iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093828

Ensembl Protein ID

ENSPSIP00000017141.1

UniProt Accession

K7GA30; K7GA30_PELSI

Genbank Protein ID

ENSPSIP00000017141

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AGCU01093959

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000015200.1	ENSPSIT00000017219.1	ENSPSIP00000017141.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.40e-10	39.1	182	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 182  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 229
           69*.*******99..********999***********...899996.******97 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

XLPFELQRNF QLMRDLDQRT EDLKSEIDKL ATEYISNART LSSEEKLGLL KQIQEAYGKC 60
KEFGDDKVQL AMQTYEMVDK HIRRLDTDLA RFEADLKEKQ IESSDYDSSS SKGKKKGRAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NACCTGCCGT TTGAATTGCA GAGAAATTTC CAACTCATGC GAGATCTGGA CCAGCGAACA 60
GAAGGTGAGT GTCAAGAATG AGGCCCGAAG TAATCTGCTT GCGTAGATGG GGAGCCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	95.28	4.00e-113	400.00
IUUC-Atr-002906	Amborella trichopoda	33.61	8.00e-32	129.00
IUUC-Apl-004097	Anas platyrhynchos	99.57	1.00e-117	415.00
IUUC-Aca-004593	Anolis carolinensis	99.57	1.00e-117	414.00
IUUC-Ame-011133	Astyanax mexicanus	82.13	9.00e-108	382.00
IUUC-Bta-012699	Bos taurus	93.99	5.00e-113	399.00
IUUC-Bdi-014504	Brachypodium distachyon	35.83	4.00e-37	147.00
IUUC-Bol-015245	Brassica oleracea	32.77	3.00e-30	124.00
IUUC-Bra-017027	Brassica rapa	33.19	7.00e-31	126.00
IUUC-Cja-019988	Callithrix jacchus	96.14	5.00e-108	383.00
IUUC-Cfa-021282	Canis familiaris	95.71	2.00e-107	381.00
IUUC-Cpo-022011	Cavia porcellus	95.71	9.00e-117	412.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	34.29	2.00e-28	119.00
IUUC-Csa-023203	Chlorocebus sabaeus	96.14	5.00e-108	383.00
IUUC-Cin-025479	Ciona intestinalis	60.36	4.00e-71	260.00
IUUC-Csv-026288	Ciona savignyi	54.18	2.00e-67	248.00
IUUC-Dre-028264	Danio rerio	81.70	3.00e-106	377.00
IUUC-Dno-029766	Dasypus novemcinctus	96.14	8.00e-108	382.00
IUUC-Dor-031136	Dipodomys ordii	91.46	3.00e-91	327.00
IUUC-Eca-033565	Equus caballus	96.14	6.00e-117	412.00
IUUC-Eeu-034948	Erinaceus europaeus	77.25	8.00e-92	329.00
IUUC-Fca-036368	Felis catus	96.14	5.00e-108	383.00
IUUC-Fal-037120	Ficedula albicollis	99.57	2.00e-117	414.00
IUUC-Gmo-038982	Gadus morhua	81.20	2.00e-106	377.00
IUUC-Gga-040771	Gallus gallus	99.57	1.00e-117	414.00
IUUC-Gac-042184	Gasterosteus aculeatus	80.77	5.00e-105	373.00
IUUC-Gma-044339	Glycine max	29.88	8.00e-32	129.00
IUUC-Ggo-045559	Gorilla gorilla	96.14	5.00e-108	383.00
IUUC-Hsa-046852	Homo sapiens	96.14	5.00e-108	383.00
IUUC-Hvu-047046	Hordeum vulgare	36.10	5.00e-36	144.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	95.71	1.00e-116	411.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.30
IUUC-Lpe-050822	Leersia perrieri	34.58	1.00e-36	146.00
IUUC-Laf-054057	Loxodonta africana	96.14	5.00e-108	383.00
IUUC-Mcc-055212	Macaca mulatta	89.79	4.00e-102	363.00
IUUC-Meu-056511	Macropus eugenii	95.00	2.00e-107	381.00
IUUC-Mga-059967	Meleagris gallopavo	99.57	1.00e-117	415.00
IUUC-Mmr-060843	Microcebus murinus	93.99	3.00e-113	400.00
IUUC-Mdo-062357	Monodelphis domestica	95.28	3.00e-116	410.00
IUUC-Mmu-064093	Mus musculus	95.71	9.00e-117	412.00
IUUC-Mac-064625	Musa acuminata	32.92	3.00e-33	134.00
IUUC-Mpu-066923	Mustela putorius furo	83.69	5.00e-85	306.00
IUUC-Mlu-067754	Myotis lucifugus	88.56	6.00e-105	373.00
IUUC-Nle-069062	Nomascus leucogenys	96.14	5.00e-108	383.00
IUUC-Opr-070207	Ochotona princeps	89.70	6.00e-107	379.00
IUUC-Ont-072446	Oreochromis niloticus	81.62	4.00e-105	373.00
IUUC-Ocu-074235	Oryctolagus cuniculus	95.71	2.00e-107	381.00
IUUC-Obr-076266	Oryza brachyantha	34.58	2.00e-35	142.00
IUUC-Ogl-077118	Oryza glaberrima	33.61	2.00e-34	138.00
IUUC-Oin-079049	Oryza indica	34.54	7.00e-34	136.00
IUUC-Ome-081291	Oryza meridionalis	34.02	5.00e-35	140.00
IUUC-Oni-082218	Oryza nivara	34.54	7.00e-34	136.00
IUUC-Opu-084171	Oryza punctata	34.43	4.00e-35	141.00
IUUC-Osa-085563	Oryza sativa	34.02	5.00e-35	140.00
IUUC-Ola-086429	Oryzias latipes	76.50	4.00e-96	343.00
IUUC-Oga-089123	Otolemur garnettii	96.14	5.00e-108	383.00
IUUC-Oar-089524	Ovis aries	93.99	5.00e-113	399.00
IUUC-Ptr-090908	Pan troglodytes	95.71	2.00e-107	381.00
IUUC-Pan-092837	Papio anubis	95.28	4.00e-113	400.00
IUUC-Ppa-096009	Physcomitrella patens	34.01	1.00e-29	122.00
IUUC-Pfo-096617	Poecilia formosa	81.20	3.00e-105	374.00
IUUC-Pab-097978	Pongo abelii	95.71	1.00e-105	375.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	62.23	6.00e-73	266.00
IUUC-Ppe-101441	Prunus persica	33.47	2.00e-34	139.00
IUUC-Pva-102325	Pteropus vampyrus	96.14	6.00e-117	412.00
IUUC-Rno-105178	Rattus norvegicus	93.99	6.00e-122	429.00
IUUC-Sha-106773	Sarcophilus harrisii	95.28	5.00e-116	410.00
IUUC-Sit-109827	Setaria italica	34.58	4.00e-34	137.00
IUUC-Sly-111750	Solanum lycopersicum	34.58	8.00e-35	139.00
IUUC-Stu-112250	Solanum tuberosum	34.58	8.00e-35	139.00
IUUC-Sbi-114826	Sorghum bicolor	33.75	2.00e-35	142.00
IUUC-Sre-115124	Sporisorium reilianum	51.85	1.00e-22	101.00
IUUC-Ssc-115797	Sus scrofa	93.13	5.00e-101	359.00
IUUC-Tgu-117270	Taeniopygia guttata	99.57	1.00e-117	414.00
IUUC-Tru-118253	Takifugu rubripes	80.43	3.00e-105	374.00
IUUC-Tae-123043	Triticum aestivum	35.92	4.00e-35	141.00
IUUC-Tbe-127558	Tupaia belangeri	95.28	4.00e-113	400.00
IUUC-Ttr-128300	Tursiops truncatus	97.27	1.00e-63	236.00
IUUC-Uma-129581	Ustilago maydis	57.63	3.00e-21	96.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence