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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046508
Ensembl Protein ID ENSP00000312442.5
UniProt Accession O75843; D3DS51; O75504; AP1G2_HUMAN
Genbank Protein ID BAA33390.1; AAC67390.1; EAW66132.1; EAW66134.1; EAW66138.1
Protein Name AP-1 complex subunit gamma-like 2; Gamma2-adaptin
Genbank Nucleotide ID AB015318; AF068706; CH471078; CH471078; CH471078
Gene Name AP1G2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000213983.11 ENST00000308724.9 ENSP00000312442.5
ENSG00000213983.11 ENST00000554477.1 ENSP00000450805.1
ENSG00000213983.11 ENST00000557162.1 ENSP00000450588.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
circBasecircRNADbCircNetmicroRNA
TRANSFACTargetScanRepTarmiRNAMap
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UIM UIM 16867982
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).
 May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).
Protein Sequence
(Fasta)
MVVPSLKLQD LIEEIRGAKT QAQEREVIQK ECAHIRASFR DGDPVHRHRQ LAKLLYVHML 60
GYPAHFGQME CLKLIASSRF TDKRVGYLGA MLLLDERHDA HLLITNSIKN DLSQGIQPVQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046508|UBD,UIM|Homo sapiens
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Nucleotide Sequence
(Fasta)
AAAAAAAATA TATTAATAAA AAAGTTCAAA AAAGGGGGGG GATTGTCATC TCCTTTGGGG 60
TGCGATGGCT TCAAATCCAA ACTGAGGCTC TCCGGGTGGT AAGGATGTGC GAGGAGGCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046508|UBD,UIM|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0967--Endosome
KW-0333--Golgi apparatus
KW-0945--Host-virus interaction
KW-0472--Membrane
KW-0621--Polymorphism
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR017107--AP1_complex_gsu
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR002553--Clathrin/coatomer_adapt-like_N
IPR008152--Clathrin_a/b/g-adaptin_app_Ig
IPR008153--Clathrin_g-adaptin_app
IPR013041--Coatomer/clathrin_app_Ig-like
PROSITE

PS50180--GAE
Pfam

PF01602--Adaptin_N
PF02883--Alpha_adaptinC2
SMART

SM00809--Alpha_adaptinC2
Gene Ontology

GO:0030121--C:AP-1 adaptor complex
GO:0010008--C:endosome membrane
GO:0005794--C:Golgi apparatus
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016020--C:membrane
GO:0030133--C:transport vesicle
GO:0008565--F:protein transporter activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport
GO:0016032--P:viral process
KEGG hsa:8906
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001927 Ailuropoda melanoleuca 87.35 0.00e+00 1260.00
IUUC-Bta-012396 Bos taurus 89.02 0.00e+00 1059.00
IUUC-Cja-019267 Callithrix jacchus 86.61 0.00e+00 1058.00
IUUC-Cfa-020381 Canis familiaris 89.61 0.00e+00 1248.00
IUUC-Cpo-021411 Cavia porcellus 86.01 0.00e+00 1177.00
IUUC-Csa-023574 Chlorocebus sabaeus 96.94 0.00e+00 1336.00
IUUC-Dre-028339 Danio rerio 58.43 0.00e+00 896.00
IUUC-Dno-030066 Dasypus novemcinctus 88.40 0.00e+00 1295.00
IUUC-Dor-031086 Dipodomys ordii 86.31 0.00e+00 926.00
IUUC-Eca-033211 Equus caballus 91.97 0.00e+00 1332.00
IUUC-Eeu-034574 Erinaceus europaeus 81.27 0.00e+00 1146.00
IUUC-Ggo-044758 Gorilla gorilla 99.24 0.00e+00 1372.00
IUUC-Itr-048524 Ictidomys tridecemlineatus 92.24 0.00e+00 1296.00
IUUC-Laf-054160 Loxodonta africana 90.32 0.00e+00 1265.00
IUUC-Mcc-055299 Macaca mulatta 97.07 0.00e+00 1341.00
IUUC-Meu-056526 Macropus eugenii 81.71 0.00e+00 1125.00
IUUC-Mmr-061441 Microcebus murinus 92.10 0.00e+00 1293.00
IUUC-Mdo-062443 Monodelphis domestica 78.50 0.00e+00 1118.00
IUUC-Mmu-063539 Mus musculus 86.73 0.00e+00 1267.00
IUUC-Mpu-065857 Mustela putorius furo 90.32 0.00e+00 1268.00
IUUC-Mlu-067650 Myotis lucifugus 89.81 0.00e+00 1236.00
IUUC-Nle-069751 Nomascus leucogenys 97.96 0.00e+00 1314.00
IUUC-Opr-071071 Ochotona princeps 86.91 0.00e+00 1125.00
IUUC-Ocu-074118 Oryctolagus cuniculus 87.69 0.00e+00 1185.00
IUUC-Oga-087949 Otolemur garnettii 90.70 0.00e+00 1269.00
IUUC-Oar-090094 Ovis aries 90.06 0.00e+00 1309.00
IUUC-Ptr-091184 Pan troglodytes 99.62 0.00e+00 1379.00
IUUC-Pan-092405 Papio anubis 97.20 0.00e+00 1328.00
IUUC-Pab-097941 Pongo abelii 98.73 0.00e+00 1369.00
IUUC-Pca-100934 Procavia capensis 86.24 0.00e+00 1208.00
IUUC-Pva-102188 Pteropus vampyrus 88.45 0.00e+00 809.00
IUUC-Rno-105192 Rattus norvegicus 87.39 0.00e+00 1254.00
IUUC-Tbe-127973 Tupaia belangeri 88.89 2.00e-136 479.00
Created Date 25-Jun-2017

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