iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044552

UUCD1 version

UUC-GoG-01062

Ensembl Protein ID

ENSGGOP00000022335.1

UniProt Accession

G3S2N7; G3S2N7_GORGO

Protein Name

Uncharacterized protein

Gene Name

OTUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000012111.2	ENSGGOT00000012156.2	ENSGGOP00000011815.2
ENSGGOG00000012111.2	ENSGGOT00000029897.1	ENSGGOP00000022335.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	2.70e-43	148.1	146	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 20   s........llgvfdddslsdalveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvd 99
                    ll++f+d+s+sd+lv++Lr+lts ylq+es+ff++fie+++++kefcq++vep++k +++ihi+aLaq+Ls++i+v+++d
   Q: 146  VekqtsvadLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKeSDHIHIIALAQALSVSIQVEYMD 234
           15555555589****************************************************************************** PP
   S: 100  sleskvggillpllfpeeklkkpivLlYrsgHYdaLva 137
           ++e   gg+++p++fpe + +++++LlYr+gHYd+L++
   Q: 235  RGE---GGTTNPHIFPEGS-EPKVYLLYRPGHYDILYK 268
           **9...9************.****************96 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

RTSTKSTRTS ARPGLTATVS IGLSDSPTWR RCWMTARSCS GEKGGHWAPR QVGIYLLPGR 60
VGCVSSRVSP SFPGDGLDSG LARRGSAIWA LASGLVEEPM LGPPFHPTPR FKAVSAKSKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTCTCCGC AGGACCTCCA CAAAAAGTAC TCGTACATCC GCAAGACCAG GCCTGACGGC 60
AACTGTTTCT ATCGGGCTTT CGGATTCTCC CACTTGGAGG CGCTGCTGGA TGACAGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030298--OTUB1
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000780--P:negative regulation of double-strand break repair
GO:1901315--P:negative regulation of histone H2A K63-linked ubiquitination
GO:0071108--P:protein K48-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001871	Ailuropoda melanoleuca	100.00	1.00e-92	332.00
IUUC-Apl-003233	Anas platyrhynchos	58.46	2.00e-18	83.20
IUUC-Aca-004648	Anolis carolinensis	87.65	2.00e-81	295.00
IUUC-Afl-008439	Aspergillus flavus	34.18	2.00e-08	52.40
IUUC-Ame-010662	Astyanax mexicanus	83.02	7.00e-78	283.00
IUUC-Bta-013533	Bos taurus	98.11	2.00e-91	328.00
IUUC-Cja-019190	Callithrix jacchus	100.00	8.00e-93	333.00
IUUC-Cfa-020430	Canis familiaris	100.00	1.00e-92	332.00
IUUC-Cpo-022355	Cavia porcellus	99.37	4.00e-93	333.00
IUUC-Csa-023286	Chlorocebus sabaeus	100.00	4.00e-93	333.00
IUUC-Dre-027843	Danio rerio	84.91	5.00e-80	290.00
IUUC-Dno-029165	Dasypus novemcinctus	100.00	8.00e-93	332.00
IUUC-Dor-030943	Dipodomys ordii	99.37	4.00e-93	333.00
IUUC-Dme-031922	Drosophila melanogaster	58.90	2.00e-51	195.00
IUUC-Ete-032296	Echinops telfairi	79.54	2.00e-113	401.00
IUUC-Eca-033695	Equus caballus	98.11	6.00e-91	326.00
IUUC-Fca-036441	Felis catus	100.00	1.00e-92	332.00
IUUC-Gmo-038908	Gadus morhua	81.13	6.00e-76	276.00
IUUC-Ggr-040020	Gaeumannomyces graminis	33.75	2.00e-19	91.30
IUUC-Gga-040460	Gallus gallus	77.36	1.00e-73	269.00
IUUC-Gac-042417	Gasterosteus aculeatus	80.50	6.00e-76	276.00
IUUC-Hsa-046766	Homo sapiens	100.00	3.00e-93	334.00
IUUC-Itr-048312	Ictidomys tridecemlineatus	99.37	4.00e-93	333.00
IUUC-Lch-050602	Latimeria chalumnae	88.06	1.00e-67	249.00
IUUC-Laf-053705	Loxodonta africana	99.37	4.00e-93	333.00
IUUC-Mcc-055745	Macaca mulatta	100.00	3.00e-92	331.00
IUUC-Meu-056569	Macropus eugenii	97.48	2.00e-91	328.00
IUUC-Mmr-061123	Microcebus murinus	99.17	5.00e-66	244.00
IUUC-Mdo-062613	Monodelphis domestica	87.42	8.00e-65	239.00
IUUC-Mmu-063658	Mus musculus	99.37	4.00e-93	333.00
IUUC-Mpu-066172	Mustela putorius furo	100.00	3.00e-93	334.00
IUUC-Mlu-066966	Myotis lucifugus	99.37	1.00e-92	332.00
IUUC-Nle-069519	Nomascus leucogenys	93.75	1.00e-141	495.00
IUUC-Ont-071901	Oreochromis niloticus	80.50	5.00e-76	277.00
IUUC-Ola-087331	Oryzias latipes	80.50	6.00e-76	276.00
IUUC-Oga-088064	Otolemur garnettii	100.00	3.00e-93	334.00
IUUC-Oar-089251	Ovis aries	98.11	1.00e-90	325.00
IUUC-Ptr-091430	Pan troglodytes	100.00	8.00e-93	333.00
IUUC-Psi-093823	Pelodiscus sinensis	85.80	4.00e-79	287.00
IUUC-Pma-094366	Petromyzon marinus	70.90	1.00e-75	275.00
IUUC-Pfo-096734	Poecilia formosa	79.25	2.00e-74	272.00
IUUC-Pab-097919	Pongo abelii	100.00	2.00e-66	245.00
IUUC-Pva-102499	Pteropus vampyrus	100.00	4.00e-93	333.00
IUUC-Rno-105233	Rattus norvegicus	99.37	4.00e-93	333.00
IUUC-Sha-107081	Sarcophilus harrisii	98.11	4.00e-91	327.00
IUUC-Ssc-116202	Sus scrofa	100.00	3.00e-93	334.00
IUUC-Tru-117664	Takifugu rubripes	79.25	2.00e-74	272.00
IUUC-Tbe-128116	Tupaia belangeri	80.45	1.00e-117	416.00
IUUC-Ttr-128622	Tursiops truncatus	100.00	4.00e-93	334.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence