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Tag Content
UUCD2 ID IUUC-Ocu-074477
UUCD1 version UUC-OrC-00280
Ensembl Protein ID ENSOCUP00000017473.2
UniProt Accession G1TKI7; G1TKI7_RABIT
Genbank Protein ID ENSOCUP00000017473
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAGW02063922
Gene Name FBXW8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000014685.3 ENSOCUT00000024914.2 ENSOCUP00000017473.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-13 50.9 366 396
UBD/Beta-Prp 4.50e-42 144.3 100 399
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           H+ +v++++ +d+ +vsG+  g + vWD+r 
   Q: 366  HQLGVSAVQMDDWKIVSGGEEGLVSVWDYRM 396
           7778999999669***************875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheae....vtavkfspdgkilvtgseDrtikvwdlstgkcv 87
            +++v+++v+   ++ ++++g+++g ++vwd++t+++      ++++++e++    v+ v+++++  + v + eD+++++wdl+tg + 
   Q: 100  VPDAVLCDVHS--HDGVVVAGYTSGDVRVWDTRTWDYvapflESEFEEDEPGmqpyVSFVRINSS--LAVAAYEDGFLNIWDLRTGRYP 184
           57889997777..9***********************6666544555555559999*********..9********************9 PP
   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl 175
           ++  +h++++ +l++s++g +++++s+  +i+++  e+g++  +t+ + +++v ++++ pd+ +  v+ ++ + + ++ lk ++  rtl
   Q: 185  IHRFEHDARIQALALSRKGATVATASAFGVIMLYPNEEGYWQMATEFEVQKLVDYLEIVPDTgRFPVAIAAAGDL-VYLLKAEDSARTL 272
           99999*********************************************************9999999999998.5************ PP
   S: 176  tgghtdsvyslsfdsng.....kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdlrsgdllk 258
                ++v++l+++ n+     k+l ++ + +++ +++l++++c+ +l +    +++v++  +   ++vsg++D+ +ri+dlr++++  
   Q: 273  HYVYGQPVTCLDVSANQvafgvKSLGWVYEGNKILVYSLEAERCLSKLGNALGDFTCVNLRdSPPSLMVSGNMDRRVRIHDLRTDKIAL 361
           999********************************************************996788999********************* PP
   S: 259  tlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +l+ h+  v++v++   +d+++v+g+e++ v +w++++n++
   Q: 362  SLSAHQLGVSAVQM---DDWKIVSGGEEGLVSVWDYRMNQK 399
           ******99999999...********************9875 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MDDVPFFDVQ LPYELAINIF QYLGRKELGR CAQVSKTWKV IAEDEVLWYR LCQQEGHLLE 60
SSISDYSCWK LVFQECRARE HMLRTNWKNR KGAVSELEPV PDAVLCDVHS HDGVVVAGYT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074477|E3,WD_repeat;UBD,Beta-Prp|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AACGAAATGG ATGATGTGCC CTTCTTCGAT GTCCAGCTGC CTTATGAATT GGCCATCAAC 60
ATATTTCAGT ATCTGGGCAG GAAAGAACTA GGACGGTGTG CGCAGGTAAG CTATGGTTAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074477|E3,WD_repeat;UBD,Beta-Prp|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12937--F-box-like
SMART

SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0060716--P:labyrinthine layer blood vessel development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0060712--P:spongiotrophoblast layer development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001274 Ailuropoda melanoleuca 90.72 0.00e+00 931.00
IUUC-Apl-003239 Anas platyrhynchos 65.30 0.00e+00 684.00
IUUC-Aca-004756 Anolis carolinensis 61.50 2.00e-136 478.00
IUUC-Ame-011198 Astyanax mexicanus 54.07 4.00e-51 194.00
IUUC-Bta-012430 Bos taurus 56.29 4.00e-142 498.00
IUUC-Cja-019131 Callithrix jacchus 82.89 0.00e+00 824.00
IUUC-Cfa-021022 Canis familiaris 90.72 0.00e+00 932.00
IUUC-Cpo-021898 Cavia porcellus 90.52 0.00e+00 927.00
IUUC-Csa-023452 Chlorocebus sabaeus 85.36 0.00e+00 860.00
IUUC-Cho-024759 Choloepus hoffmanni 78.14 0.00e+00 770.00
IUUC-Dre-028123 Danio rerio 50.51 8.00e-143 500.00
IUUC-Dno-029045 Dasypus novemcinctus 91.59 0.00e+00 866.00
IUUC-Dor-030433 Dipodomys ordii 90.46 0.00e+00 779.00
IUUC-Ete-032465 Echinops telfairi 89.63 0.00e+00 775.00
IUUC-Eca-034134 Equus caballus 90.52 0.00e+00 930.00
IUUC-Eeu-035047 Erinaceus europaeus 79.39 0.00e+00 803.00
IUUC-Fca-036574 Felis catus 89.90 0.00e+00 917.00
IUUC-Fal-037665 Ficedula albicollis 62.42 5.00e-178 617.00
IUUC-Gmo-039137 Gadus morhua 45.53 1.00e-59 223.00
IUUC-Gga-040711 Gallus gallus 64.89 0.00e+00 670.00
IUUC-Gac-041675 Gasterosteus aculeatus 54.89 4.00e-54 203.00
IUUC-Ggo-045331 Gorilla gorilla 84.95 0.00e+00 856.00
IUUC-Hsa-046240 Homo sapiens 85.57 0.00e+00 865.00
IUUC-Itr-048412 Ictidomys tridecemlineatus 91.55 0.00e+00 913.00
IUUC-Loc-052631 Lepisosteus oculatus 55.33 3.00e-164 572.00
IUUC-Laf-054127 Loxodonta africana 79.71 9.00e-60 221.00
IUUC-Mcc-055083 Macaca mulatta 85.36 0.00e+00 865.00
IUUC-Mga-060113 Meleagris gallopavo 64.68 0.00e+00 670.00
IUUC-Mmr-061780 Microcebus murinus 90.74 0.00e+00 927.00
IUUC-Mdo-063066 Monodelphis domestica 67.70 0.00e+00 704.00
IUUC-Mmu-063524 Mus musculus 85.98 0.00e+00 853.00
IUUC-Mpu-066913 Mustela putorius furo 90.52 0.00e+00 923.00
IUUC-Mlu-067924 Myotis lucifugus 88.19 0.00e+00 885.00
IUUC-Nle-069558 Nomascus leucogenys 85.16 0.00e+00 821.00
IUUC-Opr-070506 Ochotona princeps 92.86 0.00e+00 950.00
IUUC-Ont-071514 Oreochromis niloticus 48.98 3.00e-138 485.00
IUUC-Ola-087416 Oryzias latipes 49.08 1.00e-136 479.00
IUUC-Oga-088643 Otolemur garnettii 91.34 0.00e+00 937.00
IUUC-Oar-090172 Ovis aries 90.93 0.00e+00 926.00
IUUC-Ptr-090870 Pan troglodytes 85.77 0.00e+00 866.00
IUUC-Pan-092017 Papio anubis 84.95 0.00e+00 855.00
IUUC-Psi-093794 Pelodiscus sinensis 66.12 0.00e+00 674.00
IUUC-Pfo-096192 Poecilia formosa 51.22 3.00e-143 501.00
IUUC-Pab-097882 Pongo abelii 84.95 0.00e+00 852.00
IUUC-Pca-100902 Procavia capensis 88.98 1.00e-129 456.00
IUUC-Pva-103139 Pteropus vampyrus 90.52 0.00e+00 930.00
IUUC-Rno-105798 Rattus norvegicus 85.57 0.00e+00 871.00
IUUC-Sha-106576 Sarcophilus harrisii 68.05 0.00e+00 699.00
IUUC-Ssc-115923 Sus scrofa 81.52 0.00e+00 835.00
IUUC-Tgu-116667 Taeniopygia guttata 57.99 2.00e-119 422.00
IUUC-Tru-118323 Takifugu rubripes 47.65 6.00e-134 471.00
IUUC-Tsy-118818 Tarsius syrichta 77.11 2.00e-107 382.00
IUUC-Tni-120438 Tetraodon nigroviridis 47.24 1.00e-126 446.00
IUUC-Tbe-127784 Tupaia belangeri 94.66 2.00e-113 402.00
IUUC-Ttr-128288 Tursiops truncatus 80.21 0.00e+00 800.00
IUUC-Vpa-130307 Vicugna pacos 85.75 0.00e+00 789.00
Created Date 25-Jun-2017

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