iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086996

UUCD1 version

UUC-OrL-01019

Ensembl Protein ID

ENSORLP00000025600.1

UniProt Accession

H2N2C1; H2N2C1_ORYLA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000020667.1	ENSORLT00000025601.1	ENSORLP00000025600.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.00e-101	337.9	564	881

Active Site

Position(s)	Description	Evidence
859	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+vef+gE+g+d gGv++ef++l+++e++npd+g+f+y+e  k  ++ np+s+    e++  ++++G++lg+a++++ +ld+
   Q: 564  PADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDEYTKLFWF-NPSSF----ENEGQYTLIGIVLGLAIYNNCILDV 647
           689******************************************998888876.88888....6799********************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           +++ ++y++l+gkk ++ dl++ +p l +slke++e+ e ++ee ++ +tf+  +++++g+   ++L ++G++ipVtn+N++e+v ++ 
   Q: 648  HFPMVVYRKLMGKKGTFRDLADANPVLNQSLKELLEY-EGSVEE-DMMITFQiSHNDLFGNPLMYDLRENGDKIPVTNDNRREFVAQYS 734
           *************************************.556665.59999994455569****************************** PP
   S: 179  eyrlkegikeqveafreGfneviple.llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLq 266
           +y+l++++++q++afr+Gf+ v +++ l  lF++ee+ellicG++++d+ +l+++t+y+ggy++ds+ i+ Fwe+l++f +e+++ fLq
   Q: 735  DYILNKSVEKQFKAFRRGFHMVTNESpLKYLFRPEEIELLICGSRNLDFLALEETTEYDGGYNRDSRIIKDFWETLHSFGEEQKRLFLQ 823
           ***********************99934558********************************************************** PP
   S: 267  FvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyA 326
           F+Tg++r+P+gG+ +lk   ++i k++ d drlP+s+TCfn+L LPeYssk++l+e+Ll A
   Q: 824  FTTGTDRAPVGGLGKLK---MIIAKNGPDtDRLPTSHTCFNVLLLPEYSSKDKLRERLLKA 881
           *****************...8888866666****************************988 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

EICLSDISYF CISCPRITNR SVSEPGVNKS LIFSSERRKR AAAKHLIERY YHQLTEGCGN 60
ECCSNPWCAS SVGFTRMDNN AAAVKALELY KVNAKLCDPH PSKKGTASTY LESSTHSNSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATCTGCT TGTCTGATAT TTCTTACTTC TGCATTTCCT GTCCTAGAAT AACCAACAGT 60
TATGTCAAAC TTAGAATGCT GTTCTGGTTC CGTTTAGAGG AGCTTAAACA TAAACCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom
IPR017134--UBE3A

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002214	Ailuropoda melanoleuca	85.81	0.00e+00	1414.00
IUUC-Apl-003742	Anas platyrhynchos	84.69	0.00e+00	1429.00
IUUC-Aca-004873	Anolis carolinensis	84.68	0.00e+00	1437.00
IUUC-Ame-011166	Astyanax mexicanus	85.26	0.00e+00	1415.00
IUUC-Bta-013286	Bos taurus	83.91	0.00e+00	1380.00
IUUC-Cja-019707	Callithrix jacchus	84.64	0.00e+00	1410.00
IUUC-Cfa-020154	Canis familiaris	84.18	0.00e+00	1401.00
IUUC-Cpo-021292	Cavia porcellus	85.59	0.00e+00	1407.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	48.87	8.00e-78	283.00
IUUC-Csa-023378	Chlorocebus sabaeus	85.15	0.00e+00	1406.00
IUUC-Cho-025059	Choloepus hoffmanni	82.61	0.00e+00	1338.00
IUUC-Dre-027901	Danio rerio	83.84	0.00e+00	1390.00
IUUC-Dno-029320	Dasypus novemcinctus	85.12	0.00e+00	1417.00
IUUC-Dor-030756	Dipodomys ordii	79.82	6.00e-179	621.00
IUUC-Dme-032035	Drosophila melanogaster	44.09	2.00e-160	559.00
IUUC-Eca-033843	Equus caballus	86.19	0.00e+00	1383.00
IUUC-Eeu-035109	Erinaceus europaeus	84.74	0.00e+00	1368.00
IUUC-Fca-036344	Felis catus	83.85	0.00e+00	1400.00
IUUC-Fal-036747	Ficedula albicollis	85.55	0.00e+00	1426.00
IUUC-Gga-040399	Gallus gallus	85.66	0.00e+00	1428.00
IUUC-Gac-041933	Gasterosteus aculeatus	91.72	0.00e+00	1455.00
IUUC-Ggo-044804	Gorilla gorilla	85.40	0.00e+00	1408.00
IUUC-Hsa-045727	Homo sapiens	85.40	0.00e+00	1408.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	82.47	0.00e+00	1324.00
IUUC-Lch-050197	Latimeria chalumnae	83.37	0.00e+00	1414.00
IUUC-Loc-052743	Lepisosteus oculatus	86.48	0.00e+00	1456.00
IUUC-Laf-053615	Loxodonta africana	84.07	0.00e+00	1421.00
IUUC-Mcc-054934	Macaca mulatta	85.15	0.00e+00	1404.00
IUUC-Meu-056061	Macropus eugenii	82.16	0.00e+00	1299.00
IUUC-Mga-059271	Meleagris gallopavo	85.88	0.00e+00	1421.00
IUUC-Mmr-061288	Microcebus murinus	86.26	0.00e+00	1417.00
IUUC-Mdo-062975	Monodelphis domestica	85.98	0.00e+00	1431.00
IUUC-Mmu-063674	Mus musculus	83.70	0.00e+00	1379.00
IUUC-Mpu-066568	Mustela putorius furo	85.48	0.00e+00	1417.00
IUUC-Mlu-067522	Myotis lucifugus	79.14	0.00e+00	1330.00
IUUC-Nle-069505	Nomascus leucogenys	85.40	0.00e+00	1408.00
IUUC-Opr-070570	Ochotona princeps	78.04	0.00e+00	1269.00
IUUC-Ont-071527	Oreochromis niloticus	92.88	0.00e+00	1550.00
IUUC-Oan-073446	Ornithorhynchus anatinus	83.73	0.00e+00	953.00
IUUC-Ocu-074922	Oryctolagus cuniculus	83.70	0.00e+00	1405.00
IUUC-Oga-088261	Otolemur garnettii	86.19	0.00e+00	1408.00
IUUC-Oar-090024	Ovis aries	83.91	0.00e+00	1380.00
IUUC-Ptr-090455	Pan troglodytes	85.40	0.00e+00	1408.00
IUUC-Pan-092509	Papio anubis	85.66	0.00e+00	1276.00
IUUC-Psi-092974	Pelodiscus sinensis	82.95	0.00e+00	1409.00
IUUC-Pma-094643	Petromyzon marinus	70.74	0.00e+00	1223.00
IUUC-Pfo-096905	Poecilia formosa	91.82	0.00e+00	1520.00
IUUC-Pab-097840	Pongo abelii	84.15	0.00e+00	1361.00
IUUC-Pca-100869	Procavia capensis	84.91	0.00e+00	1399.00
IUUC-Pva-103040	Pteropus vampyrus	87.72	2.00e-174	605.00
IUUC-Rno-105453	Rattus norvegicus	82.33	0.00e+00	1376.00
IUUC-Sha-107651	Sarcophilus harrisii	85.37	0.00e+00	1432.00
IUUC-Sar-113293	Sorex araneus	86.30	0.00e+00	1414.00
IUUC-Ssc-115979	Sus scrofa	86.30	0.00e+00	1416.00
IUUC-Tgu-116901	Taeniopygia guttata	84.69	0.00e+00	1429.00
IUUC-Tru-118368	Takifugu rubripes	92.98	0.00e+00	1527.00
IUUC-Tsy-119516	Tarsius syrichta	82.59	0.00e+00	1304.00
IUUC-Tni-120143	Tetraodon nigroviridis	91.94	0.00e+00	1516.00
IUUC-Tbe-127484	Tupaia belangeri	81.10	0.00e+00	971.00
IUUC-Ttr-129078	Tursiops truncatus	85.58	0.00e+00	1389.00
IUUC-Vpa-130312	Vicugna pacos	77.98	0.00e+00	1192.00
IUUC-Xtr-132881	Xenopus tropicalis	84.43	0.00e+00	1415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence