iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000055239.10	ENSMUST00000068697.10	ENSMUSP00000064410.8
ENSMUSG00000055239.10	ENSMUST00000206378.1	ENSMUSP00000145559.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
miRNAMap	RAID2
Protein-protein Interaction
IID	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	97.38	3.00e-167	585.00	IUUC-Hsa-046934

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

Protein Sequence
(Fasta)

MSRHEGVSCD ACLKGNFRGR RYKCLICYDY DLCASCYESG ATTTRHTTDH PMQCILTRVD 60
FDLYYGGEAF SVEQPQSFTC PYCGKMGYTE TSLQEHVTSE HAETSTEVIC PICAALPGGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGGACGA GCGGGATTTG CGGACGCCGC GCCGCTGCCG GGAGCCGGCG GGGGCCCGAG 60
AGTGACCGAG TCACGGCGGG CGCCGGCGGA GCCGCGGCCG CGTCGGACCC GCCTCCTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008598--Di19_Zn_binding_dom
IPR023413--GFP-like
IPR013087--Znf_C2H2_type
IPR000433--Znf_ZZ

PROSITE

PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF05605--zf-Di19
PF00569--ZZ

SMART

SM00355--ZnF_C2H2
SM00291--ZnF_ZZ

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

KEGG

mmu:74287

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001353	Ailuropoda melanoleuca	94.82	6.00e-160	556.00
IUUC-Apl-003901	Anas platyrhynchos	94.41	2.00e-156	545.00
IUUC-Aca-004248	Anolis carolinensis	96.33	1.00e-166	579.00
IUUC-Ago-007828	Ashbya gossypii	40.35	5.00e-08	52.80
IUUC-Ame-011415	Astyanax mexicanus	87.47	1.00e-152	532.00
IUUC-Bta-013276	Bos taurus	97.07	9.00e-163	566.00
IUUC-Cel-018128	Caenorhabditis elegans	42.28	4.00e-26	112.00
IUUC-Cja-019677	Callithrix jacchus	96.06	3.00e-162	564.00
IUUC-Cfa-020340	Canis familiaris	94.82	3.00e-160	557.00
IUUC-Cpo-022501	Cavia porcellus	95.76	1.00e-157	549.00
IUUC-Cho-024320	Choloepus hoffmanni	96.31	3.00e-162	564.00
IUUC-Cin-025388	Ciona intestinalis	53.10	9.00e-87	313.00
IUUC-Csv-026332	Ciona savignyi	58.91	6.00e-79	286.00
IUUC-Dre-027830	Danio rerio	88.25	3.00e-153	534.00
IUUC-Dno-028990	Dasypus novemcinctus	97.27	1.00e-132	465.00
IUUC-Dor-030302	Dipodomys ordii	100.00	4.00e-45	174.00
IUUC-Dme-031795	Drosophila melanogaster	64.73	1.00e-73	271.00
IUUC-Ete-032538	Echinops telfairi	85.38	2.00e-132	465.00
IUUC-Eca-034000	Equus caballus	94.49	3.00e-158	550.00
IUUC-Fca-035462	Felis catus	95.28	1.00e-168	585.00
IUUC-Fal-036863	Ficedula albicollis	93.64	1.00e-127	449.00
IUUC-Gmo-038498	Gadus morhua	84.85	9.00e-101	360.00
IUUC-Gga-040163	Gallus gallus	93.44	7.00e-152	530.00
IUUC-Gac-042174	Gasterosteus aculeatus	79.28	1.00e-136	479.00
IUUC-Ggo-044452	Gorilla gorilla	95.34	3.00e-163	567.00
IUUC-Hsa-046934	Homo sapiens	97.38	3.00e-168	584.00
IUUC-Itr-048334	Ictidomys tridecemlineatus	93.50	1.00e-91	328.00
IUUC-Lch-049543	Latimeria chalumnae	93.23	8.00e-150	523.00
IUUC-Loc-052359	Lepisosteus oculatus	91.60	1.00e-144	505.00
IUUC-Laf-053512	Loxodonta africana	96.56	1.00e-158	552.00
IUUC-Mcc-055169	Macaca mulatta	96.06	5.00e-165	573.00
IUUC-Meu-056818	Macropus eugenii	100.00	1.00e-82	299.00
IUUC-Mga-059457	Meleagris gallopavo	90.55	3.00e-142	498.00
IUUC-Mmr-061484	Microcebus murinus	85.98	3.00e-135	474.00
IUUC-Mdo-062325	Monodelphis domestica	94.78	5.00e-165	573.00
IUUC-Mpu-066640	Mustela putorius furo	97.66	2.00e-91	328.00
IUUC-Mlu-068090	Myotis lucifugus	94.78	1.00e-159	555.00
IUUC-Nle-069910	Nomascus leucogenys	96.06	6.00e-165	573.00
IUUC-Opr-071068	Ochotona princeps	96.54	1.00e-165	575.00
IUUC-Ont-071862	Oreochromis niloticus	80.46	2.00e-143	502.00
IUUC-Oan-072982	Ornithorhynchus anatinus	96.54	7.00e-162	563.00
IUUC-Ocu-074060	Oryctolagus cuniculus	96.67	1.00e-132	465.00
IUUC-Ola-086322	Oryzias latipes	72.31	2.00e-109	389.00
IUUC-Oga-088633	Otolemur garnettii	96.83	2.00e-161	561.00
IUUC-Oar-090084	Ovis aries	96.04	3.00e-160	558.00
IUUC-Ptr-090479	Pan troglodytes	97.34	3.00e-165	574.00
IUUC-Pan-092681	Papio anubis	96.06	5.00e-165	573.00
IUUC-Psi-093474	Pelodiscus sinensis	95.29	1.00e-157	548.00
IUUC-Pma-094419	Petromyzon marinus	63.50	2.00e-112	399.00
IUUC-Ppa-095709	Physcomitrella patens	30.93	1.00e-06	46.60
IUUC-Pfo-096843	Poecilia formosa	78.61	7.00e-130	456.00
IUUC-Pab-098186	Pongo abelii	96.97	5.00e-135	473.00
IUUC-Pca-100929	Procavia capensis	95.49	8.00e-154	536.00
IUUC-Pva-102933	Pteropus vampyrus	95.96	9.00e-133	466.00
IUUC-Rno-105475	Rattus norvegicus	99.73	2.00e-168	584.00
IUUC-Sha-106466	Sarcophilus harrisii	95.28	5.00e-163	566.00
IUUC-Sar-113598	Sorex araneus	84.21	5.00e-120	424.00
IUUC-Ssc-116196	Sus scrofa	95.83	1.00e-161	562.00
IUUC-Tgu-116780	Taeniopygia guttata	92.57	2.00e-153	535.00
IUUC-Tru-118235	Takifugu rubripes	79.95	9.00e-142	496.00
IUUC-Tsy-118950	Tarsius syrichta	100.00	3.00e-82	298.00
IUUC-Tni-120161	Tetraodon nigroviridis	73.61	4.00e-113	401.00
IUUC-Tbe-128152	Tupaia belangeri	94.96	8.00e-158	549.00
IUUC-Ttr-128348	Tursiops truncatus	96.57	8.00e-162	563.00
IUUC-Vpa-130228	Vicugna pacos	84.67	4.00e-86	311.00
IUUC-Xtr-131931	Xenopus tropicalis	93.70	1.00e-151	529.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence