R3C0; H2R3C0_PANTR

Genbank Protein ID

JAA01039.1; JAA13654.1; JAA24412.1

Protein Name

Ring finger protein 121

Genbank Nucleotide ID

AACZ03079532; GABF01008491; GABD01008688

Gene Name

RNF121

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000004021.5	ENSPTRT00000048821.2	ENSPTRP00000045260.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-07	32.0	226	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 226  CAVCGQQIfvdvseegiiEN-TYRLSCNHVFHEFCIRGW----CIVGKKQTCPYCK 276
           9***9888888887777655.777***************....889999******7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAAVVEVEVG GGAAGERELD EVDMSDLSPE EQWRVEHARM HAKHRGHEAM HAEMVLILIA 60
TLVVAQLLLV QWKQRHPRSY NMVTLFQMWV VPLYFTVKLH WWRFLVIWIL FSAVTAFVTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACTGAGGG AGCGTCGCGA AAGTTGCCCG TTTTGGAACG CTCCCATTTG GCTCTCCAAA 60
GGGAAGAATT GGTTAAATAG TTGCACTGAA AATAATGCGA TTCAAATTTC TCATTTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002350	Ailuropoda melanoleuca	98.71	3.00e-175	607.00
IUUC-Apl-003882	Anas platyrhynchos	86.82	2.00e-140	491.00
IUUC-Aca-004343	Anolis carolinensis	89.13	1.00e-22	97.10
IUUC-Aly-005550	Arabidopsis lyrata	37.10	2.00e-06	47.40
IUUC-Ame-010680	Astyanax mexicanus	83.73	5.00e-161	560.00
IUUC-Bta-013045	Bos taurus	99.32	1.00e-166	578.00
IUUC-Cel-018296	Caenorhabditis elegans	51.58	2.00e-99	355.00
IUUC-Cja-019866	Callithrix jacchus	99.03	8.00e-176	609.00
IUUC-Cfa-021176	Canis familiaris	97.76	3.00e-174	603.00
IUUC-Cpo-022268	Cavia porcellus	97.73	2.00e-172	597.00
IUUC-Cre-022649	Chlamydomonas reinhardtii	41.06	8.00e-55	206.00
IUUC-Csa-023727	Chlorocebus sabaeus	99.68	3.00e-176	610.00
IUUC-Cho-025016	Choloepus hoffmanni	99.04	6.00e-177	612.00
IUUC-Cin-025281	Ciona intestinalis	64.24	4.00e-125	440.00
IUUC-Csv-026338	Ciona savignyi	63.99	3.00e-113	401.00
IUUC-Dre-027836	Danio rerio	82.08	5.00e-143	500.00
IUUC-Dno-029737	Dasypus novemcinctus	97.76	6.00e-174	602.00
IUUC-Dor-031070	Dipodomys ordii	91.48	7.00e-155	539.00
IUUC-Dme-031867	Drosophila melanogaster	60.00	2.00e-113	402.00
IUUC-Ete-032964	Echinops telfairi	89.71	5.00e-166	576.00
IUUC-Eca-034398	Equus caballus	99.35	9.00e-176	608.00
IUUC-Fca-035807	Felis catus	99.03	4.00e-173	600.00
IUUC-Fal-036721	Ficedula albicollis	95.83	1.00e-158	551.00
IUUC-Gmo-039699	Gadus morhua	87.99	8.00e-150	522.00
IUUC-Gga-040840	Gallus gallus	96.25	2.00e-161	560.00
IUUC-Gac-042639	Gasterosteus aculeatus	83.13	3.00e-150	524.00
IUUC-Ggo-045576	Gorilla gorilla	100.00	3.00e-174	603.00
IUUC-Hsa-046468	Homo sapiens	100.00	1.00e-176	611.00
IUUC-Itr-048638	Ictidomys tridecemlineatus	98.78	6.00e-147	512.00
IUUC-Lch-050207	Latimeria chalumnae	82.14	1.00e-143	501.00
IUUC-Loc-052172	Lepisosteus oculatus	89.25	2.00e-160	558.00
IUUC-Laf-053879	Loxodonta africana	98.40	1.00e-176	612.00
IUUC-Mcc-055492	Macaca mulatta	99.68	3.00e-176	610.00
IUUC-Meu-055976	Macropus eugenii	82.35	3.00e-138	483.00
IUUC-Mga-059989	Meleagris gallopavo	93.97	7.00e-169	585.00
IUUC-Mmr-060894	Microcebus murinus	99.68	3.00e-176	610.00
IUUC-Mdo-061826	Monodelphis domestica	95.41	4.00e-166	577.00
IUUC-Mmu-063717	Mus musculus	98.70	3.00e-174	603.00
IUUC-Mpu-066826	Mustela putorius furo	99.35	5.00e-176	609.00
IUUC-Mlu-068081	Myotis lucifugus	95.11	4.00e-175	606.00
IUUC-Nle-069734	Nomascus leucogenys	99.68	3.00e-176	610.00
IUUC-Opr-070379	Ochotona princeps	95.82	2.00e-168	584.00
IUUC-Ont-071855	Oreochromis niloticus	83.13	1.00e-150	525.00
IUUC-Ocu-074363	Oryctolagus cuniculus	99.04	2.00e-176	611.00
IUUC-Ola-086489	Oryzias latipes	81.63	1.00e-148	518.00
IUUC-Oga-088323	Otolemur garnettii	99.35	5.00e-173	599.00
IUUC-Oar-090243	Ovis aries	98.39	6.00e-176	609.00
IUUC-Pan-092115	Papio anubis	99.68	3.00e-176	610.00
IUUC-Psi-093658	Pelodiscus sinensis	95.68	6.00e-154	536.00
IUUC-Pfo-097261	Poecilia formosa	82.23	4.00e-149	520.00
IUUC-Pab-098579	Pongo abelii	100.00	1.00e-176	611.00
IUUC-Pca-100119	Procavia capensis	93.89	3.00e-161	560.00
IUUC-Pva-102111	Pteropus vampyrus	99.02	4.00e-173	600.00
IUUC-Rno-105364	Rattus norvegicus	98.39	8.00e-176	608.00
IUUC-Sha-107005	Sarcophilus harrisii	95.50	9.00e-173	598.00
IUUC-Sar-113163	Sorex araneus	99.35	4.00e-176	610.00
IUUC-Ssc-115633	Sus scrofa	95.60	3.00e-173	600.00
IUUC-Tgu-116869	Taeniopygia guttata	97.28	9.00e-164	568.00
IUUC-Tru-118217	Takifugu rubripes	81.55	7.00e-157	546.00
IUUC-Tsy-119308	Tarsius syrichta	99.03	2.00e-175	607.00
IUUC-Tni-119882	Tetraodon nigroviridis	83.18	4.00e-158	550.00
IUUC-Ttr-129087	Tursiops truncatus	99.35	3.00e-174	603.00
IUUC-Vpa-130785	Vicugna pacos	92.93	6.00e-163	566.00
IUUC-Xtr-132801	Xenopus tropicalis	90.83	1.00e-156	545.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence