iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097919

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01159834

Gene Name

OTUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000003121.2	ENSPPYT00000003734.2	ENSPPYP00000003605.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	2.60e-34	118.7	81	232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+kt++DGnC++rA+++s                                                          ll++f+d+s+sd
   Q: 81   YIRKTRPDGNCFYRAFGFShleallddskelqrfkavsakskedlvsqgfteftiedfhntfmdlieqvekqtsvadLLASFNDQSTSD 169
           89*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpii 94
           +lv++Lr+lts ylq+es+ff++fie+++++kefcq++vep++k +++ihi+aLaq+Ls++i+
   Q: 170  YLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKeSDHIHIIALAQALSVSIQ 232
           **************************************************************8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAAEEPQQQK QEPLGSDSEG VNCLAYDEAI MAQQDRIQQE IAVQNPLVSE RLELSVLYKE 60
YAEDDNIYQQ KIKDLHKKYS YIRKTRPDGN CFYRAFGFSH LEALLDDSKE LQRFKAVSAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAAGAAA ACGGAATTGG CTCCAGGAGG ATCTGCAATC ACCATCGGGA ACTTTGGGAG 60
GCTGGGAAGA TGGAGCCAAA CCAGTGTGTG GGGTGGAGGT GCGGACCTGG GGCGGCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030298--OTUB1
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000780--P:negative regulation of double-strand break repair
GO:1901315--P:negative regulation of histone H2A K63-linked ubiquitination
GO:0071108--P:protein K48-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001871	Ailuropoda melanoleuca	97.86	6.00e-129	452.00
IUUC-Apl-003233	Anas platyrhynchos	58.46	1.00e-18	84.00
IUUC-Aca-004648	Anolis carolinensis	83.76	6.00e-111	393.00
IUUC-Aly-005710	Arabidopsis lyrata	40.34	4.00e-41	161.00
IUUC-Ath-007112	Arabidopsis thaliana	41.74	2.00e-40	159.00
IUUC-Ame-010662	Astyanax mexicanus	75.20	6.00e-107	379.00
IUUC-Bta-013533	Bos taurus	99.14	2.00e-126	444.00
IUUC-Bol-016100	Brassica oleracea	40.85	8.00e-40	157.00
IUUC-Bra-017705	Brassica rapa	37.66	1.00e-34	140.00
IUUC-Cel-018295	Caenorhabditis elegans	32.02	4.00e-30	124.00
IUUC-Cja-019190	Callithrix jacchus	100.00	2.00e-127	447.00
IUUC-Cfa-020430	Canis familiaris	100.00	3.00e-123	434.00
IUUC-Cpo-022355	Cavia porcellus	100.00	1.00e-127	449.00
IUUC-Cre-022997	Chlamydomonas reinhardtii	38.65	5.00e-37	147.00
IUUC-Csa-023286	Chlorocebus sabaeus	96.27	7.00e-125	439.00
IUUC-Cin-025507	Ciona intestinalis	43.33	2.00e-44	171.00
IUUC-Csv-026273	Ciona savignyi	43.90	9.00e-55	206.00
IUUC-Dre-027843	Danio rerio	71.04	3.00e-103	367.00
IUUC-Dno-029165	Dasypus novemcinctus	98.76	2.00e-91	328.00
IUUC-Dor-030943	Dipodomys ordii	100.00	1.00e-127	449.00
IUUC-Dme-031922	Drosophila melanogaster	48.76	2.00e-57	215.00
IUUC-Ete-032296	Echinops telfairi	95.83	4.00e-63	234.00
IUUC-Eca-033695	Equus caballus	98.59	9.00e-122	429.00
IUUC-Fca-036441	Felis catus	100.00	5.00e-123	433.00
IUUC-Gmo-038908	Gadus morhua	72.94	2.00e-104	371.00
IUUC-Ggr-040020	Gaeumannomyces graminis	30.32	2.00e-24	107.00
IUUC-Gga-040460	Gallus gallus	80.95	3.00e-109	387.00
IUUC-Gac-042417	Gasterosteus aculeatus	73.66	2.00e-100	358.00
IUUC-Gma-043712	Glycine max	41.48	2.00e-42	166.00
IUUC-Ggo-044552	Gorilla gorilla	100.00	3.00e-66	244.00
IUUC-Hsa-046766	Homo sapiens	100.00	1.00e-127	449.00
IUUC-Itr-048312	Ictidomys tridecemlineatus	100.00	1.00e-127	449.00
IUUC-Lch-050602	Latimeria chalumnae	79.72	6.00e-95	340.00
IUUC-Laf-053705	Loxodonta africana	100.00	1.00e-127	449.00
IUUC-Mcc-055745	Macaca mulatta	92.80	9.00e-124	436.00
IUUC-Meu-056569	Macropus eugenii	83.62	1.00e-108	385.00
IUUC-Mtr-057712	Medicago truncatula	43.05	2.00e-37	149.00
IUUC-Mvi-060358	Microbotryum violaceum	33.94	4.00e-15	75.50
IUUC-Mmr-061123	Microcebus murinus	99.15	4.00e-129	453.00
IUUC-Mdo-062613	Monodelphis domestica	86.57	1.00e-102	365.00
IUUC-Mmu-063658	Mus musculus	100.00	1.00e-127	449.00
IUUC-Mac-065274	Musa acuminata	37.69	8.00e-31	127.00
IUUC-Mpu-066172	Mustela putorius furo	100.00	1.00e-127	449.00
IUUC-Mlu-066966	Myotis lucifugus	99.14	8.00e-127	446.00
IUUC-Nle-069519	Nomascus leucogenys	85.03	1.00e-66	246.00
IUUC-Ont-071901	Oreochromis niloticus	75.00	1.00e-102	365.00
IUUC-Ola-087331	Oryzias latipes	70.18	1.00e-63	235.00
IUUC-Oga-088064	Otolemur garnettii	100.00	1.00e-127	449.00
IUUC-Oar-089251	Ovis aries	98.14	4.00e-121	427.00
IUUC-Ptr-091430	Pan troglodytes	100.00	4.00e-127	447.00
IUUC-Psi-093823	Pelodiscus sinensis	86.88	1.00e-108	385.00
IUUC-Pma-094366	Petromyzon marinus	63.74	2.00e-81	295.00
IUUC-Pfo-096734	Poecilia formosa	73.77	3.00e-92	331.00
IUUC-Pop-099401	Populus trichocarpa	40.97	4.00e-40	158.00
IUUC-Ppe-101977	Prunus persica	41.26	1.00e-41	163.00
IUUC-Pva-102499	Pteropus vampyrus	100.00	1.00e-122	432.00
IUUC-Rno-105233	Rattus norvegicus	100.00	1.00e-127	449.00
IUUC-Sha-107081	Sarcophilus harrisii	98.59	5.00e-122	430.00
IUUC-Sly-111640	Solanum lycopersicum	41.70	2.00e-40	159.00
IUUC-Ssc-116202	Sus scrofa	100.00	1.00e-127	449.00
IUUC-Tru-117664	Takifugu rubripes	77.73	4.00e-101	360.00
IUUC-Tca-121467	Theobroma cacao	41.33	2.00e-41	162.00
IUUC-Tbe-128116	Tupaia belangeri	100.00	2.00e-66	245.00
IUUC-Ttr-128622	Tursiops truncatus	99.14	5.00e-125	440.00
IUUC-Vvi-131389	Vitis vinifera	44.95	5.00e-44	171.00
IUUC-Xma-134191	Xiphophorus maculatus	74.18	3.00e-93	334.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence