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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063117
Ensembl Protein ID ENSMUSP00000103442.1
UniProt Accession Q8K057; Q6ZPT0; Q8C9F1; Q91YV4; IFT80_MOUSE
Genbank Protein ID BAC98149.1; AAH13814.1; AAH34101.1; BAC31200.1
Protein Name Intraflagellar transport protein 80 homolog; WD repeat-containing protein 56
Genbank Nucleotide ID AK129339; BC013814; BC034101; AK042231
Gene Name Ift80; Kiaa1374; Wdr56
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000027778.15 ENSMUST00000107812.7 ENSMUSP00000103442.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.50e-12 47.6 228 256
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 228  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 256
           99*********9978888887.689*9999 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
 Component of the intraflagellar transport (IFT) complex B, which is essential for the development and maintenance of motile and sensory cilia.
Protein Sequence
(Fasta)
MRLKISLSKE PKHQELVSCV GWTTAEELYS CSDDHQIVKW NLLTSETSLI VKLPDDIYPI 60
DLHWFPKSLG IKKQTQAESF VLTSSDGKFH LISKLGRVEK SVEAHCGAVL AGRWNYEGTA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063117|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGCAAGTAT CGCGGGAACA TGGCAGGGGG AAACGCTCGC AGCGCTTAGA AATCACTATG 60
GTGACGGAAA GGTCGGGAGG CTATTTGGTA ACTAGTTCGA GCTCTGAGAG CAGTCGCCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063117|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0966--Cell projection
KW-0969--Cilium
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0005737--C:cytoplasm
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0060271--P:cilium assembly
GO:0042073--P:intraciliary transport
GO:0035735--P:intraciliary transport involved in cilium assembly
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway
KEGG mmu:68259
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001564 Ailuropoda melanoleuca 97.29 0.00e+00 896.00
IUUC-Apl-003721 Anas platyrhynchos 85.31 0.00e+00 1375.00
IUUC-Aca-004488 Anolis carolinensis 85.54 0.00e+00 1385.00
IUUC-Ame-011402 Astyanax mexicanus 81.74 0.00e+00 824.00
IUUC-Bta-013037 Bos taurus 85.62 0.00e+00 1315.00
IUUC-Cel-018360 Caenorhabditis elegans 40.92 0.00e+00 664.00
IUUC-Cja-019076 Callithrix jacchus 91.68 0.00e+00 1206.00
IUUC-Cfa-020999 Canis familiaris 95.41 0.00e+00 1509.00
IUUC-Cpo-021333 Cavia porcellus 85.23 0.00e+00 1286.00
IUUC-Cre-022899 Chlamydomonas reinhardtii 46.47 0.00e+00 680.00
IUUC-Csa-023699 Chlorocebus sabaeus 94.76 0.00e+00 1496.00
IUUC-Cho-024904 Choloepus hoffmanni 87.83 0.00e+00 828.00
IUUC-Cin-025399 Ciona intestinalis 57.03 0.00e+00 954.00
IUUC-Csv-026186 Ciona savignyi 55.19 0.00e+00 924.00
IUUC-Dre-028276 Danio rerio 74.71 0.00e+00 1267.00
IUUC-Dno-029824 Dasypus novemcinctus 95.80 0.00e+00 1515.00
IUUC-Dor-031141 Dipodomys ordii 90.99 0.00e+00 1425.00
IUUC-Dme-031620 Drosophila melanogaster 35.42 2.00e-142 499.00
IUUC-Eca-033339 Equus caballus 94.34 0.00e+00 1489.00
IUUC-Eeu-034909 Erinaceus europaeus 93.42 0.00e+00 994.00
IUUC-Fca-035780 Felis catus 95.95 0.00e+00 1487.00
IUUC-Fal-037447 Ficedula albicollis 79.00 0.00e+00 1263.00
IUUC-Gmo-038657 Gadus morhua 61.16 0.00e+00 831.00
IUUC-Gga-040689 Gallus gallus 85.92 0.00e+00 1380.00
IUUC-Gac-041586 Gasterosteus aculeatus 72.40 0.00e+00 1004.00
IUUC-Hsa-047005 Homo sapiens 94.72 0.00e+00 1517.00
IUUC-Itr-048757 Ictidomys tridecemlineatus 96.09 0.00e+00 1116.00
IUUC-Lch-050459 Latimeria chalumnae 80.50 0.00e+00 1311.00
IUUC-Loc-052774 Lepisosteus oculatus 77.44 0.00e+00 1054.00
IUUC-Laf-053765 Loxodonta africana 94.39 0.00e+00 1459.00
IUUC-Mcc-055052 Macaca mulatta 94.76 0.00e+00 1496.00
IUUC-Meu-056368 Macropus eugenii 80.87 0.00e+00 1264.00
IUUC-Mga-059488 Meleagris gallopavo 85.81 0.00e+00 1380.00
IUUC-Mmr-061527 Microcebus murinus 94.89 0.00e+00 1492.00
IUUC-Mdo-062850 Monodelphis domestica 93.66 0.00e+00 1212.00
IUUC-Mpu-066550 Mustela putorius furo 95.37 0.00e+00 1372.00
IUUC-Mlu-067772 Myotis lucifugus 91.20 0.00e+00 1396.00
IUUC-Nle-069215 Nomascus leucogenys 94.07 0.00e+00 1506.00
IUUC-Opr-070725 Ochotona princeps 73.56 0.00e+00 1113.00
IUUC-Ont-072147 Oreochromis niloticus 73.40 0.00e+00 1250.00
IUUC-Oan-073176 Ornithorhynchus anatinus 87.10 2.00e-63 233.00
IUUC-Ocu-073896 Oryctolagus cuniculus 94.60 0.00e+00 1220.00
IUUC-Ola-086767 Oryzias latipes 68.11 0.00e+00 951.00
IUUC-Oga-088113 Otolemur garnettii 95.03 0.00e+00 1514.00
IUUC-Oar-089683 Ovis aries 91.03 0.00e+00 1435.00
IUUC-Ptr-091563 Pan troglodytes 95.14 0.00e+00 1515.00
IUUC-Pan-092042 Papio anubis 94.76 0.00e+00 1495.00
IUUC-Psi-093306 Pelodiscus sinensis 86.37 0.00e+00 1434.00
IUUC-Ppa-095694 Physcomitrella patens 44.79 0.00e+00 711.00
IUUC-Pfo-096800 Poecilia formosa 72.40 0.00e+00 1235.00
IUUC-Pab-098356 Pongo abelii 94.59 0.00e+00 1513.00
IUUC-Pva-102246 Pteropus vampyrus 90.76 0.00e+00 1404.00
IUUC-Rno-105195 Rattus norvegicus 98.20 0.00e+00 1545.00
IUUC-Sha-107056 Sarcophilus harrisii 93.98 0.00e+00 1487.00
IUUC-Smo-109240 Selaginella moellendorffii 43.99 1.00e-173 603.00
IUUC-Sar-113301 Sorex araneus 83.67 5.00e-146 511.00
IUUC-Ssc-116040 Sus scrofa 96.46 2.00e-146 511.00
IUUC-Tgu-117127 Taeniopygia guttata 81.02 0.00e+00 1314.00
IUUC-Tru-118663 Takifugu rubripes 70.42 0.00e+00 1194.00
IUUC-Tsy-119207 Tarsius syrichta 83.27 0.00e+00 1300.00
IUUC-Tni-120705 Tetraodon nigroviridis 69.28 0.00e+00 1182.00
IUUC-Tbe-127434 Tupaia belangeri 85.53 0.00e+00 942.00
IUUC-Ttr-128937 Tursiops truncatus 95.37 0.00e+00 1509.00
IUUC-Vpa-130518 Vicugna pacos 90.48 0.00e+00 1392.00
IUUC-Xtr-131879 Xenopus tropicalis 76.41 0.00e+00 1264.00
Created Date 25-Jun-2017

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