iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000054792.15	ENSMUST00000068025.12	ENSMUSP00000069674.6
ENSMUSG00000054792.15	ENSMUST00000197336.4	ENSMUSP00000143717.1
ENSMUSG00000054792.15	ENSMUST00000198164.4	ENSMUSP00000143634.1
ENSMUSG00000054792.15	ENSMUST00000200256.1	ENSMUSP00000142820.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.30e-20	73.0	38	103
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-10	39.5	137	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l++g+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 38   CDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGNLAI 103
           9*************************************.************************9865 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++fi++hF
   Q: 137  PKNCLGVRQFAETMMCAVLYDAANSFIHQHF 167
           68***************************** PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 60
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGN LAIDQQNVQS LLMGASFLQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTTCGCGT TCTGGGCAGC CTTCAGCGTG AGCCCTTGCC CCGCCCTGGT TAGTGTGAAG 60
CCTGCTGGCC AGGCCTGCGC AGTTGCGGCG GCCGGGGAAG ATGGTGGAGG ACGGCGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	97.24	0.00e+00	1172.00
IUUC-Apl-003270	Anas platyrhynchos	89.18	0.00e+00	992.00
IUUC-Aca-005395	Anolis carolinensis	90.18	0.00e+00	1080.00
IUUC-Bta-013481	Bos taurus	97.24	0.00e+00	1181.00
IUUC-Cel-018622	Caenorhabditis elegans	44.27	4.00e-141	494.00
IUUC-Cja-019847	Callithrix jacchus	97.93	0.00e+00	1176.00
IUUC-Cfa-020341	Canis familiaris	97.24	0.00e+00	1172.00
IUUC-Cpo-021613	Cavia porcellus	95.76	0.00e+00	1078.00
IUUC-Csa-023611	Chlorocebus sabaeus	97.93	0.00e+00	1177.00
IUUC-Cho-024605	Choloepus hoffmanni	80.94	3.00e-136	478.00
IUUC-Cin-025289	Ciona intestinalis	53.75	0.00e+00	635.00
IUUC-Dre-028248	Danio rerio	82.81	0.00e+00	1009.00
IUUC-Dno-029609	Dasypus novemcinctus	96.20	0.00e+00	1163.00
IUUC-Dor-030541	Dipodomys ordii	96.88	4.00e-150	524.00
IUUC-Dme-032107	Drosophila melanogaster	54.46	0.00e+00	652.00
IUUC-Eca-033507	Equus caballus	97.58	0.00e+00	1095.00
IUUC-Eeu-034750	Erinaceus europaeus	88.06	0.00e+00	965.00
IUUC-Fca-035731	Felis catus	97.75	0.00e+00	1181.00
IUUC-Fal-036959	Ficedula albicollis	89.81	0.00e+00	1046.00
IUUC-Gga-040166	Gallus gallus	93.47	0.00e+00	1119.00
IUUC-Ggo-044853	Gorilla gorilla	97.93	0.00e+00	1177.00
IUUC-Hsa-046437	Homo sapiens	97.58	0.00e+00	1169.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	97.95	0.00e+00	1085.00
IUUC-Lch-050195	Latimeria chalumnae	77.84	0.00e+00	906.00
IUUC-Loc-051787	Lepisosteus oculatus	85.29	0.00e+00	981.00
IUUC-Laf-053489	Loxodonta africana	96.55	0.00e+00	1165.00
IUUC-Mcc-055250	Macaca mulatta	98.79	0.00e+00	1195.00
IUUC-Meu-056871	Macropus eugenii	87.99	0.00e+00	1033.00
IUUC-Mtr-058180	Medicago truncatula	33.62	3.00e-35	144.00
IUUC-Mga-059425	Meleagris gallopavo	93.47	0.00e+00	1113.00
IUUC-Mmr-061394	Microcebus murinus	99.31	0.00e+00	1204.00
IUUC-Mdo-062285	Monodelphis domestica	94.52	0.00e+00	1122.00
IUUC-Mpu-066369	Mustela putorius furo	97.58	0.00e+00	1174.00
IUUC-Mlu-067832	Myotis lucifugus	93.52	0.00e+00	1056.00
IUUC-Nle-069338	Nomascus leucogenys	90.53	0.00e+00	1058.00
IUUC-Opr-071035	Ochotona princeps	84.70	0.00e+00	921.00
IUUC-Ont-071440	Oreochromis niloticus	81.93	0.00e+00	966.00
IUUC-Ola-087275	Oryzias latipes	80.73	0.00e+00	959.00
IUUC-Oga-087921	Otolemur garnettii	98.62	0.00e+00	1188.00
IUUC-Oar-089968	Ovis aries	90.33	0.00e+00	1055.00
IUUC-Ptr-091272	Pan troglodytes	97.93	0.00e+00	1177.00
IUUC-Pan-092629	Papio anubis	97.75	0.00e+00	1173.00
IUUC-Psi-093456	Pelodiscus sinensis	93.12	0.00e+00	991.00
IUUC-Pma-094509	Petromyzon marinus	68.42	0.00e+00	789.00
IUUC-Pfo-096450	Poecilia formosa	78.77	0.00e+00	959.00
IUUC-Pab-097917	Pongo abelii	97.75	0.00e+00	1175.00
IUUC-Pop-099153	Populus trichocarpa	32.76	9.00e-35	142.00
IUUC-Pca-100330	Procavia capensis	97.32	2.00e-175	608.00
IUUC-Pva-103189	Pteropus vampyrus	98.10	0.00e+00	1181.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	33.75	9.00e-07	47.00
IUUC-Sha-107283	Sarcophilus harrisii	94.53	0.00e+00	1088.00
IUUC-Sar-112989	Sorex araneus	96.08	0.00e+00	1075.00
IUUC-Tgu-117146	Taeniopygia guttata	81.23	0.00e+00	911.00
IUUC-Tru-118132	Takifugu rubripes	81.29	0.00e+00	944.00
IUUC-Tsy-119058	Tarsius syrichta	80.94	2.00e-137	482.00
IUUC-Tni-120892	Tetraodon nigroviridis	78.77	0.00e+00	946.00
IUUC-Tbe-127347	Tupaia belangeri	95.34	0.00e+00	1142.00
IUUC-Ttr-128343	Tursiops truncatus	74.81	0.00e+00	780.00
IUUC-Vpa-130796	Vicugna pacos	84.11	0.00e+00	974.00
IUUC-Xtr-132077	Xenopus tropicalis	82.46	0.00e+00	942.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence