iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004251

Ensembl Protein ID

ENSACAP00000015756.2

UniProt Accession

G1KRZ9; G1KRZ9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015928.2	ENSACAT00000016072.2	ENSACAP00000015756.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-16	60.5	426	482

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k G+ ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 426  RVRALYDYEGQEHDELSFKTGEELTKI-EDEDEQGWCKG-RLDNGQVGLYPANYVEPIQ 482
           799************************.9**********.59*************9985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

KALTYSEHYT IILSIPKAFE VGNYKRTVKR IDDGYRLCSD LMNCIHERAR IEKGYAQQLT 60
EWAKRWKQLV EKGPQYGTVE KAWHAFMSEA EKVSELHLEV KGALMNEDFE KIKNWQKDSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGCACTGA CTTATTCTGA GCATTACACC ATTATTTTGA GTATCCCAAG GGAGATATTT 60
GCGTGCTCTA AACAGAAGAA ACCAACTGAG GAACCTTCGA CAACACATTG AGGAATAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	85.47	0.00e+00	771.00
IUUC-Apl-003574	Anas platyrhynchos	90.79	0.00e+00	790.00
IUUC-Ame-011756	Astyanax mexicanus	65.03	0.00e+00	644.00
IUUC-Bta-013193	Bos taurus	81.24	0.00e+00	731.00
IUUC-Cel-018168	Caenorhabditis elegans	30.21	2.00e-56	213.00
IUUC-Cja-018756	Callithrix jacchus	81.24	0.00e+00	723.00
IUUC-Cfa-020545	Canis familiaris	83.51	0.00e+00	781.00
IUUC-Cpo-022000	Cavia porcellus	79.38	0.00e+00	793.00
IUUC-Csa-024030	Chlorocebus sabaeus	82.70	0.00e+00	672.00
IUUC-Csv-026244	Ciona savignyi	43.56	7.00e-53	199.00
IUUC-Dre-028104	Danio rerio	61.79	4.00e-159	554.00
IUUC-Dno-029429	Dasypus novemcinctus	82.82	0.00e+00	733.00
IUUC-Dor-030122	Dipodomys ordii	76.49	0.00e+00	697.00
IUUC-Dme-032120	Drosophila melanogaster	43.93	9.00e-101	360.00
IUUC-Eca-033367	Equus caballus	81.57	0.00e+00	756.00
IUUC-Eeu-034821	Erinaceus europaeus	66.39	5.00e-170	590.00
IUUC-Fca-036079	Felis catus	85.90	0.00e+00	777.00
IUUC-Fal-036682	Ficedula albicollis	90.58	0.00e+00	789.00
IUUC-Gmo-039681	Gadus morhua	63.69	1.00e-149	522.00
IUUC-Gga-040717	Gallus gallus	90.58	0.00e+00	786.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.84	2.00e-169	588.00
IUUC-Gma-044347	Glycine max	25.64	2.10e+00	26.20
IUUC-Ggo-044841	Gorilla gorilla	81.24	0.00e+00	721.00
IUUC-Hsa-046411	Homo sapiens	81.24	0.00e+00	720.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	84.40	0.00e+00	734.00
IUUC-Loc-051975	Lepisosteus oculatus	69.83	0.00e+00	666.00
IUUC-Laf-053839	Loxodonta africana	82.28	0.00e+00	767.00
IUUC-Mcc-055783	Macaca mulatta	80.82	0.00e+00	718.00
IUUC-Mga-060087	Meleagris gallopavo	84.37	0.00e+00	707.00
IUUC-Mvi-060548	Microbotryum violaceum	41.38	3.00e-07	51.20
IUUC-Mmr-060827	Microcebus murinus	82.06	0.00e+00	755.00
IUUC-Mmu-064109	Mus musculus	82.06	0.00e+00	756.00
IUUC-Mpu-066591	Mustela putorius furo	86.11	0.00e+00	776.00
IUUC-Mlu-067826	Myotis lucifugus	83.30	0.00e+00	775.00
IUUC-Nle-069797	Nomascus leucogenys	81.24	0.00e+00	720.00
IUUC-Oan-073076	Ornithorhynchus anatinus	80.17	8.00e-147	512.00
IUUC-Ocu-074425	Oryctolagus cuniculus	86.27	0.00e+00	746.00
IUUC-Ola-087556	Oryzias latipes	64.07	4.00e-157	547.00
IUUC-Oga-089009	Otolemur garnettii	79.48	0.00e+00	726.00
IUUC-Oar-089806	Ovis aries	81.24	0.00e+00	731.00
IUUC-Ptr-091111	Pan troglodytes	81.24	0.00e+00	719.00
IUUC-Pan-091749	Papio anubis	83.05	0.00e+00	713.00
IUUC-Psi-093704	Pelodiscus sinensis	90.36	0.00e+00	793.00
IUUC-Pfo-096680	Poecilia formosa	64.78	5.00e-165	573.00
IUUC-Pva-102649	Pteropus vampyrus	81.86	0.00e+00	733.00
IUUC-Pgr-103636	Puccinia graminis	43.64	2.00e-10	58.50
IUUC-Rno-105431	Rattus norvegicus	82.34	0.00e+00	790.00
IUUC-Sha-106641	Sarcophilus harrisii	87.12	0.00e+00	773.00
IUUC-Sar-113461	Sorex araneus	75.64	0.00e+00	663.00
IUUC-Ssc-115349	Sus scrofa	84.80	0.00e+00	734.00
IUUC-Tgu-116876	Taeniopygia guttata	90.36	0.00e+00	784.00
IUUC-Tru-118306	Takifugu rubripes	66.87	3.00e-169	587.00
IUUC-Tsy-118901	Tarsius syrichta	75.52	7.00e-136	477.00
IUUC-Tni-120120	Tetraodon nigroviridis	67.59	6.00e-173	600.00
IUUC-Xtr-132925	Xenopus tropicalis	80.42	0.00e+00	751.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence