iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000006258.1	ENSLACT00000007110.1	ENSLACP00000007051.1
ENSLACG00000006258.1	ENSLACT00000007111.1	ENSLACP00000007052.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.30e-67	225.8	233	559

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 21   nipelrellle..........kkkeklneenp.kepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEfla 97
           ++++++++ l+          +    +++  p +++ +  ++s+++++ +lw  ++ ++v+p +++ +++k+ + f+g++qqDaqEfl+
   Q: 233  FCNSFKSFTLSlslslslsyiH---CTEKATPfSSDFNFQMDSFADVLLALWkPDSCEVVNPGKFKGVFQKYVPYFTGFSQQDAQEFLR 318
           5555555555555544442221...11111112344455678999999999*778889******************************* PP
   S: 98   flldqleeelkk............eknkpkeeeeeedkselsde...........aeekkkkknkslisdlFqgqlksqikclecdnvs 163
           fl+d+l++e+++             ++++ e+                        +++  ++++s i+dlF gqlks++kc  c+n+s
   Q: 319  FLMDRLHNEINRksrrtpsimvatARQSSLED-----------LeklrddekaiqMWKRYLEREDSKIVDLFVGQLKSSLKCTVCGNKS 396
           **********9865555554444433333333...........2555555666669********************************* PP
   S: 164  sreepfldlslpvpgkeetkkeslqdcLesftkeee..legenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekin 250
           + +e f+dlslp+p+       s   c    t +++  +  +n   c+kc +k++++kkl+++++P++L+lhL+Rf  s +++s +k++
   Q: 397  TMFEVFCDLSLPIPKVIAP---SGCCCPVLVTDPCHcgVFLANTQMCDKCGEKKKSTKKLTIQRFPKILVLHLNRF--STTRYSIKKCS 480
           **************99976...33333344444443113346889*******************************..6677899**** PP
   S: 251  kkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
            +vefpl+ L+l+ f t++      +  Y+L+av++HsG++++GHY+a++++   +W +++Ds+V++++ ++vl+   s+aYvlfY+
   Q: 481  VYVEFPLQgLNLRDFATEKAG----NAVYNLYAVCNHSGTVHGGHYTAHCRD-PSGWHNYNDSRVSSIHDNQVLS---SEAYVLFYE 559
           ******************554....68*************************.566*******************...********8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MPQASAARFT PNVTQSVIAN KSKPSSKMAS GQRASSKEQQ RNSTSTSSGA SILSTPSTKP 60
RPLPPGPGPL DEQGRKLETD RGRSLRRSDQ IRTSTSKRGP MKADHNVGVS YSGQSHGISV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTCAGG CCTCTGCTGC CAGGTTTACT CCAAATGTGA CGCAGTCGGT TATTGCCAAC 60
AAGTCAAAAC CATCTTCCAA AATGGCTTCC GGGCAACGAG CATCAAGCAA GGAACAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	62.33	5.00e-106	378.00
IUUC-Aca-004612	Anolis carolinensis	61.76	2.00e-105	376.00
IUUC-Bta-012626	Bos taurus	61.67	2.00e-104	372.00
IUUC-Cja-018853	Callithrix jacchus	62.00	5.00e-105	374.00
IUUC-Cfa-021167	Canis familiaris	62.00	8.00e-103	367.00
IUUC-Cpo-021305	Cavia porcellus	62.00	2.00e-105	376.00
IUUC-Csa-023454	Chlorocebus sabaeus	62.00	4.00e-105	375.00
IUUC-Cho-024836	Choloepus hoffmanni	60.96	1.00e-56	213.00
IUUC-Dor-031053	Dipodomys ordii	62.00	2.00e-105	376.00
IUUC-Ete-032416	Echinops telfairi	62.12	4.00e-86	311.00
IUUC-Eca-033817	Equus caballus	61.33	4.00e-105	375.00
IUUC-Fca-036400	Felis catus	61.46	2.00e-101	362.00
IUUC-Ggo-045174	Gorilla gorilla	62.00	4.00e-105	375.00
IUUC-Hsa-046443	Homo sapiens	62.00	3.00e-105	375.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	63.00	6.00e-107	381.00
IUUC-Laf-053730	Loxodonta africana	61.06	9.00e-104	370.00
IUUC-Mcc-055541	Macaca mulatta	62.00	4.00e-105	375.00
IUUC-Meu-056279	Macropus eugenii	61.67	5.00e-105	374.00
IUUC-Mor-057065	Magnaporthe oryzae	30.04	7.00e-26	112.00
IUUC-Mmr-060913	Microcebus murinus	62.00	2.00e-104	372.00
IUUC-Mdo-061807	Monodelphis domestica	62.00	9.00e-106	377.00
IUUC-Mmu-063599	Mus musculus	61.76	9.00e-106	377.00
IUUC-Mpu-066329	Mustela putorius furo	62.00	8.00e-103	367.00
IUUC-Nle-070084	Nomascus leucogenys	61.33	2.00e-101	362.00
IUUC-Opr-071096	Ochotona princeps	61.67	3.00e-104	372.00
IUUC-Ocu-074228	Oryctolagus cuniculus	62.67	1.00e-105	376.00
IUUC-Oga-088007	Otolemur garnettii	56.52	7.00e-91	327.00
IUUC-Ptr-091522	Pan troglodytes	62.00	4.00e-105	375.00
IUUC-Pan-091954	Papio anubis	61.67	2.00e-103	369.00
IUUC-Psi-093216	Pelodiscus sinensis	69.59	5.00e-120	424.00
IUUC-Pab-098691	Pongo abelii	62.00	3.00e-105	375.00
IUUC-Pca-101133	Procavia capensis	61.41	2.00e-104	373.00
IUUC-Pva-102681	Pteropus vampyrus	59.67	7.00e-98	351.00
IUUC-Rno-105132	Rattus norvegicus	62.00	9.00e-105	374.00
IUUC-Sha-107145	Sarcophilus harrisii	62.01	4.00e-97	348.00
IUUC-Ssc-115586	Sus scrofa	62.13	3.00e-100	358.00
IUUC-Tbe-127465	Tupaia belangeri	65.07	2.00e-74	273.00
IUUC-Ttr-128274	Tursiops truncatus	61.00	9.00e-104	370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence