iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034162

UUCD1 version

UUC-EqC-00057

Ensembl Protein ID

ENSECAP00000015735.1

UniProt Accession

F6QCL2; F6QCL2_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000017829.1	ENSECAT00000019240.1	ENSECAP00000015735.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.30e-17	62.8	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-09	36.8	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 66   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 165  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 196
           89*****************************7 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MASESMNAKQ ARNHFTKGKK QQQQQVKNKS SVSDGAGEDS FIFEANEAWK DFHSSLLRFY 60
ENGELCDVTL KVGSKLISCH KLVLACVIPY FRAMFLSEMA EAKQTLIEIR DFDGDAIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCAAACTG GACAAAGGCA CTTGCGTGGG TTTTGAAAAA TGTCTGAAGT TTAGTGGGCT 60
CCATCCACCT TCTGCCTTCT CCCCACCCTT TACAAAAGAA TAAATGGGAT GTTCGAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ecb:100062841

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	97.74	0.00e+00	1218.00
IUUC-Atr-002726	Amborella trichopoda	35.48	5.00e-43	169.00
IUUC-Apl-003978	Anas platyrhynchos	89.82	0.00e+00	1158.00
IUUC-Aca-004958	Anolis carolinensis	85.81	0.00e+00	1074.00
IUUC-Ame-011139	Astyanax mexicanus	85.91	0.00e+00	1068.00
IUUC-Bta-013142	Bos taurus	96.28	0.00e+00	1205.00
IUUC-Bdi-014143	Brachypodium distachyon	39.58	3.00e-43	170.00
IUUC-Bol-015710	Brassica oleracea	25.75	2.00e-11	63.20
IUUC-Cel-018551	Caenorhabditis elegans	41.25	4.00e-131	461.00
IUUC-Cja-019650	Callithrix jacchus	96.13	0.00e+00	1231.00
IUUC-Cfa-021046	Canis familiaris	97.58	0.00e+00	1217.00
IUUC-Cpo-022445	Cavia porcellus	94.67	0.00e+00	1159.00
IUUC-Csa-023642	Chlorocebus sabaeus	96.94	0.00e+00	1237.00
IUUC-Cho-025012	Choloepus hoffmanni	79.55	0.00e+00	890.00
IUUC-Dre-027723	Danio rerio	82.85	0.00e+00	1054.00
IUUC-Dno-028964	Dasypus novemcinctus	95.31	0.00e+00	1002.00
IUUC-Dor-030899	Dipodomys ordii	84.11	1.00e-137	483.00
IUUC-Ete-032815	Echinops telfairi	93.38	0.00e+00	1190.00
IUUC-Eeu-034660	Erinaceus europaeus	94.51	0.00e+00	1184.00
IUUC-Fca-035659	Felis catus	98.06	0.00e+00	1222.00
IUUC-Fal-037619	Ficedula albicollis	90.31	0.00e+00	1156.00
IUUC-Gmo-038546	Gadus morhua	85.22	0.00e+00	1054.00
IUUC-Gga-040770	Gallus gallus	89.68	0.00e+00	1134.00
IUUC-Gac-042557	Gasterosteus aculeatus	82.03	0.00e+00	1039.00
IUUC-Ggo-044741	Gorilla gorilla	96.94	0.00e+00	1238.00
IUUC-Hsa-046025	Homo sapiens	96.77	0.00e+00	1236.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	98.36	0.00e+00	1110.00
IUUC-Loc-052834	Lepisosteus oculatus	87.22	0.00e+00	1015.00
IUUC-Laf-054513	Loxodonta africana	96.77	0.00e+00	1209.00
IUUC-Mcc-054707	Macaca mulatta	96.77	0.00e+00	1232.00
IUUC-Meu-056779	Macropus eugenii	94.47	0.00e+00	1158.00
IUUC-Mtr-058180	Medicago truncatula	31.20	9.00e-36	145.00
IUUC-Mga-059676	Meleagris gallopavo	89.52	0.00e+00	1132.00
IUUC-Mmr-061359	Microcebus murinus	95.65	0.00e+00	1188.00
IUUC-Mdo-062527	Monodelphis domestica	92.54	0.00e+00	1151.00
IUUC-Mmu-063112	Mus musculus	92.85	0.00e+00	1197.00
IUUC-Mac-064682	Musa acuminata	36.36	3.00e-42	166.00
IUUC-Mpu-065800	Mustela putorius furo	97.25	0.00e+00	1215.00
IUUC-Mlu-067536	Myotis lucifugus	96.09	0.00e+00	1161.00
IUUC-Nle-069397	Nomascus leucogenys	96.94	0.00e+00	1237.00
IUUC-Opr-070599	Ochotona princeps	95.69	0.00e+00	1003.00
IUUC-Ont-072580	Oreochromis niloticus	84.02	0.00e+00	1049.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.76	0.00e+00	1174.00
IUUC-Ocu-074026	Oryctolagus cuniculus	97.42	0.00e+00	1209.00
IUUC-Obr-076181	Oryza brachyantha	32.03	6.00e-36	146.00
IUUC-Ola-086776	Oryzias latipes	83.16	0.00e+00	1004.00
IUUC-Oga-088651	Otolemur garnettii	97.26	0.00e+00	1211.00
IUUC-Oar-089567	Ovis aries	95.15	0.00e+00	1179.00
IUUC-Ptr-091564	Pan troglodytes	96.94	0.00e+00	1238.00
IUUC-Pan-092578	Papio anubis	96.94	0.00e+00	1237.00
IUUC-Psi-093635	Pelodiscus sinensis	89.60	0.00e+00	1089.00
IUUC-Pma-094660	Petromyzon marinus	61.82	0.00e+00	761.00
IUUC-Pfo-097507	Poecilia formosa	83.39	0.00e+00	979.00
IUUC-Pab-098025	Pongo abelii	96.94	0.00e+00	1238.00
IUUC-Pca-101046	Procavia capensis	87.67	0.00e+00	636.00
IUUC-Ppe-101154	Prunus persica	33.33	3.00e-38	153.00
IUUC-Pva-102359	Pteropus vampyrus	98.18	0.00e+00	909.00
IUUC-Rno-105750	Rattus norvegicus	93.40	0.00e+00	1184.00
IUUC-Sha-107513	Sarcophilus harrisii	91.77	0.00e+00	1170.00
IUUC-Sly-111482	Solanum lycopersicum	31.91	1.00e-41	164.00
IUUC-Stu-112032	Solanum tuberosum	33.07	5.00e-43	169.00
IUUC-Sar-113616	Sorex araneus	70.99	2.00e-118	419.00
IUUC-Ssc-116205	Sus scrofa	96.68	0.00e+00	1013.00
IUUC-Tgu-117435	Taeniopygia guttata	90.95	0.00e+00	1158.00
IUUC-Tru-118709	Takifugu rubripes	83.16	0.00e+00	1043.00
IUUC-Tsy-119466	Tarsius syrichta	99.09	0.00e+00	1111.00
IUUC-Tni-119988	Tetraodon nigroviridis	83.02	0.00e+00	1040.00
IUUC-Tae-124761	Triticum aestivum	34.80	5.00e-39	156.00
IUUC-Tbe-127704	Tupaia belangeri	97.08	0.00e+00	1070.00
IUUC-Ttr-128892	Tursiops truncatus	98.49	0.00e+00	929.00
IUUC-Vpa-130545	Vicugna pacos	97.65	0.00e+00	1020.00
IUUC-Xtr-132289	Xenopus tropicalis	83.48	0.00e+00	1016.00
IUUC-Xma-133419	Xiphophorus maculatus	83.84	0.00e+00	952.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence