iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090445

Ensembl Protein ID

ENSOARP00000000333.1

UniProt Accession

W5NQ93; W5NQ93_SHEEP

Genbank Protein ID

ENSOARP00000000333

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01107863

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000000337.1	ENSOART00000000359.1	ENSOARP00000000333.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	96.89	0.00e+00	2303.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

IAVVEMSDAF RQPSLFYHLG VRESFSMANN IILYCDTNSD SLQSLKEIIC QKNTMCTGNY 60
TFIPYMITPH NKVYCCDSSF MKGLTELMQP NFELLLGPIC LPLVDRFIQL LKVAQASSSQ 120

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Nucleotide Sequence
(Fasta)

CGCTGGGAGC AGCGCCACCC GGTGCCGGGG CAACTCTGGG GGCGGAGGCG GCCGACGGAC 60
CACGGTGGCC TATGTCATCA ACGAGGCGAG CCAGGGGCAG CTGGTGGTGG CCGAGAGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	97.37	0.00e+00	2224.00
IUUC-Apl-003713	Anas platyrhynchos	89.63	0.00e+00	2087.00
IUUC-Aca-005331	Anolis carolinensis	88.62	0.00e+00	2105.00
IUUC-Ame-011158	Astyanax mexicanus	76.35	0.00e+00	1781.00
IUUC-Bta-012770	Bos taurus	99.59	0.00e+00	2366.00
IUUC-Cja-019656	Callithrix jacchus	96.57	0.00e+00	2296.00
IUUC-Cfa-020488	Canis familiaris	96.81	0.00e+00	2307.00
IUUC-Cpo-022516	Cavia porcellus	95.01	0.00e+00	2196.00
IUUC-Csa-023104	Chlorocebus sabaeus	96.80	0.00e+00	2305.00
IUUC-Cho-024379	Choloepus hoffmanni	89.72	0.00e+00	1236.00
IUUC-Dre-028836	Danio rerio	76.12	0.00e+00	1815.00
IUUC-Dno-029842	Dasypus novemcinctus	94.36	0.00e+00	2212.00
IUUC-Dor-030990	Dipodomys ordii	95.11	0.00e+00	1936.00
IUUC-Ete-032693	Echinops telfairi	85.31	0.00e+00	1802.00
IUUC-Eca-033337	Equus caballus	96.32	0.00e+00	2332.00
IUUC-Eeu-034602	Erinaceus europaeus	80.54	0.00e+00	1854.00
IUUC-Fca-035954	Felis catus	96.29	0.00e+00	1941.00
IUUC-Fal-037358	Ficedula albicollis	89.05	0.00e+00	2121.00
IUUC-Gmo-038836	Gadus morhua	81.31	0.00e+00	1679.00
IUUC-Gga-040443	Gallus gallus	89.38	0.00e+00	2152.00
IUUC-Gac-041634	Gasterosteus aculeatus	77.99	0.00e+00	1879.00
IUUC-Ggo-045263	Gorilla gorilla	94.70	0.00e+00	2224.00
IUUC-Hsa-046906	Homo sapiens	96.81	0.00e+00	2306.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	94.86	0.00e+00	1102.00
IUUC-Lch-050213	Latimeria chalumnae	78.87	0.00e+00	1817.00
IUUC-Loc-051829	Lepisosteus oculatus	76.38	0.00e+00	1805.00
IUUC-Laf-053538	Loxodonta africana	96.40	0.00e+00	2288.00
IUUC-Mcc-054776	Macaca mulatta	96.81	0.00e+00	2307.00
IUUC-Mga-059636	Meleagris gallopavo	89.30	0.00e+00	2150.00
IUUC-Mmr-061323	Microcebus murinus	96.41	0.00e+00	2255.00
IUUC-Mdo-062146	Monodelphis domestica	95.34	0.00e+00	2203.00
IUUC-Mmu-064022	Mus musculus	95.91	0.00e+00	2269.00
IUUC-Mpu-066531	Mustela putorius furo	94.19	0.00e+00	2298.00
IUUC-Mlu-068181	Myotis lucifugus	94.85	0.00e+00	2274.00
IUUC-Nle-069758	Nomascus leucogenys	96.72	0.00e+00	2301.00
IUUC-Opr-070531	Ochotona princeps	87.44	0.00e+00	1460.00
IUUC-Ont-072014	Oreochromis niloticus	78.66	0.00e+00	1843.00
IUUC-Oan-073169	Ornithorhynchus anatinus	94.03	0.00e+00	2249.00
IUUC-Ocu-074050	Oryctolagus cuniculus	91.67	0.00e+00	2157.00
IUUC-Ola-086941	Oryzias latipes	80.63	0.00e+00	1552.00
IUUC-Oga-088796	Otolemur garnettii	96.00	0.00e+00	2249.00
IUUC-Ptr-090846	Pan troglodytes	96.97	0.00e+00	2310.00
IUUC-Pan-091986	Papio anubis	96.89	0.00e+00	2310.00
IUUC-Psi-093805	Pelodiscus sinensis	89.25	0.00e+00	2246.00
IUUC-Pfo-097301	Poecilia formosa	78.68	0.00e+00	1862.00
IUUC-Pab-097662	Pongo abelii	96.81	0.00e+00	2307.00
IUUC-Pca-100755	Procavia capensis	94.92	0.00e+00	734.00
IUUC-Pva-102280	Pteropus vampyrus	87.25	0.00e+00	2034.00
IUUC-Rno-105547	Rattus norvegicus	94.60	0.00e+00	2248.00
IUUC-Sha-106859	Sarcophilus harrisii	94.69	0.00e+00	2163.00
IUUC-Sar-113714	Sorex araneus	83.80	0.00e+00	1937.00
IUUC-Tgu-117116	Taeniopygia guttata	87.92	0.00e+00	2088.00
IUUC-Tru-118088	Takifugu rubripes	77.65	0.00e+00	1882.00
IUUC-Tsy-119616	Tarsius syrichta	91.16	0.00e+00	1837.00
IUUC-Tni-120284	Tetraodon nigroviridis	76.28	0.00e+00	1844.00
IUUC-Tbe-127900	Tupaia belangeri	95.79	0.00e+00	858.00
IUUC-Ttr-128294	Tursiops truncatus	86.68	0.00e+00	1988.00
IUUC-Vpa-130470	Vicugna pacos	88.48	0.00e+00	2038.00
IUUC-Xtr-132396	Xenopus tropicalis	79.98	0.00e+00	1899.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence