iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036834

Ensembl Protein ID

ENSFALP00000012982.1

UniProt Accession

U3KD78; U3KD78_FICAL

Genbank Protein ID

ENSFALP00000012982

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021188

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012435.1	ENSFALT00000013034.1	ENSFALP00000012982.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	73.67	0.00e+00	734.00	IUUC-Hsa-046349
E3 activity/RING/RING	73.25	0.00e+00	729.00	IUUC-Mmu-063780

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MALREAVQTP CGHRFCKGCI VKSIRDAGHK CPVDNEILLE NQLFPDNFAK REILSLMVKC 60
PNKGCSMKME LRHLEDHQLQ CDFSTVECPQ CQGAFPKNYL KEHMTQECPR RQVCCPNCAT 120

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Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG TGCGGCGCCG CGGGCGGCTC CTGCGGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0009887--P:animal organ morphogenesis
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001262	Ailuropoda melanoleuca	75.32	0.00e+00	731.00
IUUC-Apl-004062	Anas platyrhynchos	94.93	0.00e+00	942.00
IUUC-Aca-004636	Anolis carolinensis	78.13	0.00e+00	778.00
IUUC-Ame-011682	Astyanax mexicanus	54.70	2.00e-148	518.00
IUUC-Bta-012692	Bos taurus	75.00	0.00e+00	741.00
IUUC-Cja-019426	Callithrix jacchus	73.67	0.00e+00	719.00
IUUC-Cfa-020948	Canis familiaris	75.42	0.00e+00	654.00
IUUC-Cpo-021378	Cavia porcellus	75.21	0.00e+00	739.00
IUUC-Csa-024045	Chlorocebus sabaeus	73.67	0.00e+00	734.00
IUUC-Cho-024973	Choloepus hoffmanni	63.22	2.00e-62	233.00
IUUC-Cin-025234	Ciona intestinalis	30.62	2.00e-64	239.00
IUUC-Csv-026300	Ciona savignyi	39.59	2.00e-37	148.00
IUUC-Dre-027557	Danio rerio	60.08	2.00e-164	572.00
IUUC-Dno-030032	Dasypus novemcinctus	70.70	1.00e-101	362.00
IUUC-Dor-030790	Dipodomys ordii	74.10	0.00e+00	731.00
IUUC-Dme-031921	Drosophila melanogaster	26.67	1.00e-35	144.00
IUUC-Ete-032952	Echinops telfairi	71.14	1.00e-147	516.00
IUUC-Eca-033924	Equus caballus	70.19	0.00e+00	657.00
IUUC-Eeu-034734	Erinaceus europaeus	65.68	0.00e+00	627.00
IUUC-Fca-036222	Felis catus	66.60	0.00e+00	633.00
IUUC-Fox-037935	Fusarium oxysporum	31.25	3.00e-20	92.80
IUUC-Gmo-039061	Gadus morhua	61.03	3.00e-75	275.00
IUUC-Gga-040599	Gallus gallus	95.32	0.00e+00	945.00
IUUC-Gac-041977	Gasterosteus aculeatus	56.53	4.00e-161	560.00
IUUC-Ggo-044508	Gorilla gorilla	68.92	0.00e+00	662.00
IUUC-Hsa-046349	Homo sapiens	73.67	0.00e+00	734.00
IUUC-Hvu-047127	Hordeum vulgare	36.00	8.00e-08	50.80
IUUC-Itr-047966	Ictidomys tridecemlineatus	73.57	0.00e+00	737.00
IUUC-Lch-049821	Latimeria chalumnae	72.71	0.00e+00	723.00
IUUC-Lpe-051100	Leersia perrieri	34.67	2.00e-06	46.20
IUUC-Loc-051995	Lepisosteus oculatus	61.35	1.00e-174	605.00
IUUC-Laf-054115	Loxodonta africana	73.89	0.00e+00	728.00
IUUC-Mcc-055298	Macaca mulatta	73.46	0.00e+00	731.00
IUUC-Mor-057263	Magnaporthe oryzae	31.43	9.00e-19	88.20
IUUC-Mga-059340	Meleagris gallopavo	95.74	0.00e+00	949.00
IUUC-Mvi-060553	Microbotryum violaceum	28.50	2.00e-16	80.10
IUUC-Mmr-061063	Microcebus murinus	75.16	0.00e+00	749.00
IUUC-Mdo-062075	Monodelphis domestica	73.22	0.00e+00	729.00
IUUC-Mmu-063780	Mus musculus	73.25	0.00e+00	726.00
IUUC-Mpu-065748	Mustela putorius furo	75.80	0.00e+00	732.00
IUUC-Mlu-067888	Myotis lucifugus	73.89	0.00e+00	733.00
IUUC-Ncr-068632	Neurospora crassa	26.67	4.00e-14	73.20
IUUC-Nle-069234	Nomascus leucogenys	73.25	0.00e+00	730.00
IUUC-Opr-070393	Ochotona princeps	79.81	6.00e-104	370.00
IUUC-Ont-072459	Oreochromis niloticus	57.17	1.00e-166	579.00
IUUC-Oan-073578	Ornithorhynchus anatinus	78.42	0.00e+00	790.00
IUUC-Ocu-074201	Oryctolagus cuniculus	73.89	0.00e+00	735.00
IUUC-Oni-083040	Oryza nivara	34.67	7.00e-07	47.40
IUUC-Osa-085740	Oryza sativa	34.67	8.00e-07	47.80
IUUC-Ola-087319	Oryzias latipes	64.32	8.00e-77	281.00
IUUC-Oga-087936	Otolemur garnettii	73.04	0.00e+00	726.00
IUUC-Oar-089379	Ovis aries	74.95	0.00e+00	741.00
IUUC-Ptr-090758	Pan troglodytes	73.46	0.00e+00	733.00
IUUC-Pan-092590	Papio anubis	73.46	0.00e+00	731.00
IUUC-Psi-093948	Pelodiscus sinensis	84.93	0.00e+00	853.00
IUUC-Pma-094434	Petromyzon marinus	45.36	9.00e-117	414.00
IUUC-Pfo-096912	Poecilia formosa	56.42	1.00e-161	563.00
IUUC-Pab-097651	Pongo abelii	73.46	0.00e+00	733.00
IUUC-Pca-100958	Procavia capensis	70.45	8.00e-170	589.00
IUUC-Pva-103247	Pteropus vampyrus	77.53	2.00e-82	299.00
IUUC-Rno-104994	Rattus norvegicus	73.67	0.00e+00	729.00
IUUC-Sha-106494	Sarcophilus harrisii	75.80	0.00e+00	746.00
IUUC-Smo-108702	Selaginella moellendorffii	47.06	3.00e-04	38.10
IUUC-Sar-113375	Sorex araneus	75.64	0.00e+00	742.00
IUUC-Sre-115218	Sporisorium reilianum	35.37	2.00e-16	80.90
IUUC-Ssc-115417	Sus scrofa	76.38	0.00e+00	751.00
IUUC-Tgu-117232	Taeniopygia guttata	97.24	0.00e+00	966.00
IUUC-Tru-118321	Takifugu rubripes	57.35	5.00e-163	567.00
IUUC-Tni-120475	Tetraodon nigroviridis	57.08	2.00e-158	552.00
IUUC-Tur-126067	Triticum urartu	32.46	3.00e-08	52.40
IUUC-Tbe-127719	Tupaia belangeri	62.79	3.00e-169	587.00
IUUC-Ttr-129264	Tursiops truncatus	79.21	9.00e-84	303.00
IUUC-Uma-129620	Ustilago maydis	25.25	7.00e-14	72.40
IUUC-Vpa-130244	Vicugna pacos	79.21	1.00e-83	303.00
IUUC-Xtr-131948	Xenopus tropicalis	71.58	0.00e+00	704.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence