iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002059

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01010203

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000015834.1	ENSAMET00000017402.1	ENSAMEP00000016712.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	3.90e-48	163.4	41	230

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
224		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA+++s                                                          ll+vf+d+s sd
   Q: 41   AIRKTKGDGNCFYRALGYSylesllgksrevlkfkervlqtpndllaagfeehkfrnffnafysvvelvekdssvssLLKVFNDQSSSD 129
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts++++++++ff++fi+e++d+k+fc+++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++ +
   Q: 130  QIVQFLRLLTSAFIKNRAEFFRHFIDEEMDIKDFCTHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-T 213
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 214  PSVYLLYKTSHYNILYA 230
           ***************97 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

QSETSFNLIS EKCDILSILR DHPENRIYQR KIQELSKRFT AIRKTKGDGN CFYRALGYSY 60
LESLLGKSRE VLKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDSSVSSLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGTGAAA CCTCTTTCAA CCTAATATCA GAAAAATGTG ACATTCTATC AATTCTTCGG 60
GATCATCCTG AAAACAGGAT TTACCAGAGG AAAATCCAGG TGAGACAGAG GTTTGCAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012766	Bos taurus	96.12	3.00e-132	463.00
IUUC-Cja-019480	Callithrix jacchus	95.67	1.00e-131	461.00
IUUC-Cfa-021106	Canis familiaris	98.72	6.00e-137	479.00
IUUC-Cpo-022187	Cavia porcellus	94.85	1.00e-131	461.00
IUUC-Csa-023493	Chlorocebus sabaeus	95.28	6.00e-132	462.00
IUUC-Cho-024411	Choloepus hoffmanni	77.07	1.00e-85	308.00
IUUC-Dno-029346	Dasypus novemcinctus	97.00	2.00e-134	471.00
IUUC-Dor-031012	Dipodomys ordii	97.84	2.00e-134	471.00
IUUC-Ete-032266	Echinops telfairi	87.98	4.00e-121	426.00
IUUC-Eca-033356	Equus caballus	96.58	2.00e-134	470.00
IUUC-Eeu-034775	Erinaceus europaeus	95.71	4.00e-133	466.00
IUUC-Fca-035363	Felis catus	95.28	1.00e-132	464.00
IUUC-Ggo-045023	Gorilla gorilla	94.83	6.00e-131	459.00
IUUC-Hsa-046984	Homo sapiens	95.26	1.00e-131	461.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	96.55	2.00e-133	467.00
IUUC-Lch-050514	Latimeria chalumnae	60.44	4.00e-83	300.00
IUUC-Loc-052003	Lepisosteus oculatus	50.00	4.00e-64	237.00
IUUC-Laf-054382	Loxodonta africana	95.73	4.00e-134	469.00
IUUC-Mcc-055516	Macaca mulatta	94.85	1.00e-131	461.00
IUUC-Meu-056038	Macropus eugenii	87.30	1.00e-98	351.00
IUUC-Mmr-060918	Microcebus murinus	97.41	2.00e-134	470.00
IUUC-Mdo-062638	Monodelphis domestica	89.66	3.00e-124	437.00
IUUC-Mmu-063973	Mus musculus	96.57	5.00e-134	470.00
IUUC-Mpu-066013	Mustela putorius furo	99.14	8.00e-137	478.00
IUUC-Mlu-067509	Myotis lucifugus	94.02	7.00e-130	455.00
IUUC-Nle-069673	Nomascus leucogenys	95.26	1.00e-131	461.00
IUUC-Opr-070761	Ochotona princeps	87.27	1.00e-80	291.00
IUUC-Oan-072922	Ornithorhynchus anatinus	82.53	2.00e-113	401.00
IUUC-Ocu-074643	Oryctolagus cuniculus	94.83	1.00e-131	461.00
IUUC-Oni-082026	Oryza nivara	28.32	1.00e-15	77.40
IUUC-Oru-084761	Oryza rufipogon	28.32	1.00e-15	77.40
IUUC-Ola-086603	Oryzias latipes	44.91	1.00e-51	196.00
IUUC-Oga-088936	Otolemur garnettii	95.71	6.00e-133	466.00
IUUC-Oar-089460	Ovis aries	96.57	4.00e-133	466.00
IUUC-Ptr-090805	Pan troglodytes	94.83	4.00e-131	459.00
IUUC-Pan-091969	Papio anubis	95.26	1.00e-131	461.00
IUUC-Pab-098476	Pongo abelii	94.85	2.00e-131	461.00
IUUC-Pca-100252	Procavia capensis	93.00	1.00e-53	202.00
IUUC-Pva-102204	Pteropus vampyrus	95.69	4.00e-133	466.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.40e-02	31.60
IUUC-Rno-105062	Rattus norvegicus	96.55	6.00e-134	469.00
IUUC-Sha-106968	Sarcophilus harrisii	89.57	3.00e-123	434.00
IUUC-Sar-113295	Sorex araneus	97.00	1.00e-132	464.00
IUUC-Ssc-115288	Sus scrofa	96.14	2.00e-133	467.00
IUUC-Tni-120440	Tetraodon nigroviridis	38.96	9.00e-43	166.00
IUUC-Tbe-127717	Tupaia belangeri	94.59	2.00e-78	283.00
IUUC-Ttr-128221	Tursiops truncatus	78.11	4.00e-102	363.00
IUUC-Uma-129443	Ustilago maydis	33.18	2.00e-24	106.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence