iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089683

Ensembl Protein ID

ENSOARP00000002232.1

UniProt Accession

W5NVN6; W5NVN6_SHEEP

Genbank Protein ID

ENSOARP00000002232

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01010373

Gene Name

IFT80

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000002110.1	ENSOART00000002283.1	ENSOARP00000002232.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-12	48.0	230	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 230  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 258
           99*********9978888887.689*9999 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MRLKISLLKE PKVTHQELVS CVGWTTAEEL YSCSDDHQIV KWNLLTGETS QIVKLPDDIY 60
PIDLHWFPKS LGIKKQTQAE IFVLTSSDGK FHLISKLGRV EKSVDAHSGA VLAGRWNYEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCTGA AGATATCTCT TTTAAAGGAA CCAAAGCATA TCCTTTTAAT ACTTATAAAC 60
CTTATTGTGA TCTCCTTATT GTAGTATTAT TAAAAGTTTT CTTCTATTTT GTAATCTAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	90.79	0.00e+00	835.00
IUUC-Apl-003721	Anas platyrhynchos	81.73	0.00e+00	1312.00
IUUC-Aca-004488	Anolis carolinensis	82.40	0.00e+00	1325.00
IUUC-Ame-011402	Astyanax mexicanus	76.39	0.00e+00	762.00
IUUC-Bta-013037	Bos taurus	87.99	0.00e+00	1341.00
IUUC-Cel-018360	Caenorhabditis elegans	39.97	0.00e+00	651.00
IUUC-Cja-019076	Callithrix jacchus	91.08	0.00e+00	1172.00
IUUC-Cfa-020999	Canis familiaris	92.87	0.00e+00	1470.00
IUUC-Cpo-021333	Cavia porcellus	81.64	0.00e+00	1238.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	46.02	0.00e+00	657.00
IUUC-Csa-023699	Chlorocebus sabaeus	92.31	0.00e+00	1457.00
IUUC-Cho-024904	Choloepus hoffmanni	80.95	0.00e+00	766.00
IUUC-Cin-025399	Ciona intestinalis	55.24	0.00e+00	926.00
IUUC-Csv-026186	Ciona savignyi	53.80	0.00e+00	899.00
IUUC-Dre-028276	Danio rerio	72.79	0.00e+00	1222.00
IUUC-Dno-029824	Dasypus novemcinctus	92.81	0.00e+00	1474.00
IUUC-Dor-031141	Dipodomys ordii	87.82	0.00e+00	1365.00
IUUC-Dme-031620	Drosophila melanogaster	35.10	3.00e-138	485.00
IUUC-Eca-033339	Equus caballus	91.67	0.00e+00	1438.00
IUUC-Eeu-034909	Erinaceus europaeus	94.59	0.00e+00	1015.00
IUUC-Fca-035780	Felis catus	92.95	0.00e+00	1437.00
IUUC-Fal-037447	Ficedula albicollis	75.63	0.00e+00	1202.00
IUUC-Gmo-038657	Gadus morhua	58.87	0.00e+00	788.00
IUUC-Gga-040689	Gallus gallus	82.51	0.00e+00	1318.00
IUUC-Gac-041586	Gasterosteus aculeatus	70.21	0.00e+00	971.00
IUUC-Hsa-047005	Homo sapiens	92.30	0.00e+00	1473.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	92.18	0.00e+00	1057.00
IUUC-Lch-050459	Latimeria chalumnae	78.53	0.00e+00	1281.00
IUUC-Loc-052774	Lepisosteus oculatus	75.36	0.00e+00	1022.00
IUUC-Laf-053765	Loxodonta africana	91.81	0.00e+00	1412.00
IUUC-Mcc-055052	Macaca mulatta	92.31	0.00e+00	1457.00
IUUC-Meu-056368	Macropus eugenii	78.15	0.00e+00	1208.00
IUUC-Mga-059488	Meleagris gallopavo	82.51	0.00e+00	1323.00
IUUC-Mmr-061527	Microcebus murinus	92.41	0.00e+00	1441.00
IUUC-Mdo-062850	Monodelphis domestica	90.94	0.00e+00	1166.00
IUUC-Mmu-063117	Mus musculus	91.03	0.00e+00	1434.00
IUUC-Mpu-066550	Mustela putorius furo	91.04	0.00e+00	1331.00
IUUC-Mlu-067772	Myotis lucifugus	88.55	0.00e+00	1351.00
IUUC-Nle-069215	Nomascus leucogenys	91.53	0.00e+00	1461.00
IUUC-Opr-070725	Ochotona princeps	70.59	0.00e+00	1065.00
IUUC-Ont-072147	Oreochromis niloticus	71.50	0.00e+00	1211.00
IUUC-Oan-073176	Ornithorhynchus anatinus	74.55	1.00e-46	177.00
IUUC-Ocu-073896	Oryctolagus cuniculus	91.40	0.00e+00	1176.00
IUUC-Ola-086767	Oryzias latipes	65.57	0.00e+00	920.00
IUUC-Oga-088113	Otolemur garnettii	92.18	0.00e+00	1474.00
IUUC-Ptr-091563	Pan troglodytes	92.94	0.00e+00	1472.00
IUUC-Pan-092042	Papio anubis	92.31	0.00e+00	1456.00
IUUC-Psi-093306	Pelodiscus sinensis	82.73	0.00e+00	1378.00
IUUC-Ppa-095694	Physcomitrella patens	43.83	0.00e+00	687.00
IUUC-Pfo-096800	Poecilia formosa	70.64	0.00e+00	1199.00
IUUC-Pab-098356	Pongo abelii	92.17	0.00e+00	1471.00
IUUC-Pva-102246	Pteropus vampyrus	87.58	0.00e+00	1358.00
IUUC-Rno-105195	Rattus norvegicus	90.89	0.00e+00	1444.00
IUUC-Sha-107056	Sarcophilus harrisii	91.03	0.00e+00	1426.00
IUUC-Smo-109240	Selaginella moellendorffii	42.60	9.00e-168	583.00
IUUC-Sar-113301	Sorex araneus	85.76	2.00e-148	520.00
IUUC-Ssc-116040	Sus scrofa	84.77	8.00e-129	452.00
IUUC-Tgu-117127	Taeniopygia guttata	77.97	0.00e+00	1259.00
IUUC-Tru-118663	Takifugu rubripes	68.13	0.00e+00	1158.00
IUUC-Tsy-119207	Tarsius syrichta	80.90	0.00e+00	1251.00
IUUC-Tni-120705	Tetraodon nigroviridis	67.14	0.00e+00	1152.00
IUUC-Tbe-127434	Tupaia belangeri	86.59	0.00e+00	892.00
IUUC-Ttr-128937	Tursiops truncatus	93.08	0.00e+00	1474.00
IUUC-Vpa-130518	Vicugna pacos	87.31	0.00e+00	1348.00
IUUC-Xtr-131879	Xenopus tropicalis	74.12	0.00e+00	1219.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence