iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000016985.3	ENSMMUT00000058366.1	ENSMMUP00000053234.1
ENSMMUG00000016985.3	ENSMMUT00000023867.3	ENSMMUP00000022340.3
ENSMMUG00000016985.3	ENSMMUT00000060951.1	ENSMMUP00000056951.1
ENSMMUG00000016985.3	ENSMMUT00000066898.1	ENSMMUP00000048227.1
ENSMMUG00000016985.3	ENSMMUT00000023869.2	ENSMMUP00000022342.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.60e-09	38.9	199	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 199  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 246
           69*.*******99..********999***********...899996.******97 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM SSARSLSSEE 60
KLALLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCGGAGC TTGCAGTGAG CTGAGATCCG GCCACTGCAC TCCAGCCTGG GCGACAGAGC 60
GAGACTCCGT CTCAAAAAAA AAAAAAAAAA AAAAAAAAAA AAGAAGTAAT ATTTTATATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	97.21	3.00e-124	437.00
IUUC-Apl-004097	Anas platyrhynchos	88.00	1.00e-117	415.00
IUUC-Aca-004593	Anolis carolinensis	89.64	2.00e-123	434.00
IUUC-Ame-011133	Astyanax mexicanus	81.75	7.00e-116	409.00
IUUC-Bta-012699	Bos taurus	96.02	5.00e-124	436.00
IUUC-Bdi-014504	Brachypodium distachyon	35.97	2.00e-39	155.00
IUUC-Bol-015245	Brassica oleracea	31.35	5.00e-30	124.00
IUUC-Bra-017027	Brassica rapa	31.75	1.00e-30	126.00
IUUC-Cja-019988	Callithrix jacchus	96.02	9.00e-120	422.00
IUUC-Cfa-021282	Canis familiaris	95.22	1.00e-118	419.00
IUUC-Cpo-022011	Cavia porcellus	95.22	6.00e-129	452.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	31.37	1.00e-29	123.00
IUUC-Csa-023203	Chlorocebus sabaeus	96.02	9.00e-120	422.00
IUUC-Cin-025479	Ciona intestinalis	60.83	3.00e-79	287.00
IUUC-Csv-026288	Ciona savignyi	55.43	3.00e-75	274.00
IUUC-Dre-028264	Danio rerio	81.35	3.00e-114	404.00
IUUC-Dno-029766	Dasypus novemcinctus	92.80	3.00e-112	397.00
IUUC-Dor-031136	Dipodomys ordii	80.67	3.00e-97	347.00
IUUC-Dme-032200	Drosophila melanogaster	84.00	2.00e-40	159.00
IUUC-Eca-033565	Equus caballus	95.22	8.00e-129	452.00
IUUC-Eeu-034948	Erinaceus europaeus	79.92	2.00e-98	352.00
IUUC-Fca-036368	Felis catus	95.62	3.00e-119	420.00
IUUC-Fal-037120	Ficedula albicollis	89.60	2.00e-116	410.00
IUUC-Gmo-038982	Gadus morhua	80.95	4.00e-114	403.00
IUUC-Gga-040771	Gallus gallus	89.64	2.00e-123	434.00
IUUC-Gac-042184	Gasterosteus aculeatus	79.84	5.00e-110	390.00
IUUC-Gma-044339	Glycine max	29.13	2.00e-33	135.00
IUUC-Ggo-045559	Gorilla gorilla	96.02	9.00e-120	422.00
IUUC-Hsa-046852	Homo sapiens	96.02	9.00e-120	422.00
IUUC-Hvu-047046	Hordeum vulgare	35.04	3.00e-37	148.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	94.82	1.00e-128	451.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.70
IUUC-Lpe-050822	Leersia perrieri	35.57	9.00e-38	150.00
IUUC-Laf-054057	Loxodonta africana	95.62	3.00e-119	420.00
IUUC-Meu-056511	Macropus eugenii	90.76	1.00e-119	422.00
IUUC-Mga-059967	Meleagris gallopavo	91.16	4.00e-117	413.00
IUUC-Mmr-060843	Microcebus murinus	96.02	2.00e-124	437.00
IUUC-Mdo-062357	Monodelphis domestica	94.82	2.00e-128	451.00
IUUC-Mmu-064093	Mus musculus	95.22	6.00e-129	452.00
IUUC-Mac-064625	Musa acuminata	34.48	6.00e-36	144.00
IUUC-Mpu-066923	Mustela putorius furo	84.46	4.00e-96	343.00
IUUC-Mlu-067754	Myotis lucifugus	86.22	7.00e-117	412.00
IUUC-Nle-069062	Nomascus leucogenys	96.02	9.00e-120	422.00
IUUC-Opr-070207	Ochotona princeps	88.66	5.00e-110	390.00
IUUC-Ont-072446	Oreochromis niloticus	80.95	2.00e-112	397.00
IUUC-Ocu-074235	Oryctolagus cuniculus	95.22	1.00e-118	419.00
IUUC-Obr-076266	Oryza brachyantha	35.97	4.00e-37	147.00
IUUC-Ogl-077118	Oryza glaberrima	34.65	9.00e-37	146.00
IUUC-Oin-079049	Oryza indica	33.46	1.00e-36	146.00
IUUC-Ome-081291	Oryza meridionalis	33.46	6.00e-36	144.00
IUUC-Oni-082218	Oryza nivara	33.46	1.00e-36	146.00
IUUC-Opu-084171	Oryza punctata	33.86	2.00e-36	146.00
IUUC-Osa-085563	Oryza sativa	33.46	6.00e-36	144.00
IUUC-Ola-086429	Oryzias latipes	76.19	1.00e-103	368.00
IUUC-Olu-087851	Ostreococcus lucimarinus	35.98	2.00e-20	92.40
IUUC-Oga-089123	Otolemur garnettii	95.62	3.00e-119	420.00
IUUC-Oar-089524	Ovis aries	96.02	5.00e-124	436.00
IUUC-Ptr-090908	Pan troglodytes	95.62	3.00e-119	420.00
IUUC-Pan-092837	Papio anubis	97.61	8.00e-125	439.00
IUUC-Psi-093828	Pelodiscus sinensis	92.34	2.00e-112	397.00
IUUC-Ppa-096009	Physcomitrella patens	33.98	4.00e-34	138.00
IUUC-Pfo-096617	Poecilia formosa	80.56	2.00e-112	398.00
IUUC-Pab-097978	Pongo abelii	95.80	6.00e-109	386.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	62.95	1.00e-83	302.00
IUUC-Ppe-101441	Prunus persica	32.56	3.00e-36	145.00
IUUC-Pva-102325	Pteropus vampyrus	95.22	8.00e-129	452.00
IUUC-Rno-105178	Rattus norvegicus	95.62	3.00e-134	470.00
IUUC-Sha-106773	Sarcophilus harrisii	95.22	2.00e-128	451.00
IUUC-Smo-109441	Selaginella moellendorffii	31.78	1.00e-39	155.00
IUUC-Sit-109827	Setaria italica	35.57	3.00e-36	144.00
IUUC-Sbi-114826	Sorghum bicolor	34.78	4.00e-37	147.00
IUUC-Sre-115124	Sporisorium reilianum	58.21	2.00e-22	100.00
IUUC-Ssc-115797	Sus scrofa	89.11	2.00e-103	367.00
IUUC-Tgu-117270	Taeniopygia guttata	89.64	2.00e-123	434.00
IUUC-Tru-118253	Takifugu rubripes	79.84	1.00e-112	399.00
IUUC-Tae-123043	Triticum aestivum	35.41	8.00e-38	150.00
IUUC-Tbe-127558	Tupaia belangeri	97.21	3.00e-124	437.00
IUUC-Ttr-128300	Tursiops truncatus	99.09	4.00e-65	241.00
IUUC-Uma-129581	Ustilago maydis	57.63	3.00e-21	97.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence