iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004612

UUCD1 version

UUC-AnC-01000

Ensembl Protein ID

ENSACAP00000004141.2

UniProt Accession

H9G8P9; H9G8P9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004099.3	ENSACAT00000004240.3	ENSACAP00000004141.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.80e-92	307.6	238	586

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mN+vLQcLs++++lr+++l+ +++++ +      +++el+++++++++ lw  ++++a +p++++++++k+ ++f+gy+
   Q: 238  GLRNLGNTCFMNAVLQCLSSTKPLRDYCLRrEFRQEQPG--ALRTQQELTEAFADVIATLWhPDSTEAANPSRFKAIFQKYVPSFTGYS 324
           9*****************************444444444..38899***************888999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde......................aeekkkkknkslisdlFqgqlksqik 155
           qqDaqEfl+fl+d+l+ e++++ +k+ + ++++++ +  ++                        ++  k +   + dlF gqlks +k
   Q: 325  QQDAQEFLKFLMDRLHVEINRKGRKTPSILSDAKRASVLEDadilrihkhiyieedenhdlirVGQSYLKFELYSLPDLFVGQLKSCLK 413
           *******************99666666666555554444446889999999999998888888888888888899************** PP
   S: 156  clecdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeq 243
           c+ c+ +s+++e f+dlslp+p+k  t  k sl dc++ ftkeeel++en+ +c+kc+++++++kkl+++++P++L+lhL+Rf  s ++
   Q: 414  CQVCGYRSTTFEVFCDLSLPIPKKGFTgGKVSLLDCFSLFTKEEELDSENAPECDKCRQRTRSTKKLTIQRFPRILVLHLNRF--STTR 500
           **********************887551456****************************************************..6677 PP
   S: 244  ksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaY 331
           +s +k++  v+fpl+ L+l++f +++      +  Y+L+a ++HsGs++  HY+a++k+ + +W  ++Ds+V++++e++v +   s++Y
   Q: 501  YSIKKCSVFVDFPLQqLNLKEFASEKAG----TPVYNLYALCNHSGSVHYDHYTAFCKD-QSGWRVYNDSRVSPISENQVPS---SEGY 581
           899***********99*******99443....79*************************.777*******************...**** PP
   S: 332  vlfYk 336
           vlfY+
   Q: 582  VLFYE 586
           ****8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPQASEHRMS RAREQAVITS QPKANSKLPN AHRAPSQEHR NCCSSSSISN GLSGPSKLRP 60
LPPRPTPLDD RGKKLETDRG RASKHSDVPR GPTSRRGPIK ADHALKIPSC PQPGGPDSDQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCAAG CGTCTGAGCA CCGCATGAGC CGGGCGAGAG AGCAAGCAGT CATCACCTCT 60
CAGCCAAAGG CCAACAGCAA GCTCCCAAAT GCACACCGAG CTCCGAGTCA AGAGCACCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	58.28	5.00e-169	587.00
IUUC-Bta-012626	Bos taurus	57.21	7.00e-165	573.00
IUUC-Cja-018853	Callithrix jacchus	58.28	9.00e-171	593.00
IUUC-Cfa-021167	Canis familiaris	58.83	1.00e-167	583.00
IUUC-Cpo-021305	Cavia porcellus	59.50	2.00e-169	588.00
IUUC-Csa-023454	Chlorocebus sabaeus	59.00	8.00e-171	593.00
IUUC-Cho-024836	Choloepus hoffmanni	80.54	2.00e-86	312.00
IUUC-Dre-028454	Danio rerio	49.72	1.00e-99	356.00
IUUC-Dno-029955	Dasypus novemcinctus	53.96	2.00e-169	588.00
IUUC-Dor-031053	Dipodomys ordii	59.67	3.00e-177	614.00
IUUC-Ete-032416	Echinops telfairi	68.15	4.00e-104	371.00
IUUC-Eca-033817	Equus caballus	58.33	9.00e-169	586.00
IUUC-Fca-036400	Felis catus	58.47	8.00e-165	573.00
IUUC-Gmo-038926	Gadus morhua	50.28	6.00e-95	340.00
IUUC-Gac-041331	Gasterosteus aculeatus	48.33	5.00e-98	350.00
IUUC-Ggo-045174	Gorilla gorilla	59.00	8.00e-171	593.00
IUUC-Hsa-046443	Homo sapiens	58.83	3.00e-169	588.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	59.04	1.00e-169	589.00
IUUC-Lch-050539	Latimeria chalumnae	61.76	8.00e-105	374.00
IUUC-Loc-051808	Lepisosteus oculatus	51.37	2.00e-108	385.00
IUUC-Laf-053730	Loxodonta africana	58.54	2.00e-172	598.00
IUUC-Mcc-055541	Macaca mulatta	59.00	8.00e-171	593.00
IUUC-Meu-056279	Macropus eugenii	58.53	9.00e-176	609.00
IUUC-Mmr-060913	Microcebus murinus	59.17	5.00e-168	583.00
IUUC-Mdo-061807	Monodelphis domestica	58.89	2.00e-164	572.00
IUUC-Mmu-063599	Mus musculus	58.90	7.00e-166	577.00
IUUC-Mpu-066329	Mustela putorius furo	59.00	1.00e-167	582.00
IUUC-Mlu-067359	Myotis lucifugus	56.57	2.00e-152	532.00
IUUC-Nle-070084	Nomascus leucogenys	58.29	1.00e-164	573.00
IUUC-Opr-071096	Ochotona princeps	58.12	5.00e-167	580.00
IUUC-Ocu-074228	Oryctolagus cuniculus	58.71	6.00e-169	587.00
IUUC-Ola-086684	Oryzias latipes	46.41	2.00e-92	332.00
IUUC-Oga-088007	Otolemur garnettii	56.39	1.00e-132	466.00
IUUC-Oar-090226	Ovis aries	54.60	2.00e-125	442.00
IUUC-Ptr-091522	Pan troglodytes	59.00	8.00e-171	593.00
IUUC-Pan-091954	Papio anubis	58.67	1.00e-168	586.00
IUUC-Psi-093216	Pelodiscus sinensis	72.78	0.00e+00	848.00
IUUC-Pab-098691	Pongo abelii	59.00	8.00e-171	593.00
IUUC-Pca-101133	Procavia capensis	53.74	3.00e-150	525.00
IUUC-Pva-102681	Pteropus vampyrus	56.28	2.00e-159	555.00
IUUC-Rno-105132	Rattus norvegicus	59.03	3.00e-170	591.00
IUUC-Sha-107145	Sarcophilus harrisii	57.02	5.00e-159	553.00
IUUC-Ssc-115586	Sus scrofa	58.67	5.00e-166	577.00
IUUC-Tgu-117491	Taeniopygia guttata	77.64	2.00e-108	384.00
IUUC-Tni-120746	Tetraodon nigroviridis	49.41	3.00e-86	311.00
IUUC-Tbe-127465	Tupaia belangeri	76.56	2.00e-93	336.00
IUUC-Ttr-128274	Tursiops truncatus	56.83	2.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence