iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090955

Ensembl Protein ID

ENSPTRP00000006703.2

UniProt Accession

H2Q439; H2Q439_PANTR

Genbank Protein ID

JAA09220.1; JAA13788.1; JAA30369.1; JAA43855.1

Protein Name

Mitogen-activated protein kinase kinase kinase 11

Genbank Nucleotide ID

AACZ03082532; GABF01008357; GABD01002731; GABE01000884

Gene Name

MAP3K11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000003886.2	ENSPTRT00000007266.2	ENSPTRP00000006703.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.20e-15	54.9	47	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvkelegkrGlfPenFvek 61
            +l+dye++ +deL l+kGd v+v+      + degW+ g  +  g+ G+fP+n+v +
   Q: 47   TALFDYEPSGQDELALRKGDRVEVLsrdAAISGDEGWWAG--QVGGQVGIFPSNYVSR 102
           69***********************66555689*******..7************975 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEPLKSLFLK SPLGSWNGSG SGGGGGGGGG QPEGSPKAAG YANPVWTALF DYEPSGQDEL 60
ALRKGDRVEV LSRDAAISGD EGWWAGQVGG QVGIFPSNYV SRGGGPPPCE VASFQELRLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAAAGGGAG GAGGAAGAAG GGAGCGGGGT CGGAGCCGTC GGGGCCAAAG TAGACGGGGC 60
CAGGAACAGG CAGTCTCGGC CCAACTGCGG ACGCTCCCTC CACCCCCTGC GCAAAAAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0005874--C:microtubule
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0007257--P:activation of JUN kinase activity
GO:0008283--P:cell proliferation
GO:0007017--P:microtubule-based process
GO:0043065--P:positive regulation of apoptotic process
GO:0046777--P:protein autophosphorylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002080	Ailuropoda melanoleuca	93.60	0.00e+00	1041.00
IUUC-Ame-011785	Astyanax mexicanus	70.00	0.00e+00	709.00
IUUC-Bta-012372	Bos taurus	92.36	0.00e+00	1130.00
IUUC-Bol-015857	Brassica oleracea	32.84	6.00e-27	115.00
IUUC-Cja-019543	Callithrix jacchus	93.27	0.00e+00	1144.00
IUUC-Cfa-020080	Canis familiaris	97.55	0.00e+00	1006.00
IUUC-Cpo-022478	Cavia porcellus	92.82	0.00e+00	1167.00
IUUC-Csa-023280	Chlorocebus sabaeus	99.49	0.00e+00	1013.00
IUUC-Dno-030074	Dasypus novemcinctus	90.78	0.00e+00	1247.00
IUUC-Dor-030866	Dipodomys ordii	94.58	0.00e+00	1185.00
IUUC-Eca-033782	Equus caballus	97.26	4.00e-172	598.00
IUUC-Fca-035440	Felis catus	90.62	0.00e+00	1148.00
IUUC-Gac-042299	Gasterosteus aculeatus	61.99	0.00e+00	703.00
IUUC-Ggo-044795	Gorilla gorilla	99.76	0.00e+00	1270.00
IUUC-Hsa-046270	Homo sapiens	99.41	0.00e+00	1292.00
IUUC-Itr-048561	Ictidomys tridecemlineatus	95.05	0.00e+00	1162.00
IUUC-Lch-049724	Latimeria chalumnae	63.32	0.00e+00	698.00
IUUC-Meu-056762	Macropus eugenii	90.58	0.00e+00	751.00
IUUC-Mdo-062929	Monodelphis domestica	83.27	0.00e+00	1159.00
IUUC-Mmu-063196	Mus musculus	94.36	0.00e+00	1190.00
IUUC-Mpu-066569	Mustela putorius furo	91.43	0.00e+00	1201.00
IUUC-Mlu-067815	Myotis lucifugus	93.01	0.00e+00	1144.00
IUUC-Ont-071274	Oreochromis niloticus	72.92	0.00e+00	714.00
IUUC-Ocu-074842	Oryctolagus cuniculus	93.03	0.00e+00	1192.00
IUUC-Olo-080520	Oryza longistaminata	31.79	1.00e-22	101.00
IUUC-Ome-081788	Oryza meridionalis	30.15	8.00e-31	128.00
IUUC-Oga-088038	Otolemur garnettii	95.51	0.00e+00	1204.00
IUUC-Oar-089467	Ovis aries	91.55	0.00e+00	1114.00
IUUC-Pan-091695	Papio anubis	98.82	0.00e+00	1282.00
IUUC-Psi-093760	Pelodiscus sinensis	68.04	0.00e+00	912.00
IUUC-Pfo-096248	Poecilia formosa	58.80	0.00e+00	700.00
IUUC-Pab-097966	Pongo abelii	99.76	0.00e+00	1300.00
IUUC-Pca-100802	Procavia capensis	98.90	5.00e-101	362.00
IUUC-Pva-102546	Pteropus vampyrus	94.12	0.00e+00	1161.00
IUUC-Rno-104963	Rattus norvegicus	93.65	0.00e+00	1255.00
IUUC-Sha-107470	Sarcophilus harrisii	79.05	0.00e+00	1080.00
IUUC-Tni-120577	Tetraodon nigroviridis	61.09	0.00e+00	707.00
IUUC-Ttr-129146	Tursiops truncatus	93.47	0.00e+00	1077.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence