iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019499

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01133200

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000000750.2	ENSCJAT00000001361.2	ENSCJAP00000001283.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.00e-09	37.0	545	583

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f +  +++pC+H fha Cl kw       + +++CP C
   Q: 545  CAICYHEFTTSARITPCNHYFHALCLRKW------LYIQDTCPMC 583
           ********999******************......********** PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAAVGPPQQQ VRMAHQQVWA ALEVALRVPC LYIIDAIFNS YPDSSQSRFC IVLQIFLRLL 60
GIFVSSIVLI LSQRSLFKFY MYSSAFLLAA TSVLVNYYAA LHIDFYGGYN TSAFGIELLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCAGCAA CGGCAGAGGC CGGCGGGCGA GGTCAAGATG GTGGCTCCGC GGGCGGGGGA 60
GGTGGTGGAG GGAGGAGTCA GACCTTAGCC AGCCGGAAAC ACCGACACCC AGAGACCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	96.67	0.00e+00	1220.00
IUUC-Apl-004214	Anas platyrhynchos	84.40	0.00e+00	946.00
IUUC-Aca-005326	Anolis carolinensis	77.44	0.00e+00	966.00
IUUC-Ame-011687	Astyanax mexicanus	73.24	0.00e+00	850.00
IUUC-Bta-013394	Bos taurus	96.54	0.00e+00	1263.00
IUUC-Bci-013813	Botrytis cinerea	41.38	7.00e-08	51.60
IUUC-Cfa-020357	Canis familiaris	96.23	0.00e+00	1230.00
IUUC-Cpo-021924	Cavia porcellus	94.28	0.00e+00	1161.00
IUUC-Csa-023513	Chlorocebus sabaeus	97.44	0.00e+00	1278.00
IUUC-Cho-024285	Choloepus hoffmanni	89.47	0.00e+00	1093.00
IUUC-Cin-025223	Ciona intestinalis	54.31	4.00e-75	274.00
IUUC-Csv-026018	Ciona savignyi	48.24	1.00e-65	242.00
IUUC-Dre-028660	Danio rerio	71.21	0.00e+00	773.00
IUUC-Dno-029463	Dasypus novemcinctus	94.93	2.00e-162	565.00
IUUC-Dor-030728	Dipodomys ordii	93.78	0.00e+00	1114.00
IUUC-Dse-031284	Dothistroma septosporum	44.90	6.00e-09	54.70
IUUC-Dme-032186	Drosophila melanogaster	44.47	1.00e-97	350.00
IUUC-Ete-032368	Echinops telfairi	87.26	0.00e+00	1143.00
IUUC-Eca-034325	Equus caballus	95.34	0.00e+00	1194.00
IUUC-Fca-035537	Felis catus	94.64	0.00e+00	1176.00
IUUC-Fal-037459	Ficedula albicollis	84.17	0.00e+00	925.00
IUUC-Gmo-039442	Gadus morhua	78.65	3.00e-97	348.00
IUUC-Ggr-039921	Gaeumannomyces graminis	31.91	2.00e-08	54.70
IUUC-Gga-041071	Gallus gallus	80.78	0.00e+00	977.00
IUUC-Gac-042483	Gasterosteus aculeatus	66.52	0.00e+00	884.00
IUUC-Ggo-044672	Gorilla gorilla	97.14	0.00e+00	1276.00
IUUC-Hsa-045836	Homo sapiens	96.39	0.00e+00	1238.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	95.43	0.00e+00	1241.00
IUUC-Lch-050073	Latimeria chalumnae	73.20	0.00e+00	973.00
IUUC-Loc-052908	Lepisosteus oculatus	69.62	0.00e+00	922.00
IUUC-Lma-053202	Leptosphaeria maculans	40.74	9.00e-08	50.40
IUUC-Laf-053519	Loxodonta africana	92.93	0.00e+00	1248.00
IUUC-Mcc-054674	Macaca mulatta	96.48	6.00e-108	382.00
IUUC-Mor-057262	Magnaporthe oryzae	32.93	3.00e-08	54.30
IUUC-Mga-059922	Meleagris gallopavo	83.94	0.00e+00	936.00
IUUC-Mmr-061452	Microcebus murinus	94.74	0.00e+00	1204.00
IUUC-Mdo-062412	Monodelphis domestica	89.14	0.00e+00	1168.00
IUUC-Mmu-063147	Mus musculus	92.81	0.00e+00	1208.00
IUUC-Mpu-065929	Mustela putorius furo	96.54	0.00e+00	1233.00
IUUC-Mlu-067899	Myotis lucifugus	92.78	0.00e+00	1188.00
IUUC-Nle-070083	Nomascus leucogenys	97.14	0.00e+00	1273.00
IUUC-Opr-070461	Ochotona princeps	90.85	0.00e+00	1220.00
IUUC-Ont-072256	Oreochromis niloticus	69.51	0.00e+00	895.00
IUUC-Oan-073150	Ornithorhynchus anatinus	84.03	0.00e+00	936.00
IUUC-Ocu-073748	Oryctolagus cuniculus	92.65	0.00e+00	1185.00
IUUC-Oga-088565	Otolemur garnettii	96.19	0.00e+00	1238.00
IUUC-Oar-089432	Ovis aries	96.85	0.00e+00	1175.00
IUUC-Ptr-091422	Pan troglodytes	96.99	0.00e+00	1274.00
IUUC-Pan-092331	Papio anubis	97.29	0.00e+00	1277.00
IUUC-Psi-092933	Pelodiscus sinensis	82.54	0.00e+00	923.00
IUUC-Pfo-097466	Poecilia formosa	64.46	0.00e+00	894.00
IUUC-Pab-098702	Pongo abelii	96.99	0.00e+00	1274.00
IUUC-Pca-100125	Procavia capensis	90.63	0.00e+00	1197.00
IUUC-Pva-102628	Pteropus vampyrus	95.78	0.00e+00	1218.00
IUUC-Rno-104886	Rattus norvegicus	92.84	0.00e+00	1216.00
IUUC-Sha-106702	Sarcophilus harrisii	86.42	0.00e+00	1142.00
IUUC-Ssc-116164	Sus scrofa	95.34	0.00e+00	1248.00
IUUC-Tgu-116829	Taeniopygia guttata	82.52	0.00e+00	963.00
IUUC-Tru-118557	Takifugu rubripes	65.27	0.00e+00	862.00
IUUC-Tsy-119399	Tarsius syrichta	90.75	0.00e+00	663.00
IUUC-Tni-120006	Tetraodon nigroviridis	61.14	0.00e+00	751.00
IUUC-Tbe-127664	Tupaia belangeri	94.42	0.00e+00	1226.00
IUUC-Ttr-129144	Tursiops truncatus	95.64	0.00e+00	1281.00
IUUC-Vpa-130226	Vicugna pacos	96.54	0.00e+00	1260.00
IUUC-Xtr-132461	Xenopus tropicalis	70.94	0.00e+00	904.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence