iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106529

Ensembl Protein ID

ENSSHAP00000012468.1

UniProt Accession

G3WAL3; G3WAL3_SARHA

Genbank Protein ID

ENSSHAP00000012468

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01022722

Gene Name

VAV2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010676.1	ENSSHAT00000012570.1	ENSSHAP00000012468.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-18	66.1	644	695

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 644  ARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKG--ETNGRIGWFPSTYVEE 695
           67**********************************..9*************86 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

QPKIRYMQKM GMTEDDKRNC CLLEIQETEA KYYRTLEDIE KNYMNPLKLV LSPLDMTAIF 60
INLEDLIKVH NSFLRAIDVS MMAGGSSLAK VFLEFKERLL IYGEYCSHME YAQNTLNHLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCCAAGG TAAAAGCTTA GGGAATAACA AATCATCCCT TTTCTTTGAA GTCAGGGTAT 60
GAGGAAGTCT TCTGTGGCCA CACTCGGTTC CAGAATTGGA GCCATGATGT GTGTGCATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	91.42	0.00e+00	1236.00
IUUC-Apl-003262	Anas platyrhynchos	92.04	0.00e+00	1240.00
IUUC-Aca-004628	Anolis carolinensis	65.72	0.00e+00	823.00
IUUC-Ath-007352	Arabidopsis thaliana	38.36	2.00e-04	40.80
IUUC-Ame-011608	Astyanax mexicanus	78.95	0.00e+00	1143.00
IUUC-Bta-013147	Bos taurus	92.63	0.00e+00	1281.00
IUUC-Cja-018877	Callithrix jacchus	89.27	0.00e+00	1199.00
IUUC-Cfa-020315	Canis familiaris	89.00	0.00e+00	1223.00
IUUC-Cpo-021543	Cavia porcellus	90.17	0.00e+00	1224.00
IUUC-Csa-024204	Chlorocebus sabaeus	90.79	0.00e+00	1269.00
IUUC-Dre-028308	Danio rerio	81.51	0.00e+00	1172.00
IUUC-Dno-029584	Dasypus novemcinctus	85.08	0.00e+00	1124.00
IUUC-Dor-031014	Dipodomys ordii	78.17	0.00e+00	1011.00
IUUC-Eca-033448	Equus caballus	89.70	0.00e+00	1240.00
IUUC-Eeu-035182	Erinaceus europaeus	83.76	2.00e-130	459.00
IUUC-Fca-035460	Felis catus	90.45	0.00e+00	1221.00
IUUC-Fal-036684	Ficedula albicollis	91.02	0.00e+00	1265.00
IUUC-Gmo-038816	Gadus morhua	75.29	0.00e+00	1043.00
IUUC-Gga-040999	Gallus gallus	88.57	0.00e+00	1204.00
IUUC-Gac-041353	Gasterosteus aculeatus	77.00	0.00e+00	1077.00
IUUC-Ggo-044558	Gorilla gorilla	93.42	0.00e+00	1287.00
IUUC-Hsa-046208	Homo sapiens	93.28	0.00e+00	1285.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	88.13	0.00e+00	1191.00
IUUC-Loc-052827	Lepisosteus oculatus	83.05	0.00e+00	1212.00
IUUC-Laf-054009	Loxodonta africana	87.43	0.00e+00	1189.00
IUUC-Mcc-055054	Macaca mulatta	93.13	0.00e+00	1283.00
IUUC-Meu-056269	Macropus eugenii	88.57	0.00e+00	783.00
IUUC-Mga-060106	Meleagris gallopavo	92.33	0.00e+00	1245.00
IUUC-Mmr-061118	Microcebus murinus	90.45	0.00e+00	1228.00
IUUC-Mdo-062380	Monodelphis domestica	92.62	0.00e+00	1279.00
IUUC-Mmu-063135	Mus musculus	92.47	0.00e+00	1269.00
IUUC-Mpu-066135	Mustela putorius furo	87.23	0.00e+00	1216.00
IUUC-Nle-069465	Nomascus leucogenys	86.93	0.00e+00	1145.00
IUUC-Ont-071945	Oreochromis niloticus	80.14	0.00e+00	1125.00
IUUC-Oan-073384	Ornithorhynchus anatinus	90.32	0.00e+00	1208.00
IUUC-Ola-087499	Oryzias latipes	76.76	0.00e+00	1064.00
IUUC-Oga-088444	Otolemur garnettii	88.71	0.00e+00	1198.00
IUUC-Oar-089576	Ovis aries	87.57	0.00e+00	1181.00
IUUC-Ptr-090507	Pan troglodytes	92.62	0.00e+00	1247.00
IUUC-Pan-092325	Papio anubis	89.00	0.00e+00	1198.00
IUUC-Psi-094021	Pelodiscus sinensis	88.99	0.00e+00	1202.00
IUUC-Pma-094372	Petromyzon marinus	53.01	0.00e+00	719.00
IUUC-Pfo-096732	Poecilia formosa	81.51	0.00e+00	1161.00
IUUC-Pab-098426	Pongo abelii	75.61	0.00e+00	971.00
IUUC-Pca-100295	Procavia capensis	90.62	0.00e+00	1262.00
IUUC-Rno-105332	Rattus norvegicus	91.32	0.00e+00	1193.00
IUUC-Ssc-116176	Sus scrofa	91.22	0.00e+00	1235.00
IUUC-Tgu-116917	Taeniopygia guttata	91.61	0.00e+00	1231.00
IUUC-Tru-118398	Takifugu rubripes	79.81	0.00e+00	1013.00
IUUC-Tni-120819	Tetraodon nigroviridis	79.37	0.00e+00	1129.00
IUUC-Xtr-132747	Xenopus tropicalis	77.31	0.00e+00	1042.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence