iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106747

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01200297

Gene Name

BMI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000012897.1	ENSSHAT00000015241.1	ENSSHAP00000015115.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-06	27.9	18	57
ULD/UDP/UFD/RAWUL	1.80e-30	105.4	131	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++            ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 131  ISLSIEFFDQNRLDRKVSkdkekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
           6888888888888776557778888999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 220  PLPLKYR 226
           ******9 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNTGC 60
AGCTCGCTTC AAGATGGCCG CTTGGCTCAC ATTCATTTTC TGCTGAACGA CTTTTAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

KEGG

shr:100928474

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001498	Ailuropoda melanoleuca	97.24	6.00e-165	572.00
IUUC-Apl-004208	Anas platyrhynchos	96.88	2.00e-137	481.00
IUUC-Aca-004661	Anolis carolinensis	84.05	3.00e-139	487.00
IUUC-Ath-007649	Arabidopsis thaliana	42.50	3.00e-12	66.60
IUUC-Ame-010610	Astyanax mexicanus	71.82	1.00e-133	468.00
IUUC-Bta-012606	Bos taurus	97.85	2.00e-166	578.00
IUUC-Cja-019482	Callithrix jacchus	97.77	4.00e-171	593.00
IUUC-Cfa-020482	Canis familiaris	97.24	6.00e-165	572.00
IUUC-Cpo-022061	Cavia porcellus	97.77	2.00e-171	594.00
IUUC-Csa-024102	Chlorocebus sabaeus	98.09	1.00e-172	598.00
IUUC-Cho-025081	Choloepus hoffmanni	80.32	2.00e-110	390.00
IUUC-Cin-025612	Ciona intestinalis	49.07	3.00e-52	198.00
IUUC-Csv-026203	Ciona savignyi	38.21	2.00e-38	152.00
IUUC-Dre-027929	Danio rerio	78.22	1.00e-139	488.00
IUUC-Dno-029797	Dasypus novemcinctus	97.13	7.00e-178	615.00
IUUC-Dor-030256	Dipodomys ordii	94.59	2.00e-159	554.00
IUUC-Dme-031904	Drosophila melanogaster	45.02	9.00e-53	202.00
IUUC-Ete-033148	Echinops telfairi	64.29	2.00e-82	298.00
IUUC-Eca-033318	Equus caballus	97.85	2.00e-166	577.00
IUUC-Eeu-034547	Erinaceus europaeus	85.03	2.00e-141	494.00
IUUC-Fca-035866	Felis catus	97.85	7.00e-166	575.00
IUUC-Fal-036660	Ficedula albicollis	96.93	2.00e-161	560.00
IUUC-Gmo-039341	Gadus morhua	82.69	1.00e-125	442.00
IUUC-Gga-040611	Gallus gallus	96.50	6.00e-161	559.00
IUUC-Gac-041888	Gasterosteus aculeatus	71.30	2.00e-126	444.00
IUUC-Gma-042798	Glycine max	39.51	6.00e-12	65.10
IUUC-Ggo-045027	Gorilla gorilla	98.09	1.00e-171	595.00
IUUC-Hsa-045665	Homo sapiens	98.09	2.00e-172	598.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	97.45	6.00e-169	586.00
IUUC-Lch-049714	Latimeria chalumnae	87.16	3.00e-161	560.00
IUUC-Lpe-051490	Leersia perrieri	42.03	1.00e-11	64.30
IUUC-Loc-052161	Lepisosteus oculatus	81.65	4.00e-142	497.00
IUUC-Laf-054108	Loxodonta africana	95.91	4.00e-169	586.00
IUUC-Mcc-055562	Macaca mulatta	98.09	2.00e-172	598.00
IUUC-Meu-056709	Macropus eugenii	98.77	1.00e-173	601.00
IUUC-Mtr-058158	Medicago truncatula	43.42	3.00e-10	57.40
IUUC-Mga-060104	Meleagris gallopavo	93.98	2.00e-115	407.00
IUUC-Mmr-061191	Microcebus murinus	98.09	1.00e-172	598.00
IUUC-Mdo-062711	Monodelphis domestica	93.17	3.00e-153	533.00
IUUC-Mmu-064255	Mus musculus	93.63	3.00e-158	550.00
IUUC-Mpu-066466	Mustela putorius furo	96.93	6.00e-165	572.00
IUUC-Mlu-067622	Myotis lucifugus	97.45	1.00e-170	591.00
IUUC-Nle-069253	Nomascus leucogenys	98.09	1.00e-172	598.00
IUUC-Opr-070511	Ochotona princeps	96.82	2.00e-170	590.00
IUUC-Ont-072177	Oreochromis niloticus	84.29	3.00e-129	454.00
IUUC-Oan-073336	Ornithorhynchus anatinus	99.08	3.00e-172	597.00
IUUC-Ocu-074113	Oryctolagus cuniculus	98.09	2.00e-161	561.00
IUUC-Ola-087057	Oryzias latipes	84.55	5.00e-124	437.00
IUUC-Oga-088346	Otolemur garnettii	98.09	1.00e-171	595.00
IUUC-Oar-089843	Ovis aries	97.85	2.00e-166	578.00
IUUC-Ptr-090486	Pan troglodytes	98.09	1.00e-171	595.00
IUUC-Pan-092667	Papio anubis	98.48	3.00e-158	551.00
IUUC-Psi-093469	Pelodiscus sinensis	96.01	1.00e-172	598.00
IUUC-Pma-094481	Petromyzon marinus	74.04	1.00e-89	322.00
IUUC-Ppa-095526	Physcomitrella patens	41.38	9.00e-10	58.20
IUUC-Pfo-097156	Poecilia formosa	79.39	6.00e-133	466.00
IUUC-Pab-097670	Pongo abelii	98.09	1.00e-171	595.00
IUUC-Pop-099100	Populus trichocarpa	37.65	2.00e-12	67.00
IUUC-Ppe-102026	Prunus persica	36.46	1.00e-12	67.40
IUUC-Pva-102800	Pteropus vampyrus	98.09	1.00e-171	595.00
IUUC-Rno-105128	Rattus norvegicus	92.99	7.00e-161	559.00
IUUC-Sly-111012	Solanum lycopersicum	45.07	8.00e-13	68.20
IUUC-Stu-112047	Solanum tuberosum	45.07	1.00e-12	67.40
IUUC-Sar-113416	Sorex araneus	97.45	7.00e-171	592.00
IUUC-Sbi-114697	Sorghum bicolor	40.85	2.00e-10	60.10
IUUC-Ssc-115864	Sus scrofa	97.77	1.00e-171	595.00
IUUC-Tgu-116851	Taeniopygia guttata	96.18	4.00e-136	476.00
IUUC-Tru-117698	Takifugu rubripes	85.20	1.00e-124	439.00
IUUC-Tsy-119590	Tarsius syrichta	98.09	1.00e-171	595.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.46	2.00e-128	451.00
IUUC-Tbe-127790	Tupaia belangeri	97.77	3.00e-171	593.00
IUUC-Ttr-129316	Tursiops truncatus	98.09	2.00e-175	607.00
IUUC-Vpa-130669	Vicugna pacos	98.16	1.00e-166	578.00
IUUC-Xtr-131912	Xenopus tropicalis	88.38	2.00e-145	507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence