iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045307

UUCD1 version

UUC-GoG-00529

Ensembl Protein ID

ENSGGOP00000013409.2

UniProt Accession

G3RD17; G3RD17_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000013748.2	ENSGGOT00000013795.2	ENSGGOP00000013409.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.60e-09	37.9	10	60
E3 activity/RING/U-box	3.40e-06	27.4	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENI----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....567777766666666777****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           ee+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    EELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNfyiwrplriplKCPNCRSITeiaptGVESLPVNFALRAIIEKYQQE 89
           7999*****************************999999**********99999975533321445666689999999999776 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MHNFEEELTC PICYSIFEDP RVLPCSHTFC RNCLENILQA SGNFYIWRPL RIPLKCPNCR 60
SITEIAPTGV ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCGGAGCG GAGGAGGGCG GGGACTCGGG GCGGCTCTCA GCATCCGCCT GGAGATCGTG 60
GCGCTGTGTT TCCGTGCTGT GGAGTTGCCT GGTCCGCTTC CTCCCCGCGG TGAGTCTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

ggo:101123824

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	87.81	0.00e+00	738.00
IUUC-Apl-003996	Anas platyrhynchos	58.52	3.00e-123	434.00
IUUC-Aca-005141	Anolis carolinensis	56.82	9.00e-132	463.00
IUUC-Ame-011353	Astyanax mexicanus	52.12	1.00e-98	353.00
IUUC-Bta-013440	Bos taurus	88.95	0.00e+00	670.00
IUUC-Cja-019076	Callithrix jacchus	90.54	5.00e-176	611.00
IUUC-Cfa-021168	Canis familiaris	88.06	0.00e+00	738.00
IUUC-Cpo-021702	Cavia porcellus	75.44	3.00e-176	610.00
IUUC-Csa-024141	Chlorocebus sabaeus	94.29	0.00e+00	719.00
IUUC-Dre-028408	Danio rerio	46.69	2.00e-87	315.00
IUUC-Dno-029180	Dasypus novemcinctus	86.85	0.00e+00	722.00
IUUC-Ete-033028	Echinops telfairi	85.22	2.00e-164	573.00
IUUC-Eca-034357	Equus caballus	87.34	0.00e+00	704.00
IUUC-Eeu-034909	Erinaceus europaeus	79.68	1.00e-152	533.00
IUUC-Fca-036287	Felis catus	88.59	0.00e+00	741.00
IUUC-Gmo-038657	Gadus morhua	43.69	1.00e-64	241.00
IUUC-Gga-040739	Gallus gallus	57.88	1.00e-135	476.00
IUUC-Gac-041586	Gasterosteus aculeatus	47.00	3.00e-93	336.00
IUUC-Hsa-045690	Homo sapiens	98.26	0.00e+00	782.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	89.33	0.00e+00	749.00
IUUC-Loc-052774	Lepisosteus oculatus	51.66	9.00e-103	368.00
IUUC-Laf-054522	Loxodonta africana	84.37	0.00e+00	705.00
IUUC-Mcc-055145	Macaca mulatta	94.29	0.00e+00	752.00
IUUC-Meu-056214	Macropus eugenii	47.77	4.00e-61	228.00
IUUC-Mmr-061197	Microcebus murinus	90.57	0.00e+00	758.00
IUUC-Mdo-062631	Monodelphis domestica	59.51	7.00e-135	473.00
IUUC-Mmu-064217	Mus musculus	82.34	0.00e+00	664.00
IUUC-Mpu-065691	Mustela putorius furo	89.83	0.00e+00	753.00
IUUC-Mlu-067742	Myotis lucifugus	84.79	0.00e+00	681.00
IUUC-Nle-069722	Nomascus leucogenys	95.29	0.00e+00	789.00
IUUC-Oan-073382	Ornithorhynchus anatinus	61.04	6.00e-139	486.00
IUUC-Ocu-073896	Oryctolagus cuniculus	88.01	1.00e-167	583.00
IUUC-Ola-086767	Oryzias latipes	45.28	2.00e-79	290.00
IUUC-Oar-089206	Ovis aries	86.85	0.00e+00	729.00
IUUC-Pan-092189	Papio anubis	94.54	0.00e+00	754.00
IUUC-Psi-093523	Pelodiscus sinensis	62.07	3.00e-143	501.00
IUUC-Pma-094162	Petromyzon marinus	31.79	5.00e-46	177.00
IUUC-Pfo-096032	Poecilia formosa	46.91	5.00e-87	314.00
IUUC-Pva-103089	Pteropus vampyrus	87.28	0.00e+00	701.00
IUUC-Pgr-103338	Puccinia graminis	36.23	9.00e-07	47.00
IUUC-Rno-105440	Rattus norvegicus	83.58	0.00e+00	676.00
IUUC-Ssc-115809	Sus scrofa	86.10	0.00e+00	694.00
IUUC-Tru-118402	Takifugu rubripes	43.50	4.00e-93	334.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.16	2.00e-83	302.00
IUUC-Tbe-127434	Tupaia belangeri	86.75	1.00e-161	563.00
IUUC-Ttr-128921	Tursiops truncatus	87.53	0.00e+00	709.00
IUUC-Vpa-130397	Vicugna pacos	87.34	0.00e+00	737.00
IUUC-Xtr-132752	Xenopus tropicalis	42.66	2.00e-84	305.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence