iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120263

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 2

Genbank Nucleotide ID

EF195754

Gene Name

socs2; SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000006108.1	ENSTNIT00000009022.1	ENSTNIP00000008851.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	54.26	5.00e-55	211.00	IUUC-Hsa-046557

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MTCQSSETTQ TTERDRGASD ASRAVEADES CITSAMKDLR NTGWYWGSLT ANEAKEILQD 60
TSEGTFLLRD SSQRDYLFTI SAMTSAGPTN LRIEYKHGKF KLDSVVLLKP KLKQFDSVVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCTGTC AGTCATCCGA GACCACCCAA ACGACTGAGC GTGACCGTGG AGCCAGCGAC 60
GCCTCCAGAG CTGTGGAAGC AGACGAGAGC TGCATCACCT CGGCCATGAA GGACCTGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	52.79	8.00e-58	216.00
IUUC-Apl-003484	Anas platyrhynchos	58.12	2.00e-52	197.00
IUUC-Aca-004253	Anolis carolinensis	55.29	9.00e-55	205.00
IUUC-Ame-011267	Astyanax mexicanus	69.48	3.00e-78	284.00
IUUC-Bta-013183	Bos taurus	60.87	5.00e-55	206.00
IUUC-Cja-018862	Callithrix jacchus	62.50	1.00e-55	208.00
IUUC-Cfa-020226	Canis familiaris	61.01	8.00e-54	202.00
IUUC-Cpo-022414	Cavia porcellus	63.19	2.00e-55	208.00
IUUC-Csa-023758	Chlorocebus sabaeus	61.88	2.00e-55	208.00
IUUC-Cho-024471	Choloepus hoffmanni	57.86	1.00e-45	175.00
IUUC-Dre-028288	Danio rerio	72.64	2.00e-85	307.00
IUUC-Dno-029036	Dasypus novemcinctus	53.81	2.00e-59	221.00
IUUC-Dor-030447	Dipodomys ordii	60.76	2.00e-53	200.00
IUUC-Ete-033023	Echinops telfairi	55.98	2.00e-56	211.00
IUUC-Fca-036469	Felis catus	61.88	4.00e-55	206.00
IUUC-Fal-036642	Ficedula albicollis	56.17	3.00e-51	194.00
IUUC-Gmo-039331	Gadus morhua	76.23	1.00e-50	191.00
IUUC-Gga-040809	Gallus gallus	56.63	1.00e-53	201.00
IUUC-Gac-041398	Gasterosteus aculeatus	75.12	3.00e-86	310.00
IUUC-Ggo-045341	Gorilla gorilla	61.88	2.00e-55	208.00
IUUC-Hsa-046557	Homo sapiens	52.79	2.00e-57	214.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	59.88	2.00e-54	204.00
IUUC-Lch-050160	Latimeria chalumnae	56.28	4.00e-57	213.00
IUUC-Loc-051825	Lepisosteus oculatus	72.14	4.00e-83	300.00
IUUC-Laf-053560	Loxodonta africana	61.25	1.00e-54	205.00
IUUC-Mcc-055890	Macaca mulatta	61.25	5.00e-55	206.00
IUUC-Meu-056218	Macropus eugenii	56.10	4.00e-60	223.00
IUUC-Mga-059755	Meleagris gallopavo	57.23	1.00e-51	195.00
IUUC-Mvi-060489	Microbotryum violaceum	31.48	4.60e-01	28.90
IUUC-Mmr-061387	Microcebus murinus	61.88	3.00e-55	207.00
IUUC-Mdo-062383	Monodelphis domestica	56.10	2.00e-61	228.00
IUUC-Mmu-063443	Mus musculus	60.62	4.00e-54	203.00
IUUC-Mpu-066459	Mustela putorius furo	61.88	3.00e-54	204.00
IUUC-Mlu-068040	Myotis lucifugus	52.79	6.00e-57	213.00
IUUC-Nle-069016	Nomascus leucogenys	61.64	9.00e-55	205.00
IUUC-Opr-071087	Ochotona princeps	55.73	7.00e-56	209.00
IUUC-Ont-072340	Oreochromis niloticus	76.62	5.00e-90	323.00
IUUC-Oan-073443	Ornithorhynchus anatinus	57.22	2.00e-59	221.00
IUUC-Ocu-074539	Oryctolagus cuniculus	60.38	8.00e-53	199.00
IUUC-Ola-087004	Oryzias latipes	76.73	7.00e-69	252.00
IUUC-Oga-088438	Otolemur garnettii	61.88	2.00e-55	208.00
IUUC-Oar-089932	Ovis aries	60.87	8.00e-55	206.00
IUUC-Ptr-091037	Pan troglodytes	61.88	2.00e-55	208.00
IUUC-Pan-092767	Papio anubis	61.88	1.00e-55	208.00
IUUC-Psi-093099	Pelodiscus sinensis	59.04	1.00e-54	205.00
IUUC-Pma-094671	Petromyzon marinus	43.90	2.00e-34	139.00
IUUC-Pfo-097073	Poecilia formosa	74.13	2.00e-83	301.00
IUUC-Pab-098319	Pongo abelii	59.41	4.00e-57	213.00
IUUC-Pca-101117	Procavia capensis	61.88	7.00e-55	206.00
IUUC-Pva-102117	Pteropus vampyrus	61.88	2.00e-54	204.00
IUUC-Rno-105913	Rattus norvegicus	60.62	1.00e-54	205.00
IUUC-Sha-106500	Sarcophilus harrisii	55.94	7.00e-59	219.00
IUUC-Sar-113001	Sorex araneus	42.27	1.00e-37	149.00
IUUC-Ssc-115252	Sus scrofa	61.49	5.00e-55	206.00
IUUC-Tgu-117524	Taeniopygia guttata	56.63	5.00e-53	199.00
IUUC-Tsy-119335	Tarsius syrichta	60.13	8.00e-53	198.00
IUUC-Tbe-127915	Tupaia belangeri	61.25	1.00e-54	205.00
IUUC-Ttr-128372	Tursiops truncatus	61.49	6.00e-55	206.00
IUUC-Vpa-130422	Vicugna pacos	61.39	1.00e-53	201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence