iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034320

UUCD1 version

UUC-EqC-00835

Ensembl Protein ID

ENSECAP00000012609.1

UniProt Accession

F7D355; F7D355_HORSE

Protein Name

Uncharacterized protein

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014965.1	ENSECAT00000015665.1	ENSECAP00000012609.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-07	30.3	494	532

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           H+  +++laf   + +ll+s+s D tik+ +l t+++++
   Q: 494  HSKQIRGLAFssRSkGLLLSASLDSTIKLTSLETNTVVQ 532
           9999******99446*************98888877766 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAHEAMEYDL HVQLDHLAAD QPAPAVSSQG GPLLLQPAPA QVVSSQGGPL LLQPAPADVV 60
SSQRGPPLLQ PAPQVSIDLT EEVELLGEGS VENVNPGPSE EHTQESGANR TLGVSSLNSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCATG AAGCAATGGA ATATGATCTT CACGTGCAGT TAGATCATCT TGCTGCAGAT 60
CAGCCTGCTC CTGCTCAAGT GGTCAGCAGC CAAGGAGGGC CACTCCTGCT TCAGCCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50294--WD_REPEATS_REGION
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	23.42	1.00e-16	80.90
IUUC-Aml-001188	Ailuropoda melanoleuca	83.66	0.00e+00	1219.00
IUUC-Atr-003034	Amborella trichopoda	28.34	5.00e-19	88.20
IUUC-Apl-003182	Anas platyrhynchos	61.88	0.00e+00	740.00
IUUC-Aca-004619	Anolis carolinensis	61.30	0.00e+00	751.00
IUUC-Aly-006391	Arabidopsis lyrata	26.14	1.00e-31	130.00
IUUC-Ath-007300	Arabidopsis thaliana	24.21	3.00e-30	126.00
IUUC-Ame-010890	Astyanax mexicanus	58.42	2.00e-179	622.00
IUUC-Bta-013051	Bos taurus	76.66	0.00e+00	1104.00
IUUC-Bdi-014519	Brachypodium distachyon	26.10	7.00e-19	89.00
IUUC-Bol-015271	Brassica oleracea	31.49	7.00e-31	128.00
IUUC-Bra-017931	Brassica rapa	30.19	1.00e-30	127.00
IUUC-Cja-019240	Callithrix jacchus	81.37	0.00e+00	1155.00
IUUC-Cfa-021010	Canis familiaris	83.72	0.00e+00	1222.00
IUUC-Cpo-022308	Cavia porcellus	73.44	0.00e+00	994.00
IUUC-Csa-023501	Chlorocebus sabaeus	80.82	0.00e+00	1224.00
IUUC-Cho-024900	Choloepus hoffmanni	73.26	0.00e+00	1049.00
IUUC-Cin-025403	Ciona intestinalis	37.55	4.00e-94	339.00
IUUC-Csv-025819	Ciona savignyi	37.21	5.00e-44	171.00
IUUC-Cme-027123	Cyanidioschyzon merolae	24.64	2.00e-17	83.60
IUUC-Dre-028354	Danio rerio	57.35	2.00e-166	578.00
IUUC-Dno-029400	Dasypus novemcinctus	77.75	0.00e+00	1098.00
IUUC-Dor-030320	Dipodomys ordii	73.00	0.00e+00	850.00
IUUC-Dme-031949	Drosophila melanogaster	28.27	5.00e-46	179.00
IUUC-Ete-032691	Echinops telfairi	60.07	1.00e-148	520.00
IUUC-Fca-035732	Felis catus	84.13	0.00e+00	1176.00
IUUC-Fal-036648	Ficedula albicollis	70.76	0.00e+00	744.00
IUUC-Gmo-038609	Gadus morhua	58.00	6.00e-141	493.00
IUUC-Gga-040522	Gallus gallus	68.27	1.00e-109	389.00
IUUC-Gac-042318	Gasterosteus aculeatus	55.64	1.00e-133	469.00
IUUC-Gma-043184	Glycine max	26.70	2.00e-25	110.00
IUUC-Ggo-044464	Gorilla gorilla	80.82	0.00e+00	1202.00
IUUC-Hsa-045991	Homo sapiens	80.95	0.00e+00	1201.00
IUUC-Hvu-047705	Hordeum vulgare	25.44	1.00e-29	124.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	81.83	0.00e+00	1192.00
IUUC-Lch-050112	Latimeria chalumnae	65.37	0.00e+00	677.00
IUUC-Lpe-051605	Leersia perrieri	25.87	5.00e-17	82.80
IUUC-Loc-052241	Lepisosteus oculatus	62.12	0.00e+00	645.00
IUUC-Lma-053217	Leptosphaeria maculans	40.82	4.00e-06	44.30
IUUC-Laf-054559	Loxodonta africana	79.65	0.00e+00	998.00
IUUC-Mcc-055093	Macaca mulatta	80.82	0.00e+00	1207.00
IUUC-Meu-056417	Macropus eugenii	65.82	0.00e+00	692.00
IUUC-Mtr-058533	Medicago truncatula	23.81	1.00e-28	121.00
IUUC-Mga-059498	Meleagris gallopavo	60.36	0.00e+00	708.00
IUUC-Mmr-061782	Microcebus murinus	79.95	0.00e+00	1165.00
IUUC-Mdo-062053	Monodelphis domestica	72.47	0.00e+00	763.00
IUUC-Mmu-063352	Mus musculus	67.61	0.00e+00	1013.00
IUUC-Mac-064582	Musa acuminata	26.38	2.00e-20	94.40
IUUC-Mpu-066087	Mustela putorius furo	81.03	0.00e+00	1196.00
IUUC-Mlu-068147	Myotis lucifugus	76.95	0.00e+00	1093.00
IUUC-Nle-069503	Nomascus leucogenys	77.48	0.00e+00	1134.00
IUUC-Opr-070479	Ochotona princeps	69.81	0.00e+00	1009.00
IUUC-Ont-071700	Oreochromis niloticus	56.26	2.00e-167	582.00
IUUC-Oan-073702	Ornithorhynchus anatinus	74.09	0.00e+00	789.00
IUUC-Ocu-074886	Oryctolagus cuniculus	78.18	0.00e+00	1150.00
IUUC-Oba-075729	Oryza barthii	24.91	9.00e-25	108.00
IUUC-Obr-076562	Oryza brachyantha	24.56	2.00e-20	94.00
IUUC-Ogl-077615	Oryza glaberrima	24.91	9.00e-25	108.00
IUUC-Ogu-078921	Oryza glumaepatula	25.10	2.00e-25	110.00
IUUC-Oin-079250	Oryza indica	24.45	1.00e-18	87.80
IUUC-Olo-080758	Oryza longistaminata	24.56	9.00e-26	111.00
IUUC-Ome-081707	Oryza meridionalis	26.35	3.00e-20	93.20
IUUC-Oni-083006	Oryza nivara	24.18	3.00e-25	110.00
IUUC-Opu-083650	Oryza punctata	24.71	4.00e-25	109.00
IUUC-Oru-084924	Oryza rufipogon	24.95	1.00e-25	110.00
IUUC-Osa-085820	Oryza sativa	25.10	4.00e-25	109.00
IUUC-Ola-087229	Oryzias latipes	56.67	7.00e-137	480.00
IUUC-Oga-088243	Otolemur garnettii	76.09	0.00e+00	1077.00
IUUC-Oar-089461	Ovis aries	79.85	0.00e+00	1209.00
IUUC-Ptr-090527	Pan troglodytes	81.34	0.00e+00	1200.00
IUUC-Pan-092431	Papio anubis	80.55	0.00e+00	1139.00
IUUC-Psi-093156	Pelodiscus sinensis	70.87	0.00e+00	777.00
IUUC-Pno-094897	Phaeosphaeria nodorum	22.96	2.00e-08	53.10
IUUC-Ppa-095305	Physcomitrella patens	28.88	3.00e-20	94.00
IUUC-Pfo-097065	Poecilia formosa	56.09	4.00e-163	568.00
IUUC-Pab-098272	Pongo abelii	81.34	0.00e+00	1231.00
IUUC-Pop-099827	Populus trichocarpa	26.96	1.00e-31	131.00
IUUC-Pca-100713	Procavia capensis	66.67	0.00e+00	964.00
IUUC-Ppe-102103	Prunus persica	27.14	8.00e-33	134.00
IUUC-Pva-103133	Pteropus vampyrus	89.35	0.00e+00	788.00
IUUC-Ptt-103972	Puccinia triticina	27.04	6.00e-07	48.90
IUUC-Pte-104191	Pyrenophora teres	48.00	3.00e-07	49.30
IUUC-Sha-107628	Sarcophilus harrisii	58.33	0.00e+00	824.00
IUUC-Sit-109891	Setaria italica	25.05	8.00e-25	108.00
IUUC-Sly-111779	Solanum lycopersicum	25.94	1.00e-30	128.00
IUUC-Stu-112817	Solanum tuberosum	40.77	1.00e-18	86.70
IUUC-Sar-113124	Sorex araneus	66.09	0.00e+00	719.00
IUUC-Sbi-114107	Sorghum bicolor	26.36	1.00e-30	127.00
IUUC-Ssc-115850	Sus scrofa	81.59	0.00e+00	1180.00
IUUC-Tgu-117295	Taeniopygia guttata	70.81	0.00e+00	748.00
IUUC-Tru-117539	Takifugu rubripes	56.67	6.00e-168	583.00
IUUC-Tsy-118805	Tarsius syrichta	69.83	1.00e-112	400.00
IUUC-Tni-120274	Tetraodon nigroviridis	57.11	2.00e-166	578.00
IUUC-Tca-121162	Theobroma cacao	30.25	3.00e-30	126.00
IUUC-Tae-124822	Triticum aestivum	25.33	3.00e-30	126.00
IUUC-Tur-126162	Triticum urartu	24.03	3.00e-19	90.10
IUUC-Tbe-127884	Tupaia belangeri	72.57	1.00e-83	303.00
IUUC-Ttr-128665	Tursiops truncatus	78.50	6.00e-167	580.00
IUUC-Vpa-130385	Vicugna pacos	84.02	0.00e+00	1191.00
IUUC-Vvi-131464	Vitis vinifera	27.45	3.00e-26	113.00
IUUC-Xtr-132015	Xenopus tropicalis	59.84	0.00e+00	727.00
IUUC-Xma-133109	Xiphophorus maculatus	56.71	3.00e-163	568.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence