iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.40e-41	140.6	266	442

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmelees................................................... 37
           aDvilv++ ++++fahki+L++sSs+Fy+lflm+l+e+                                                   
   Q: 266  ADVILVLQeRVRIFAHKIYLSTSSSKFYDLFLMDLSEGelggpsgsggprpedhrshpeqhhhhhhhhhgrdfllraasfdvcesvdea 354
           7**************************************************************************************** PP
   S: 38   .....................................................ksklmveik.d..vqpevfrallkFlYtgkldene 69
                                                                ks+lmv++k d  +qp++fra+lk+lYtg+l ene
   Q: 355  ggsgpaglrastsdgilrgngtgylpgrgrvlsswsrafvsiqeemaedpltfKSRLMVVVKmDnsIQPGPFRAVLKYLYTGELGENE 442
           **************************************************************989*******************9997 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MDSDMDYERP NVETIKCVVV GDNAVGKTRL ICARACNATL TQYQLLATHV PTVWAIDQYR 60
VCQEVLERSR DVVDDVSVSL RLWDTFGDHH KDRRFAYGRS DVVVLCFSIA NPNSLHHVKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATGAAAAA AGGAGGTCGT GAGCGGTCTC GGGGACTGCG GCGCTCGGCG TCTTAAGGCT 60
GCGCGCGTGC GGCGGCCTCA CCCGGCGCCT CGCTCTCTAG CGCGCCGCCC GCAACCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR000210--BTB/POZ_dom
IPR027417--P-loop_NTPase
IPR011333--SKP1/BTB/POZ
IPR001806--Small_GTPase
IPR003578--Small_GTPase_Rho

PROSITE

PS50097--BTB
PS51420--RHO

Pfam

PF00651--BTB
PF00071--Ras

SMART

SM00225--BTB

Gene Ontology

GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0007264--P:small GTPase mediated signal transduction

KEGG

mmu:246710

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002410	Ailuropoda melanoleuca	97.31	0.00e+00	1260.00
IUUC-Apl-003217	Anas platyrhynchos	88.76	0.00e+00	1179.00
IUUC-Aca-005325	Anolis carolinensis	88.42	0.00e+00	1171.00
IUUC-Ame-011099	Astyanax mexicanus	81.70	0.00e+00	1067.00
IUUC-Bta-012867	Bos taurus	93.48	0.00e+00	1189.00
IUUC-Cja-019189	Callithrix jacchus	98.72	0.00e+00	1279.00
IUUC-Cfa-020827	Canis familiaris	98.02	0.00e+00	1125.00
IUUC-Cpo-022064	Cavia porcellus	94.47	0.00e+00	1284.00
IUUC-Csa-023155	Chlorocebus sabaeus	98.44	0.00e+00	1300.00
IUUC-Cin-025684	Ciona intestinalis	50.52	6.00e-70	258.00
IUUC-Csv-026261	Ciona savignyi	54.22	1.00e-49	189.00
IUUC-Dre-028000	Danio rerio	74.93	0.00e+00	994.00
IUUC-Dno-029529	Dasypus novemcinctus	100.00	2.00e-149	522.00
IUUC-Dor-030606	Dipodomys ordii	91.63	0.00e+00	1149.00
IUUC-Ete-032270	Echinops telfairi	85.67	0.00e+00	1095.00
IUUC-Eca-034317	Equus caballus	98.02	0.00e+00	1269.00
IUUC-Eeu-034700	Erinaceus europaeus	94.31	0.00e+00	798.00
IUUC-Fca-036379	Felis catus	98.30	0.00e+00	1263.00
IUUC-Fal-037092	Ficedula albicollis	88.17	0.00e+00	1155.00
IUUC-Gmo-038991	Gadus morhua	80.97	0.00e+00	1066.00
IUUC-Gga-040643	Gallus gallus	89.73	0.00e+00	1199.00
IUUC-Gac-042348	Gasterosteus aculeatus	80.37	0.00e+00	1041.00
IUUC-Hsa-046792	Homo sapiens	98.16	0.00e+00	1283.00
IUUC-Itr-048571	Ictidomys tridecemlineatus	98.86	0.00e+00	1307.00
IUUC-Lch-050574	Latimeria chalumnae	83.05	0.00e+00	1126.00
IUUC-Loc-052678	Lepisosteus oculatus	83.26	0.00e+00	1085.00
IUUC-Laf-054073	Loxodonta africana	97.17	0.00e+00	1296.00
IUUC-Mcc-055721	Macaca mulatta	98.43	0.00e+00	1270.00
IUUC-Mga-059438	Meleagris gallopavo	86.36	0.00e+00	1133.00
IUUC-Mmr-060772	Microcebus murinus	95.32	0.00e+00	1216.00
IUUC-Mdo-062724	Monodelphis domestica	96.46	0.00e+00	1258.00
IUUC-Mpu-066814	Mustela putorius furo	98.57	0.00e+00	1238.00
IUUC-Mlu-067678	Myotis lucifugus	96.71	0.00e+00	1090.00
IUUC-Nle-069747	Nomascus leucogenys	98.44	0.00e+00	1276.00
IUUC-Opr-070707	Ochotona princeps	97.59	0.00e+00	1269.00
IUUC-Ont-071486	Oreochromis niloticus	81.22	0.00e+00	1065.00
IUUC-Ocu-074035	Oryctolagus cuniculus	98.44	0.00e+00	1271.00
IUUC-Ola-086313	Oryzias latipes	81.37	0.00e+00	1023.00
IUUC-Oga-088127	Otolemur garnettii	97.45	0.00e+00	1270.00
IUUC-Ptr-090686	Pan troglodytes	98.16	0.00e+00	1284.00
IUUC-Pan-092489	Papio anubis	98.25	0.00e+00	1105.00
IUUC-Psi-093242	Pelodiscus sinensis	87.34	0.00e+00	1159.00
IUUC-Pfo-096190	Poecilia formosa	80.80	0.00e+00	1042.00
IUUC-Pab-097796	Pongo abelii	98.16	0.00e+00	1281.00
IUUC-Pca-101016	Procavia capensis	92.84	0.00e+00	1118.00
IUUC-Rno-105601	Rattus norvegicus	99.57	0.00e+00	1314.00
IUUC-Sha-107317	Sarcophilus harrisii	95.18	0.00e+00	1107.00
IUUC-Ssc-116044	Sus scrofa	98.58	0.00e+00	1248.00
IUUC-Tgu-116664	Taeniopygia guttata	88.04	0.00e+00	1051.00
IUUC-Tru-118734	Takifugu rubripes	66.71	0.00e+00	870.00
IUUC-Tsy-119544	Tarsius syrichta	79.78	0.00e+00	851.00
IUUC-Tni-120718	Tetraodon nigroviridis	64.85	0.00e+00	810.00
IUUC-Ttr-128382	Tursiops truncatus	90.78	0.00e+00	1179.00
IUUC-Xtr-132039	Xenopus tropicalis	74.40	0.00e+00	962.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence