iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID	HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/DUIM	87.90	0.00e+00	1368.00	IUUC-Hsa-046286
UBD/Alpha-Helix/UIM	92.99	0.00e+00	1419.00	IUUC-Mmu-064091
UBD/Alpha-Helix/UBA	28.08	2.00e-33	139.00	IUUC-Sce-106303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAAAAQLSLT QLSSGNPVYE KYYRQVEAGN TGRVLALDAA AFLKKSGLPD LILGKIWDLA 60
DTDGKGVLNK QEFFIALRLV ACAQNGLEVS LSSLNLAVPP PRFHDSSSPL LTSGTSVAEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCGG CAGCCCAGCT CTCCCTGACA CAGGTAACGC CGCCCGCCGG TCGGCCAGGC 60
TCGACCTGCT GGGGTTACCC CGGCCCTCCC CCCACCGCTC TGGGCGCTGG CGCGGCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR003903--UIM_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50330--UIM

Pfam

PF12763--EF-hand_4

SMART

SM00054--EFh
SM00027--EH
SM00726--UIM

Gene Ontology

GO:0016235--C:aggresome
GO:0030122--C:AP-2 adaptor complex
GO:0016324--C:apical plasma membrane
GO:0009925--C:basal plasma membrane
GO:0060170--C:ciliary membrane
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0043231--C:intracellular membrane-bounded organelle
GO:0045202--C:synapse
GO:0005509--F:calcium ion binding
GO:0048268--P:clathrin coat assembly
GO:0032456--P:endocytic recycling
GO:0006895--P:Golgi to endosome transport
GO:0001921--P:positive regulation of receptor recycling
GO:0019065--P:receptor-mediated endocytosis of virus by host cell
GO:0042127--P:regulation of cell proliferation
GO:0016185--P:synaptic vesicle budding from presynaptic endocytic zone membrane

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001596	Ailuropoda melanoleuca	86.37	0.00e+00	1313.00
IUUC-Apl-003288	Anas platyrhynchos	73.44	0.00e+00	1057.00
IUUC-Aca-005333	Anolis carolinensis	68.38	0.00e+00	1037.00
IUUC-Ago-007867	Ashbya gossypii	28.00	2.00e-30	128.00
IUUC-Ani-009469	Aspergillus nidulans	29.75	1.00e-37	152.00
IUUC-Bta-013028	Bos taurus	86.27	0.00e+00	1354.00
IUUC-Bol-015187	Brassica oleracea	38.04	9.00e-13	68.90
IUUC-Bra-017706	Brassica rapa	38.04	3.00e-12	67.80
IUUC-Cja-019821	Callithrix jacchus	86.00	0.00e+00	1389.00
IUUC-Cfa-021233	Canis familiaris	86.03	0.00e+00	1040.00
IUUC-Cpo-022339	Cavia porcellus	87.00	0.00e+00	1385.00
IUUC-Csa-024072	Chlorocebus sabaeus	86.33	0.00e+00	1338.00
IUUC-Cho-025000	Choloepus hoffmanni	69.63	0.00e+00	1037.00
IUUC-Cme-027270	Cyanidioschyzon merolae	32.41	3.00e-20	93.60
IUUC-Dre-027504	Danio rerio	59.75	4.00e-166	578.00
IUUC-Dno-029498	Dasypus novemcinctus	81.54	0.00e+00	1291.00
IUUC-Dor-030630	Dipodomys ordii	84.46	0.00e+00	1339.00
IUUC-Ete-032737	Echinops telfairi	73.09	0.00e+00	825.00
IUUC-Eca-033328	Equus caballus	87.95	0.00e+00	1369.00
IUUC-Eeu-035267	Erinaceus europaeus	77.49	0.00e+00	849.00
IUUC-Fca-035511	Felis catus	86.92	0.00e+00	1372.00
IUUC-Fal-036796	Ficedula albicollis	70.91	0.00e+00	1041.00
IUUC-Fso-038230	Fusarium solani	28.53	7.00e-38	153.00
IUUC-Gmo-038971	Gadus morhua	57.68	2.00e-163	569.00
IUUC-Gga-040315	Gallus gallus	71.09	0.00e+00	1062.00
IUUC-Gac-042011	Gasterosteus aculeatus	55.94	2.00e-151	530.00
IUUC-Ggo-045493	Gorilla gorilla	83.33	0.00e+00	1305.00
IUUC-Hsa-046286	Homo sapiens	87.90	0.00e+00	1396.00
IUUC-Loc-052749	Lepisosteus oculatus	51.02	1.00e-149	523.00
IUUC-Laf-054158	Loxodonta africana	85.30	0.00e+00	1337.00
IUUC-Mcc-055325	Macaca mulatta	87.80	0.00e+00	1380.00
IUUC-Mtr-058311	Medicago truncatula	34.09	5.00e-14	73.90
IUUC-Mga-060058	Meleagris gallopavo	70.24	0.00e+00	1088.00
IUUC-Mmr-061060	Microcebus murinus	87.70	0.00e+00	1375.00
IUUC-Mmu-064091	Mus musculus	92.99	0.00e+00	1325.00
IUUC-Mac-065649	Musa acuminata	22.73	8.00e-11	63.20
IUUC-Mpu-065932	Mustela putorius furo	86.04	0.00e+00	1349.00
IUUC-Mlu-067488	Myotis lucifugus	85.59	0.00e+00	1344.00
IUUC-Nle-068996	Nomascus leucogenys	88.01	0.00e+00	1381.00
IUUC-Ont-071424	Oreochromis niloticus	54.86	0.00e+00	639.00
IUUC-Oan-073457	Ornithorhynchus anatinus	64.44	0.00e+00	706.00
IUUC-Ocu-074535	Oryctolagus cuniculus	87.26	0.00e+00	1356.00
IUUC-Ola-087107	Oryzias latipes	55.77	2.00e-144	506.00
IUUC-Oga-088532	Otolemur garnettii	85.56	0.00e+00	1343.00
IUUC-Oar-089833	Ovis aries	86.31	0.00e+00	1376.00
IUUC-Ptr-090733	Pan troglodytes	87.90	0.00e+00	1384.00
IUUC-Pan-092491	Papio anubis	83.28	0.00e+00	1249.00
IUUC-Psi-094063	Pelodiscus sinensis	72.94	0.00e+00	1093.00
IUUC-Pma-094451	Petromyzon marinus	55.16	2.00e-97	348.00
IUUC-Ppa-095176	Physcomitrella patens	34.74	1.00e-13	72.40
IUUC-Pab-098749	Pongo abelii	88.08	0.00e+00	1404.00
IUUC-Pca-100378	Procavia capensis	72.19	0.00e+00	825.00
IUUC-Ppe-102036	Prunus persica	35.16	1.00e-11	65.90
IUUC-Pva-102739	Pteropus vampyrus	85.79	0.00e+00	1209.00
IUUC-Sce-106303	Saccharomyces cerevisiae	28.08	2.00e-33	138.00
IUUC-Smo-109013	Selaginella moellendorffii	40.22	6.00e-16	75.10
IUUC-Sly-111403	Solanum lycopersicum	33.33	2.00e-12	68.20
IUUC-Stu-112258	Solanum tuberosum	34.57	1.00e-08	55.10
IUUC-Sar-113358	Sorex araneus	68.41	0.00e+00	860.00
IUUC-Ssc-115746	Sus scrofa	85.24	0.00e+00	1340.00
IUUC-Tgu-117351	Taeniopygia guttata	71.01	0.00e+00	1042.00
IUUC-Tru-117870	Takifugu rubripes	55.15	0.00e+00	702.00
IUUC-Tsy-118873	Tarsius syrichta	77.74	0.00e+00	853.00
IUUC-Tni-120351	Tetraodon nigroviridis	54.57	0.00e+00	695.00
IUUC-Tca-121631	Theobroma cacao	43.94	1.00e-11	65.50
IUUC-Tbe-127307	Tupaia belangeri	85.15	0.00e+00	1282.00
IUUC-Ttr-128775	Tursiops truncatus	83.50	0.00e+00	1250.00
IUUC-Vpa-130684	Vicugna pacos	81.26	0.00e+00	1295.00
IUUC-Xtr-132716	Xenopus tropicalis	56.31	0.00e+00	833.00
IUUC-Xma-133907	Xiphophorus maculatus	51.11	2.00e-179	622.00
IUUC-Yli-134577	Yarrowia lipolytica	28.41	2.00e-36	148.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence