iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092686

Ensembl Protein ID

ENSPANP00000011663.1

UniProt Accession

A0A096NFG7; A0A096NFG7_PAPAN

Genbank Protein ID

ENSPANP00000011663

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01032073

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000014344.1	ENSPANT00000020002.1	ENSPANP00000011663.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.50e-99	331.2	268	597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l+++  ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 268  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLHHS--SNAHTALMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 354
           9*****************************7788888877..6799***************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+  l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 355  QQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDH--LPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 441
           *******************9944444444444442..2222335559****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 442  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 527
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 528  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpGTGEWHTFNDSSVTPMSSSQVRT---SDAYLLFYE 597
           ******9553....78*************************44555*******************...********8 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDA HYSKSGYGAY TPSSYGANLA ASLLEKEKFG FKPVPASSFL 60
TRPRTYGPSS ILDYDRGRPL LRPDITGGGK RAESQTRGTE RPSGSGLSGG SGFPYGVSNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATGAGGC TCCCAGTTCC CACTGAGTGC GACCCTGAAG GATGTCCCAG CTCTCCTCCA 60
CCCTGAAGCG CTACACAGAA TCAGCCCGCT ACACAGATGC CCACTATTCC AAGTCGGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	92.74	0.00e+00	1073.00
IUUC-Aca-005132	Anolis carolinensis	60.39	0.00e+00	672.00
IUUC-Ame-011102	Astyanax mexicanus	74.93	5.00e-145	507.00
IUUC-Bta-012529	Bos taurus	90.59	0.00e+00	1008.00
IUUC-Cja-019016	Callithrix jacchus	93.28	0.00e+00	1080.00
IUUC-Cfa-020714	Canis familiaris	92.90	0.00e+00	1102.00
IUUC-Cpo-021727	Cavia porcellus	88.45	0.00e+00	1011.00
IUUC-Csa-023071	Chlorocebus sabaeus	100.00	0.00e+00	694.00
IUUC-Cin-025797	Ciona intestinalis	50.43	5.00e-95	340.00
IUUC-Csv-026132	Ciona savignyi	50.43	3.00e-97	349.00
IUUC-Dre-027872	Danio rerio	81.23	6.00e-163	566.00
IUUC-Dno-029329	Dasypus novemcinctus	90.43	0.00e+00	1040.00
IUUC-Dor-030574	Dipodomys ordii	90.92	0.00e+00	1032.00
IUUC-Dme-032208	Drosophila melanogaster	46.31	7.00e-82	298.00
IUUC-Ete-032725	Echinops telfairi	80.39	7.00e-172	597.00
IUUC-Eca-033361	Equus caballus	94.39	0.00e+00	1094.00
IUUC-Eeu-035272	Erinaceus europaeus	77.93	0.00e+00	694.00
IUUC-Fca-036497	Felis catus	93.56	0.00e+00	1086.00
IUUC-Fal-036766	Ficedula albicollis	63.73	0.00e+00	680.00
IUUC-Gmo-039129	Gadus morhua	61.39	3.00e-123	434.00
IUUC-Gga-040889	Gallus gallus	83.72	3.00e-147	514.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.83	5.00e-137	480.00
IUUC-Ggo-044814	Gorilla gorilla	93.97	2.00e-180	624.00
IUUC-Hsa-045937	Homo sapiens	96.86	0.00e+00	1098.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	91.99	0.00e+00	1091.00
IUUC-Lch-050527	Latimeria chalumnae	60.46	2.00e-178	619.00
IUUC-Loc-052697	Lepisosteus oculatus	78.86	6.00e-162	564.00
IUUC-Lma-053021	Leptosphaeria maculans	34.40	3.00e-52	200.00
IUUC-Laf-054167	Loxodonta africana	86.84	0.00e+00	1011.00
IUUC-Mcc-055584	Macaca mulatta	99.83	0.00e+00	1162.00
IUUC-Meu-056542	Macropus eugenii	85.34	0.00e+00	937.00
IUUC-Mga-060020	Meleagris gallopavo	59.42	0.00e+00	635.00
IUUC-Mmr-060989	Microcebus murinus	94.39	0.00e+00	1093.00
IUUC-Mdo-062761	Monodelphis domestica	85.83	0.00e+00	945.00
IUUC-Mmu-063710	Mus musculus	89.18	0.00e+00	1036.00
IUUC-Mpu-066573	Mustela putorius furo	93.56	0.00e+00	1086.00
IUUC-Nle-070013	Nomascus leucogenys	97.22	0.00e+00	1078.00
IUUC-Opr-070907	Ochotona princeps	90.12	0.00e+00	1008.00
IUUC-Ont-071944	Oreochromis niloticus	81.56	1.00e-164	572.00
IUUC-Oan-073105	Ornithorhynchus anatinus	78.47	3.00e-147	514.00
IUUC-Ocu-073941	Oryctolagus cuniculus	91.93	0.00e+00	1056.00
IUUC-Ola-087412	Oryzias latipes	75.00	1.00e-154	540.00
IUUC-Oga-088973	Otolemur garnettii	93.89	0.00e+00	1090.00
IUUC-Oar-089916	Ovis aries	90.92	0.00e+00	1052.00
IUUC-Ptr-090998	Pan troglodytes	97.19	0.00e+00	1106.00
IUUC-Psi-093284	Pelodiscus sinensis	71.07	2.00e-123	435.00
IUUC-Pma-094462	Petromyzon marinus	64.71	7.00e-74	269.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.42	5.00e-40	159.00
IUUC-Pfo-097352	Poecilia formosa	79.21	6.00e-169	587.00
IUUC-Pab-098688	Pongo abelii	90.58	0.00e+00	993.00
IUUC-Pca-100205	Procavia capensis	93.37	0.00e+00	640.00
IUUC-Pva-103188	Pteropus vampyrus	93.40	0.00e+00	1048.00
IUUC-Pte-104348	Pyrenophora teres	33.13	3.00e-39	157.00
IUUC-Rno-105853	Rattus norvegicus	89.97	0.00e+00	1080.00
IUUC-Sha-107237	Sarcophilus harrisii	85.17	0.00e+00	935.00
IUUC-Sar-113103	Sorex araneus	91.35	0.00e+00	627.00
IUUC-Ssc-115955	Sus scrofa	92.24	0.00e+00	1065.00
IUUC-Tgu-116894	Taeniopygia guttata	69.72	5.00e-180	623.00
IUUC-Tru-117703	Takifugu rubripes	66.08	3.00e-133	468.00
IUUC-Tsy-118879	Tarsius syrichta	96.64	0.00e+00	845.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.30	3.00e-153	534.00
IUUC-Tbe-127367	Tupaia belangeri	83.73	0.00e+00	655.00
IUUC-Ttr-128773	Tursiops truncatus	89.11	0.00e+00	1044.00
IUUC-Vpa-130402	Vicugna pacos	82.68	0.00e+00	788.00
IUUC-Xtr-132658	Xenopus tropicalis	57.12	2.00e-179	622.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence